Endoplasmic Reticulum Stress in Chronic Respiratory Diseases

September 28, 2010 updated by: Chonbuk National University

Endoplasmic Reticulum (ER) Stress in Patients With Various Chronic Pulmonary Diseases

Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders

Measurement:

  1. Unfolded protein responses (UPRs) in blood (PBMCs)of patients

    1. CHOP
    2. GRP 78 and so on

  2. Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls

    1. CHOP
    2. GRP 78 and so on

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Korea, Republic of
    • Jeonbuk
      • Jeonju, Jeonbuk, Korea, Republic of, 561-180
        • Recruiting
        • Chonbuk National University Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

  1. Control group

    • healthy control (volunteer)

  2. Disease group

    • chronic pulmonary lung diseases including asthma, COPD, ILD, and lung cancer

Description

Inclusion Criteria:

  • > 18 yrs
  • Definitive diagnosis as chronic pulmonary diseases by physician

Exclusion Criteria:

  • Any other chronic medical illness such as DM, HTN, and other malignancy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Control group
healthy control group
Disease group
asthma, COPD, ILD, lung malignancy

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Chonbuk National University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2010

Study Registration Dates

First Submitted

September 28, 2010

First Submitted That Met QC Criteria

September 28, 2010

First Posted (Estimate)

September 29, 2010

Study Record Updates

Last Update Posted (Estimate)

September 29, 2010

Last Update Submitted That Met QC Criteria

September 28, 2010

Last Verified

September 1, 2010

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • RCPD ER stress

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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