Diet and Muscle Function In Older Adults (S32)

February 19, 2014 updated by: Wayne Campbell, Purdue University
This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adults.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adult

Study Type

Interventional

Enrollment (Actual)

12

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Indiana
      • West Lafayette, Indiana, United States, 47907
        • Purdue University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

65 years and older (OLDER_ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • 65 years and older

Exclusion Criteria:

  • Diabetic
  • Acute symptoms of cardiovascular disease or congestive heart failure
  • uncontrolled hypertension
  • supplemental oxygen consumption at rest or during exercise
  • lactose intolerance
  • inability to ride a stationary cycle

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Allocation: RANDOMIZED
  • Interventional Model: CROSSOVER
  • Masking: SINGLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Whey protein supplementation
50 grams of whey blended into frozen drink
Dietary supplement: Whey protein supplementation
subjects are asked to consume a smoothie with whey protein added
EXPERIMENTAL: Carbohydrate supplementation
50 grams of polycose blended into frozen drink
Dietary supplement: Carbohydrate (polycose) supplementation
Subjects are asked to consume a beverage with polycose added

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Dietary protein effects on muscle energy use
Time Frame: participants will be measured over an average of 26 days
gross mechanical efficiency of muscle, consuming high and low protein supplements
participants will be measured over an average of 26 days

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effect of protein supplements on food intake
Time Frame: participants will be measured over an average of 26 days
effects of high protein or high carbohydrate supplements on overall energy consumption in older adults.
participants will be measured over an average of 26 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Purdue University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2012

Primary Completion (ACTUAL)

May 1, 2013

Study Completion (ACTUAL)

May 1, 2013

Study Registration Dates

First Submitted

February 12, 2014

First Submitted That Met QC Criteria

February 19, 2014

First Posted (ESTIMATE)

February 24, 2014

Study Record Updates

Last Update Posted (ESTIMATE)

February 24, 2014

Last Update Submitted That Met QC Criteria

February 19, 2014

Last Verified

May 1, 2013

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1203012093

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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