Search clinical trials for: ACT-1004-1239

Total 6459 results

Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239

Healthy

Portugal
Niiki Pharma Inc.

Completed

Dose Escalation Study of NKP-1339 to Treat Advanced Solid Tumors

Solid Tumors

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Assistance Publique - Hôpitaux de Paris
Association Française contre les Myopathies (AFM), Paris; ARS (Association... and other collaborators

Completed

Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls (DOSERAL)

Amyotrophic Lateral Sclerosis

France
Idorsia Pharmaceuticals Ltd.

Completed

A Placebo-controlled Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
Seoul National University Hospital
National Evidence-Based Healthcare Collaborating Agency; National Clinical... and other collaborators

Completed

Efficacy of Self-education Program for Advanced Care Planning(RCT) for General Population

Healthy

Korea, Republic of
Institute for Neurodegenerative Disorders
United States Department of Defense; University of Oklahoma

Completed

Development of Cognitive Assessment Tools in Parkinson Disease (ANAM)

Parkinson Disease

United States
Midnight Pharma, LLC

Completed

Almorexant (ACT-078573) in Elderly Subjects With Chronic Primary Insomnia

Chronic Primary Insomnia

United States
Aqualung Therapeutics Corp.

Not yet recruiting

Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS

Acute Respiratory Distress Syndrome (ARDS)
Accriva Diagnostics

Unknown

Clinical Performance of the Investigational GEM Hemochron® 100 in Populations Ages 18 Years and Older

Blood Coagulation Test

United States
Click Therapeutics, Inc.

Active, not recruiting

An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

Psoriasis | Atopic Dermatitis

United States
ACADIA Pharmaceuticals Inc.

Completed

ACP-104 in Acutely Psychotic Subjects With Schizophrenia

Schizophrenia

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects

Healthy

Portugal
Click Therapeutics, Inc.

Recruiting

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Multiple Sclerosis | Breast Cancer | Lung Cancer

United States
Aqualung Therapeutics Corp.

Completed

First-In-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALT-100

ARDS, Human

Australia
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Recruiting

A Study of STSA-1002 Combined With STSA-1005 in Healthy Subjects

Healthy Subject

China
EuBiologics Co.,Ltd

Completed

Efficacy and Safety of Botulinum Toxin at Moderate to Severe Glabellar Lines

Glabellar Frown Lines

Korea, Republic of
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study of SHR-1209 in the Treatment of Hypercholesterolemia and Hyperlipidemia Ⅲ Stage

Primary Hypercholesterolemia | Mixed Hyperlipemia

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

SHR - 1209 Treatment Efficacy and Safety of the Patients With Hypercholesterolemia Ⅲ Period Clinical Research

Primary Hypercholesterolemia

China
Chang Gung Memorial Hospital

Completed

Comparison of Choosing Free ALT or Free PMT for Reconstruction With Head and Neck Cancer

Head and Neck Cancer | Reconstructive Surgery

Taiwan
Centre Hospitalier Universitaire Vaudois
Lee Ann LAURENT APPLEGATE; Virginie PHILIPPE

Not yet recruiting

Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee

Chondral Defect | Articular Cartilage Defect | Osteochondritis

Switzerland
Shanghai Haiyan Pharmaceutical Technology Co.,...

Recruiting

Safety and Efficacy Study of YZJ-1139 in Insomnia Disorder

Insomnia Disorder

China
University Hospital, Lille

Not yet recruiting

Effect of Attentional Therapy on Post-traumatic Stress Disorder (BATRAUMA)

Post Traumatic Stress Disorder
Karolinska Institutet
Region Stockholm; Forte; Stiftelsen Frimurarna Barnhuset

Active, not recruiting

Internet-delivered ACT (I-Navigator ACT) for Parents of Children With Disabilities

Depression | Stress, Psychological | Intellectual Disability | Anxiety | Neurodevelopmental Disorders | Traumatic Brain Injury | Autism Spectrum Disorder | Parents | Attention Deficit Hyperactivity Disorder | Physical Disability

Sweden
University of Coimbra
Fundação para a Ciência e a Tecnologia

Unknown

iACT With Pain: an ICT-delivered Intervention for Self-management of Chronic Pain (iACT)

Chronic Pain
University College Dublin

Completed

Acceptance and Commitment Therapy (ACT) in Inflammatory Bowel Disease

Inflammatory Bowel Disease

Ireland
Azusa Pacific University

Withdrawn

Culturally Tailored ACT for Black Trauma

Anxiety Disorders | Stress Disorders, Traumatic | Anxiety

United States
University of Colorado, Boulder
Forest Laboratories

Completed

Nebivolol and the Endothelin (ET)-1 System (NETS)

Hypertension | Prehypertension

United States
Georgia State University

Recruiting

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences (CAD)

Child Abuse

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease

Stable Coronary Artery Disease

Denmark, Netherlands, Singapore, Canada, United Kingdom, United States, Germany, Sweden
George Washington University
University of Oklahoma; Addis Ababa University; Pathfinder International; Overseas... and other collaborators

Active, not recruiting

GAGE Act With Her-Ethiopia Evaluation

Adolescent Behavior | Gender

Ethiopia
Salvat

Completed

A Clinical Trial to Assess the Effect of HC-SVT-1001 and HC-SVT-1002 in the Surgical Treatment of Atrophic Pseudarthrosis of Long Bones (Bonecure) (Bonecure)

Pseudoarthrosis

Spain
Dong-A ST Co., Ltd.

Completed

Clinical Study to Evaluate Efficacy and Safety of DA-1229 in Patients With CAVD (DIP-CAVD)

Calcific Aortic Valve Disease

Korea, Republic of
Centocor Ortho Biotech Services, L.L.C.

Completed

A Study of Human Rhinovirus Type 16 (HRV-16) Following Administration in the Nose of Healthy Adult Volunteers

Healthy

United States
VA Office of Research and Development
University of Alabama, Tuscaloosa

Recruiting

Telehealth Acceptance and Commitment Therapy for Older Veterans Experiencing Pandemic-Related Stress (Pan-ACT)

Psychological Stress

United States
Assistance Publique Hopitaux De Marseille

Recruiting

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS (ACT)

Bladder Exstrophy

France
Uppsala University

Terminated

Psychological Treatment in Psychiatric Inpatient Care

Psychosis | Psychiatric Disorder | Psychiatric Hospitalization | Compulsory Psychiatric Care Act | Acceptance & Commitment Therapy

Sweden
Five Prime Therapeutics, Inc.
Parexel

Completed

Safety Study of FP-1039 To Treat Cancer

Advanced Cancer

United States
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With PD or AD and in Healthy Subjects (CLINDE)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease | Healthy Controls

United States
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [123I] AV94 and SPECT in Subjects With Alzheimer Disease in Comparison to Healthy Subjects (AV94)

Alzheimer Disease

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
VA Office of Research and Development

Completed

Telehealth Therapy for Chronic Pain: Comparison of In-person vs. Video-administered ACT for Pain (TTCP)

Chronic Pain

United States
Region Skane

Withdrawn

Acceptance and Commitment Based Group Therapy for Cancer Patients

Cancer | Psychological Distress

Sweden

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