Influence of Direction of Movement While Walking

Influence of Direction of Movement While Walking Upon the Blood Flow Rate Through Brain, Examined by Transcranial Doppler Sonography in Young Healthy Subjects.

The aim of the study is evaluation of cerebral blood flow (based on testing the rate of flow in middle cerebral arteries by transcranial Doppler ultrasound) during different forms of walking training - walk forwards and backwards, with closed and open eyes.

Study Overview

• Status: Completed
• Conditions: Changes in Blood Flow to the Brain; Changes Depending on the Form of Walking

Detailed Description

In the third minute of training walking a significant increase in blood flow velocity was recorded, both in right and left middle cerebral arteries. It was observed in the left artery during all forms of training. In the right artery it occurred only during three forms of difficult training, and was preceded by significant decrease in blood flow in the first minute of the gait with eyes closed. The output values of the rate of blood flow in both right and left middle cerebral arteries became progressively reduced in the successive stages of gait. Pressure and pulse rates did not correlate with the variables of blood flow velocity in middle cerebral arteries.

• Study Type: Observational
• Enrollment (Actual): 1

Contacts and Locations

Study Locations

• Poland
  • Silesia
    • Katowice, Silesia, Poland, 40-055
      • Medical University of Silesia

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 24 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

20 healthy subjects (11 men, 9 women, average age 23.94) participated in a study measuring the speed of blood flow in middle cerebral arteries using transcranial Doppler (transcranial Doppler Sonography) while walking on a treadmill.

Description

Inclusion Criteria:

• healthy subjects without brain disease

Exclusion Criteria:

• brain disease and walking disfunctions

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
examining group; 20 healthy subjects (11 men, 9 women, average age 23.94)
control group; 6 healthy subjects (3 men, 3 women, average age 23.6)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Transcranial Doppler sonography in young healthy subjects.	Significant changes in blood flow to the brain depending on the form of walking and its conditions were observed. Changes in the right middle cerebral artery were more diverse than in the left artery. Difficulty in walking training forms gave long-term vasodilation.	5 months

Collaborators and Investigators

• Sponsor: Medical University of Silesia

Study record dates

Study Major Dates

• Study Start: December 1, 2008
• Primary Completion (Actual): January 1, 2009
• Study Completion (Actual): April 1, 2009

Study Registration Dates

• First Submitted: November 29, 2010
• First Submitted That Met QC Criteria: December 6, 2010
• First Posted (Estimate): December 7, 2010

Study Record Updates

• Last Update Posted (Estimate): December 7, 2010
• Last Update Submitted That Met QC Criteria: December 6, 2010
• Last Verified: November 1, 2010

More Information

Terms related to this study

• Keywords: blood flow in the middle cerebral artery of brain
• Other Study ID Numbers: BW-07-AM