Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

February 16, 2024 updated by: Leung Hin Cheung, Kowloon Hospital, Hong Kong

This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited.

Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: < 28 kg, Female < 18 kg) and low appendicular skeletal mass (Male: < 7.0 kg/m2, Female: < 5.7 kg/m2)

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Actual)

94

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Hong Kong
      • Kowloon, Hong Kong
        • Kowloon Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022.

Description

Inclusion Criteria:

  • Patients aged 60 years old or above
  • Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and;
  • Able to read and write Chinese

Exclusion Criteria:

  • Unable to maintain standing posture for bioimpedance analysis
  • Modified Functional Ambulation Classification (MFAC) ≤ IV
  • Incompetent in giving consent
  • Unable to follow instructions
  • Implanted with metal in any of four limbs
  • Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Prevalence of Sarcopenia
Time Frame: June - December 2022
The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass.
June - December 2022
Grip strength
Time Frame: June - December 2022
Grip strength would be measured with Jamar digital dynamometer.
June - December 2022
Appendicular Skeletal Muscle Mass Index
Time Frame: June - December 2022
Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer.
June - December 2022

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Association between BMI and Sarcopenia.
Time Frame: June - December 2022
BMI would be measured on clinic attendance.
June - December 2022
Association between Frailty and Sarcopenia.
Time Frame: June - December 2022
Clinical Frailty Scale would be documented in clinical consultation.
June - December 2022
Association between Charlson Comorbidities Index and Sarcopenia
Time Frame: June - December 2022
Components of Charlson Comorbidities Index would be extracted from medical record.
June - December 2022
Association between Bone Mineral Densities and Sarcopenia
Time Frame: June - December 2022
Bone mineral densities of spine and neck of femur would be extracted from the report of dual-energy X-ray absorptiometry.
June - December 2022

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Kowloon Hospital, Hong Kong

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 20, 2022

Primary Completion (Actual)

December 12, 2022

Study Completion (Actual)

February 28, 2023

Study Registration Dates

First Submitted

December 21, 2022

First Submitted That Met QC Criteria

January 13, 2023

First Posted (Actual)

January 18, 2023

Study Record Updates

Last Update Posted (Actual)

February 20, 2024

Last Update Submitted That Met QC Criteria

February 16, 2024

Last Verified

February 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KHRehab_LeungHC_1

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Sarcopenia

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Luxembourg

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe