Low Fructose Diet in Diabetes Type 2

Effects of Low Fructose Diet on Glycemic Control in Patients With Type 2 Diabetes

Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..

Study Overview

• Status: Unknown
• Conditions: Fructose Metabolism Disorder
• Intervention / Treatment: Other: low frutose diet

• Study Type: Interventional
• Enrollment (Actual): 48
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years to 70 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

1. Age of 70-40 years
2. body mass index(BMI) between 18.5 and 27
3. Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)

Exclusion Criteria:

1. Pregnancy and lactation
2. Thyroid gland disorders
3. Kidney disease and inflammation
4. Follow the weight loss regimen 6 months before starting the study
5. Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3
6. Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: intervention group; Eight weeks of low fructose diet with a maximum of 12 g of fructose	Other: low frutose diet
No Intervention: control group; Eight weeks of regular diabetic diet with a 15%pro 30%fat 55%CHO

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
fasting blood suger(FBS)	8 weeks
Homeostatic model assessment and insulin resistance(HOMA-IR)	8weeks
insulin	8 weeks

Secondary Outcome Measures

Outcome Measure	Time Frame
Blood pressure	8 weeks
Triglyceride	8 weeks
LDL-C	8 weeks
HDL-C	8 weeks
Total cholestrole	8 weeks

Collaborators and Investigators

• Sponsor: National Nutrition and Food Technology Institute

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2017
• Primary Completion (Actual): October 1, 2017
• Study Completion (Anticipated): November 30, 2017

Study Registration Dates

• First Submitted: November 13, 2017
• First Submitted That Met QC Criteria: November 20, 2017
• First Posted (Actual): November 24, 2017

Study Record Updates

• Last Update Posted (Actual): November 24, 2017
• Last Update Submitted That Met QC Criteria: November 20, 2017
• Last Verified: August 1, 2017

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Metabolic Diseases
• Other Study ID Numbers: 93567

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No