The Influence of Muscle Contraction on the Cardiac Autonomic System

The Influence of Muscle Contraction on the Cardiac Autonomic System at Rest and Activity

Population:

16 children with cerebral palsy, GMFCS 1-3.16 children typically developed, matched for age.

All children aged 6-12 yrs who understand simple commands.

Tools:

1. Polar monitor to record heart rate, attached to chest, in use throughout testing
2. Dynamometer- for assessing muscle strength.
3. Weights

Method:

Each child will be tested once. Both tools will be demonstrated and tried out before actual testing.

With Polar watch attached:

1. 5 min sitting at rest,
2. knee muscle strength assessment with the dynamometer,
3. 15 minutes rest
4. Isometric and isotonic knee muscle contraction at 30% of childs' maximal strength as has assessed by the dynamometer. The child will asked to perform each for 3 minutes, with 5 minutes rest in-between All will be perform in both legs.

Study Overview

• Status: Unknown
• Conditions: Cerebral Palsy

• Study Type: Observational
• Enrollment (Anticipated): 32

Contacts and Locations

• Study Contact: Name: Michal Katz; Email: mkatz@alyn.org

Study Locations

• Israel
  • Jerusalem, Israel, 91090
    • Alyn Children's Rehabilitation Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 6 years to 12 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

children with cerebral palsy

Description

Inclusion Criteria:

• GMFCS I-II
• Unilateral CP

Exclusion Criteria:

• Heart problems

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
cerebral palsy; Age 6-12 years Gross Motor Function Classification System I-II
control; Age 6-12 years

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Heart rate	40 minutes
Heart rate variability	40 minutes

Collaborators and Investigators

• Sponsor: Alyn Pediatric & Adolescent Rehabilitation Hospital

Study record dates

Study Major Dates

• Study Start: April 1, 2016
• Primary Completion (Anticipated): December 1, 2016

Study Registration Dates

• First Submitted: December 2, 2015
• First Submitted That Met QC Criteria: December 2, 2015
• First Posted (Estimate): December 3, 2015

Study Record Updates

• Last Update Posted (Estimate): April 8, 2016
• Last Update Submitted That Met QC Criteria: April 7, 2016
• Last Verified: November 1, 2015

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Brain Damage, Chronic; Cerebral Palsy
• Other Study ID Numbers: 283-15

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED