Levels of Inflammation in People With Cardiovascular Disease (POSEIDON) (POSEIDON)

Prevalence of Systemic Inflammation in Patients With Atherosclerotic Cardiovascular Disease and Heart Failure

This study will collect medical and background information from participants with diseases that affect the heart and blood vessels (cardiovascular disease). Participants will continue their normal care and will not get any treatment other than those the study doctor has prescribed.

Study Overview

• Status: Completed
• Conditions: Heart Failure; Chronic Kidney Disease; Cardiovascular Risk
• Intervention / Treatment: Other: No treatment given

• Study Type: Observational
• Enrollment (Actual): 18198

Contacts and Locations

Study Locations

• Argentina
  • Buenos Aires, Argentina, B1704ETD
    • DIM Clinica Privada
  • Buenos Aires, Argentina, B1878GEG
    • Instituto de Investigaciones Clinicas Quilmes SRL
  • Córdoba, Argentina, X5003DCE
    • Instituto Medico DAMIC
  • Mendoza, Argentina, M5500
    • Hospital Luis Lagomaggiore
  • Buenos Aires
    • Bahia Blanca, Buenos Aires, Argentina, B8001HXD
      • Hospital Italiano Regional Sur
    • Coronel Suarez, Buenos Aires, Argentina, 7540
      • Clinica Coronel Suarez
    • La Plata, Buenos Aires, Argentina, B 1900AXI
      • Hospital Italiano de La Plata
    • Lanus Este, Buenos Aires, Argentina, B1824KAJ
      • Centro Médico CIMEL
  • Buenos Aires, Argentina
    • Caba, Buenos Aires, Argentina, Argentina, C1093AAS
      • Fundacion Favaloro
  • Santa Fe
    • Rosario, Santa Fe, Argentina, 2000
      • INECO Neurociencias Orono
• Australia
  • New South Wales
    • Gosford, New South Wales, Australia, 2250
      • Renal Research Gosford
  • Queensland
    • Auchenflower, Queensland, Australia, 4066
      • Advara HeartCare
  • South Australia
    • Leabrook, South Australia, Australia, 5068
      • Advara HeartCare
  • Victoria
    • Geelong, Victoria, Australia, 3220
      • Barwon Health (The Geelong Hospital)
• Brazil
  • Belo Horizonte/MG, Brazil, 30220-140
    • Nucleo de Pesquisa Clinica do Hospital Vera Cruz
  • Brasília, Brazil, 70390903
    • Hospital do Coracao do Brasil
  • Campinas, Brazil, 13060-080
    • IPECC - Instituto de Pesquisa Clinica de Campinas
  • Goiânia, Brazil, 74605-020
    • HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
  • Marília/SP, Brazil, 17515-000
    • ICM - Instituto do Coracao de Marilia
  • Rio de Janeiro, Brazil, 22281-100
    • Instituto D'Or de Pesquisa e Ensino
  • Salvador, Brazil, 40323-010
    • Hospital Ana Nery
  • Sao Jose Rio Preto, Brazil, 15090-000
    • Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto
  • São Bernardo, Brazil, 09715-090
    • CEMEC - Centro Multidisciplinar de Estudos Clínicos
  • São Paulo, Brazil, 99999
    • Universidade Federal de São Paulo - UNIFESP
  • Paraná
    • Campina Grande do Sul, Paraná, Brazil, 83430-000
      • Sociedade Hospitalar Angelina Caron, Brazil
  • Rio Grande Do Sul
    • Porto Alegre, Rio Grande Do Sul, Brazil, 90050-170
      • Irmandade da Santa Casa de Misericordia de Porto Alegre
  • Sao Paulo
    • Campinas, Sao Paulo, Brazil, 13092-133
      • i9 Pesquisas Clínicas
    • São Paulo, Sao Paulo, Brazil, 01323-903
      • Hospital Alemao Oswaldo Cruz
• Canada
  • British Columbia
    • New West Minster, British Columbia, Canada, V3L 3W4
      • Fraser Clinical Trials Inc.
    • North Vancouver, British Columbia, Canada, V7M 2H4
      • North Shore Heart Centre
  • Ontario
    • Cambridge, Ontario, Canada, N1R 6V6
      • Cambridge Cardiac Care Centre
