Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community-Healthcare Workers (MOSAR)

Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community- the Role of Healthcare Workers

Medical staff will be screened for MRSA and ESBL (including: doctors, nurses, nurse aids, physical therapists, dietitians, Janitors and other medical staff).

PURPOSE:

To define the carriage of, and risk factors for carriage of resistant organisms among healthcare employees of carriers of resistant bacteria.

To define activities of healthcare employees who likely to lead to dissemination of resistant bacteria in rehabilitation centers.

Study Overview

• Status: Unknown
• Conditions: Methicillin-Resistant Staphylococcus Aureus; ESBL

Detailed Description

Detailed activity:

Medical staff will be screened for MRSA and ESBL (including: doctors, nurses, nurse aids, physical therapists, dietitians, Janitors and other medical staff).

Screening will be performed by obtaining nares and perirectal cultures. Nares cultures will be obtained by ward staff or research personnel who are experienced in performing this activity: a moisture swab will be applied gently to the distal part of both nares. Perirectal cultures, will be taken by swab, who will be applied to the perirectal area, either by staff as mentioned above, or will be given to the healthcare workers to perform by himself (with explanation on how to perform it).

• Study Type: Observational
• Enrollment (Anticipated): 150

Contacts and Locations

Study Locations

• Israel
  • Tel-aviv, Israel, 64239
    • TASMC

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Healthcare employees) including: doctors, nurses, nurse aids, physical therapists, dietitians, Janitors and other medical staff) who work in the rehabilitation center

Description

Inclusion Criteria:

• Health care employees

Exclusion Criteria:

• Age 18 years or less

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Healthcare employees) including: doctors, nurses, nurse aids, physical therapists, dietitians, Janitors and other medical staff) who work in the rehabilitation center	1 YEAR

Collaborators and Investigators

• Sponsor: Tel-Aviv Sourasky Medical Center
• Investigators: Principal Investigator: Yehuda carmeli, MD MPH, TASMC

Publications and helpful links

General Publications

• Albrich WC, Harbarth S. Health-care workers: source, vector, or victim of MRSA? Lancet Infect Dis. 2008 May;8(5):289-301. doi: 10.1016/S1473-3099(08)70097-5.
• Carmeli Y, Venkataraman L, DeGirolami PC, Lichtenberg DA, Karchmer AW, Samore MH. Stool colonization of healthcare workers with selected resistant bacteria. Infect Control Hosp Epidemiol. 1998 Jan;19(1):38-40. doi: 10.1086/647705.

Study record dates

Study Major Dates

• Study Start: October 1, 2008
• Primary Completion (Anticipated): October 1, 2009
• Study Completion (Anticipated): January 1, 2014

Study Registration Dates

• First Submitted: October 6, 2008
• First Submitted That Met QC Criteria: October 15, 2008
• First Posted (Estimate): October 16, 2008

Study Record Updates

• Last Update Posted (Estimate): October 16, 2008
• Last Update Submitted That Met QC Criteria: October 15, 2008
• Last Verified: October 1, 2008

More Information

Terms related to this study

• Keywords: Healthcare employees who work in the rehabilitation center
• Additional Relevant MeSH Terms: Infections; Bacterial Infections; Bacterial Infections and Mycoses; Gram-Positive Bacterial Infections; Staphylococcal Infections
• Other Study ID Numbers: TASMC-08-YC-254-CTIL