Erectile Dysfunction in Severe Obstructive Sleep Apnea: Effects of CPAP Therapy

Erectile Dysfunction in Severe Obstructive Sleep Apnea : Effects of CPAP Therapy

Obstructive sleep apnea has been linked to erectile dysfunction. Furthermore, small studies suggest that treatment of sleep apnea by continuous positive airway pressure (CPAP) may reverse erectile dysfunction in affected patients. The present study aims to investigate in a larger cohort if severe sleep apnea is independently associated with erectile dysfunction and if 6-12 months of CPAP therapy lead to an improvement of erectile dysfunction.

Study Overview

• Status: Completed
• Conditions: Obstructive Sleep Apnea; Erectile Dysfunction

• Study Type: Observational
• Enrollment (Actual): 200

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

• Sampling Method: Non-Probability Sample

Study Population

male patients with untreated severe sleep apnea (apnea-hypopnea-index > 30/h)

Description

Inclusion Criteria:

• apnea-hypopnea-index > 30/h
• no CPAP therapy
• male gender
• 18-80 years of age
• having or attempting to have regular sexual intercourse

Exclusion Criteria:

• apnea-hypopnea-index < 30/h
• already treated by CPAP
• female gender
• age < 18 or > 80 years
• not having or not attempting to have regular sexual intercourse

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change of erectile function in severe sleep apnea after 6-12 months of CPAP therapy	an established self-administered questionnaire is used to assess changes in erectile function occurring after 6-12 months of CPAP therapy in patients with severe sleep apnea	at the time of diagnosis of sleep apnea and after 6-12 months of CPAP therapy

Collaborators and Investigators

• Sponsor: University of Giessen
• Investigators: Principal Investigator: Richard Schulz, MD, University of Giessen Lung Center, Germany

Study record dates

Study Major Dates

• Study Start: May 1, 2012
• Primary Completion (Actual): December 1, 2015
• Study Completion (Actual): December 1, 2015

Study Registration Dates

• First Submitted: May 9, 2012
• First Submitted That Met QC Criteria: May 14, 2012
• First Posted (Estimate): May 16, 2012

Study Record Updates

• Last Update Posted (Estimate): December 3, 2015
• Last Update Submitted That Met QC Criteria: December 2, 2015
• Last Verified: December 1, 2015

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Nervous System Diseases; Respiratory Tract Diseases; Respiration Disorders; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Signs and Symptoms, Respiratory; Sexual Dysfunctions, Psychological; Sexual Dysfunction, Physiological; Sleep Apnea Syndromes; Sleep Apnea, Obstructive; Apnea; Erectile Dysfunction
• Other Study ID Numbers: GERSAN-1; UGLC (Other Identifier: UGLC)