- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01016080
Role of Oral Glutathione in Skin Whitening
November 17, 2009 updated by: Chulalongkorn University
Glutathione as an Oral Whitening Agent: a Randomized, Double-blind, Placebo-controlled Study
Oral and intravenous glutathione have been used widely to whiten the skin.
The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.
Study Overview
Study Type
Interventional
Enrollment (Actual)
60
Phase
- Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Bangkok, Thailand, 10330
- King Chulalongkorn Memorial Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
16 years to 23 years (Adult)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Healthy medical students
Exclusion Criteria:
- history of skin cancer, especially melanoma
- consumption of any preparations containing glutathione within 1 month of enrollment
- pigmentary disorders or any dermatoses
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Triple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: oral glutathione
glutathione, 500 mg, taken orally twice daily
|
250 mg capsules, twice daily, orally
|
Placebo Comparator: placebo capsules
identical-appearing placebo capsules
|
250 mg capsules, twice daily, orally
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Skin melanin index
Time Frame: 4 weeks
|
4 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 2009
Primary Completion (Actual)
May 1, 2009
Study Completion (Actual)
June 1, 2009
Study Registration Dates
First Submitted
November 17, 2009
First Submitted That Met QC Criteria
November 17, 2009
First Posted (Estimate)
November 18, 2009
Study Record Updates
Last Update Posted (Estimate)
November 18, 2009
Last Update Submitted That Met QC Criteria
November 17, 2009
Last Verified
November 1, 2009
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- COA840/2008
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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