Relationship Between Musculoskeletal, Sensorimotor and Functional Factors and Nonspecific Chronic Neck Pain

Several factors have been associated with neck pain. Controversy exists regarding the degree of association between some of these factors and neck pain. Information regarding the degree of association of each factor to neck pain is needed for effective prevention and appropriate treatment strategies. The aim of this study is to investigate the association among musculoskeletal, sensorimotor factors and functional disability and occurrence of chronic nonspecific neck pain.

Study Overview

• Status: Completed
• Conditions: Neck Pain
• Intervention / Treatment: Other: assessment

• Study Type: Observational
• Enrollment (Actual): 232

Contacts and Locations

Study Locations

• Iran, Islamic Republic of
  • Tehran, Iran, Islamic Republic of, 1985713831
    • University of Social Welfare and Rehabilitation Sciences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 50 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

subjects with and without neck pain

Description

Inclusion Criteria:

• for subjects with neck pain: experiencing pain for at least 3 months in the last year, having pain score of 3 or more on visual analogue scale.
• for healthy subjects: no history of neck pain

Exclusion Criteria:

• history of cervical discopathy
• any surgery on neck
• traumatic neck injury
• any congenital disorders

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
chronic neck pain; experiencing neck pain for at least 3 months in the last year	Other: assessment
without neck pain (asymptomatic); no history of neck pain	Other: assessment

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
flexor and extensor cervical muscles holding time (second)	2 years
cervical, back, lowback, upper limbs, lower limbs muscles and trunk maximal contraction force against resistance (N)	2 years
head inclination angle, lumbar and thoracic angles in sagittal plane and thoracic angle in the coronal plane (degrees)	2 years
pelvic inclination in the sagittal and coronal planes (degrees)	2 years
cervical, back, low back, upper limbs, lower limbs and trunk range of motion in sagittal and coronal planes (degrees)	2 years
cervical re-positioning error (degrees)	2 years
the result of Dixhallpike test (positive or negative for vertigo and nystagmus)	2 years
neck disability questionnaire score	2 years
distance between T2 spinous process and spine of the scapula (cm)	2 years
the difference between chest circumference at xiphoid process, axillary and umbliqus levels in the inhalation and exhalation phases of respiration (cm)	2 years
the result of the Romberg test (seconds)	2 years
the result of the upper cervical flexion with rotation test (positive/negative)	2 years
the result of the Gaze test (positive/negative)	2 years
pain reproduction test by the algometer at 2.5 kg pressure level (positive/negative)	2 years
visual analogue scale score	2 years

Secondary Outcome Measures

Outcome Measure	Time Frame
Pearson correlation coefficient of the cervical muscles holding time with visual analogue scale score	2 years
Pearson correlation coefficient of the cervical muscles holding time with neck disability index questionnaire score	2 years
Pearson correlation coefficient of cervical, back, lowback, upper limbs, lower limbs muscles and trunk maximal contraction force against resistance with neck disability index questionnaire score	2 years
Pearson correlation coefficient of cervical, back, lowback, upper limbs, lower limbs muscles and trunk maximal contraction force against resistance with visual analogue scale score	2 years
Pearson correlation coefficient of head inclination angle, lumbar and thoracic angles in sagittal plane and thoracic angle in the coronal plane with visual analogue scale score	2 years
Pearson correlation coefficient of head inclination angle, lumbar and thoracic angles in sagittal plane and thoracic angle in the coronal plane with neck disability index score	2 years
Pearson correlation coefficient of pelvic inclination in the sagittal and coronal planes with neck disability index score	2 years
Pearson correlation coefficient of pelvic inclination in the sagittal and coronal planes with visual analogue scale score	2 years
Pearson correlation coefficient of cervical, back, low back, upper limbs, lower limbs and trunk range of motion in sagittal and coronal planes with neck disability index score	2 years
Pearson correlation coefficient of cervical, back, low back, upper limbs, lower limbs and trunk range of motion in sagittal and coronal planes with visual analogue scale score	2 years
Pearson correlation coefficient of the difference between chest circumference at xiphoid process, axillary and umbliqus levels in the inhalation and exhalation phases of respiration with visual analogue scale score	2 years
Pearson correlation coefficient of the difference between chest circumference at xiphoid process, axillary and umbliqus levels in the inhalation and exhalation phases of respiration with neck disability index score	2 years
Pearson correlation coefficient of distance between T2 spinous process and spine of the scapula with neck disability index score	2 years
Pearson correlation coefficient of distance between T2 spinous process and spine of the scapula with visual analogue scale score	2 years
Pearson correlation coefficient of cervical re-positioning error with visual analogue scale score	2 years
Pearson correlation coefficient of cervical re-positioning error with neck disability index score	2 years
Pearson correlation coefficient of Romberg test with neck disability index score	2 years
Pearson correlation coefficient of Romberg test with visual analogue scale score	2 years
Spearman correlation coefficient of pain reproduction test by the algometer at 2.5 kg pressure level with visual analogue scale score	2 years
Spearman correlation coefficient of pain reproduction test by the algometer at 2.5 kg pressure level with neck disability index score	2 years
Spearman correlation coefficient of the result of the upper cervical flexion with rotation test with neck disability index score	2 years
Spearman correlation coefficient of the result of the upper cervical flexion with rotation test with visual analogue scale score	2 years
Spearman correlation coefficient of the result of Dixhallpike test with visual analogue scale score	2 years
Spearman correlation coefficient of the result of Dixhallpike test with neck disability index score	2 years
Spearman correlation coefficient of the result of Gaze test with neck disability index score	2 years
Spearman correlation coefficient of the result of Gaze test with visual analogue scale score	2 years

Collaborators and Investigators

• Sponsor: University of Social Welfare and Rehabilitation Science

Publications and helpful links

General Publications

• Kahlaee AH, Ghamkhar L, Nourbakhsh MR, Arab AM. Strength and Range of Motion in the Contralateral Side to Pain and Pain-Free Regions in Unilateral Chronic Nonspecific Neck Pain Patients. Am J Phys Med Rehabil. 2020 Feb;99(2):133-141. doi: 10.1097/PHM.0000000000001298.

Study record dates

Study Major Dates

• Study Start: October 1, 2015
• Primary Completion (Actual): April 1, 2017
• Study Completion (Actual): April 1, 2017

Study Registration Dates

• First Submitted: April 22, 2016
• First Submitted That Met QC Criteria: May 27, 2016
• First Posted (Estimate): June 3, 2016

Study Record Updates

• Last Update Posted (Actual): May 8, 2017
• Last Update Submitted That Met QC Criteria: May 5, 2017
• Last Verified: May 1, 2017

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Neck Pain
• Other Study ID Numbers: IR.USWR.REC.1394.224