Bacterial Growth in Vascular Surgery Wounds

The Effect of Bacterial Growth in Vascular Surgery Wounds to the Incidence of Postoperative Wound Infections

The amount and species of bacteria have been shown to have an effect in wound infections in several fields of surgery (such as gastrointestinal and orthopaedic surgery and the surgery of facial area). In vascular surgery, wound infections are a common and expensive complication. The aim of the present study is to investigate the prevalence of bacteria in vascular surgery wounds perioperatively, and determine whether is correlates with the incidence of wound infections postoperatively.

Study Overview

• Status: Completed
• Conditions: Aneurysm; Lower Limb Ischaemia
• Intervention / Treatment: Other: bacterial samples

• Study Type: Observational
• Enrollment (Actual): 100

Contacts and Locations

Study Locations

• Finland
  • Joensuu, Finland, FIN-80210
    • North Karelia Central Hospital, Clinic of Surgery

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

100 patients requiring lower limb vascular surgery due to ischaemic changes and/or lower limb aneurysms.

Description

Inclusion Criteria:

• need for lower limb vascular by-pass surgery

Exclusion Criteria:

• allergic to cefuroxime
• patients refusal to participate

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
bacterial cultures; Bacterial samples are collected preoperatively from urine, nose and possible lower limb ischaemic wounds, perioperatively from inguinal area and wound edges, and twice postoperatively. In addition, in case of a wound infection, bacterial samples are taken for diagnosis as usual.	Other: bacterial samples; bacterial samples taken

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
wound infection	incidence of wound infection after lower limb vascular surgery	3 months

Collaborators and Investigators

• Sponsor: North Karelia Central Hospital

Study record dates

Study Major Dates

• Study Start: January 1, 2012
• Primary Completion (Actual): October 1, 2012
• Study Completion (Actual): November 1, 2012

Study Registration Dates

• First Submitted: January 4, 2012
• First Submitted That Met QC Criteria: January 5, 2012
• First Posted (Estimate): January 6, 2012

Study Record Updates

• Last Update Posted (Estimate): December 17, 2012
• Last Update Submitted That Met QC Criteria: December 13, 2012
• Last Verified: December 1, 2012

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Cardiovascular Diseases; Vascular Diseases; Ischemia; Aneurysm
• Other Study ID Numbers: NKCH-Surg-009