    • Peterborough, Ontario, Canada, K9J 0B2
      • Kawartha Cardiology Clinical Trials
    • Scarborough, Ontario, Canada, M1B 5N1
      • Corcare Cardiovascular Research
    • Scarborough, Ontario, Canada, M1B 5N1
      • Corcare Cardiovascular Research Inc
    • Winchester, Ontario, Canada, K0C 2K0
      • Winchester Dist Memorial Hosp
  • Quebec
    • Brossard, Quebec, Canada, J4Z2K9
      • [Legal] Viacar Recherches Cliniques, Inc.
    • St. Jean sur Richelieu, Quebec, Canada, J3A 1J2
      • CardioVasc HR Inc
    • Trois-Rivières, Quebec, Canada, G8Z 3R9
      • CIUSSS de la Mauricie-et-du-Centre-du-Quebec
• China
  • Harbin, China, 150001
    • The First Affiliated Hospital of Harbin Medical University
  • Jinan, China, 250033
    • The Second Hospital of Shandong University
  • Xi'an, China, 710061
    • The First Affiliated Hospital of Xi'an JiaoTong University-Cardiovascular
  • Beijing
    • Beijing, Beijing, China, 100029
      • Beijing Anzhen Hospital, Capital Medical University
  • Gansu
    • Lanzhou, Gansu, China, 730030
      • NIS-Lanzhou University Second Hospital
  • Guangdong
    • Guangzhou, Guangdong, China, 510120
      • Sun Yat-sen Memorial Hospital, Sun Yat-sen Universtiy
  • Hainan
    • Haikou, Hainan, China, 570311
      • Hainan General Hospital
  • Hunan
    • Changsha, Hunan, China, 410013
      • The Third Xiangya Hospital of Central South University
  • Jiangsu
    • Changzhou, Jiangsu, China, 213000
      • Changzhou No.2 People's Hospital
    • Nanjing, Jiangsu, China, 210011
      • The Second Affiliated Hospital of Nanjing Medical University
    • Suzhou, Jiangsu, China, 215006
      • The First Affiliated Hospital of Soochow University
    • Xuzhou, Jiangsu, China, 221002
      • The Affiliated Hospital of Xuzhou Medical University
    • Yangzhou, Jiangsu, China, 225001
      • Northern Jiangsu People's Hospital
  • Jilin
    • Changchun, Jilin, China, 130041
      • The Second Hospital of Jilin University
    • Changchun, Jilin, China, 130033
      • China-Japan Union Hospital of Jilin University-Cardiology
  • Liaoning
    • Shenyang, Liaoning, China, 110067
      • The People's Hospital of Liaoning Province
• Czechia
  • Praha 1, Czechia, 110 00
    • Nemocnice Na Frantisku
• Denmark
  • Frederiksberg, Denmark, 2000
    • Bispebjerg Og Frederiksberg Hospital
  • Herlev, Denmark, 2730
    • Herlev og Gentofte Hospital
  • Herning, Denmark, 7400
    • Regionshospitalet Gødstrup, Hjertesygdomme
  • Hillerød, Denmark, 3400
    • Hillerød Endokrinologisk amb. H0652
  • Hvidovre, Denmark, 2650
    • Hvidovre Hospital Hjertemedicinsk
  • København S, Denmark, 2300
    • Amager Hospital - Medicinsk Amb
  • København ø, Denmark, 2100
    • Rigshospitalet
  • Roskilde, Denmark, 4000
    • Sjællands Universitetshospital_Roskilde
  • Region Sjælland
    • Holbæk, Region Sjælland, Denmark, 4300
      • Holbæk Sygehus
• France
  • Amiens Cedex 1, France, 80054
    • Centre Hospitalier Universitaire Amiens Picardie-Site Sud
  • Bordeaux, France, 33000
    • Centre Hospitalier Universitaire de Bordeaux - Hopital Saint Andre
  • Bron, France, 69500
    • Hospices Civils de Lyon-Hopital Cardiologique Louis Pradel-1
  • Chambray Les Tours, France, 37170
    • Centre Hospitalier Regional Universitaire de Tours-Hopital Trousseau
  • Compiegne, France, 60200
    • Centre Hospitalier Intercommunal Compiegne - Noyon
  • Dijon, France, 21000
    • Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage
  • Grenoble cedex 9, France, 38043
    • Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon-1
  • Le Chesnay-Rocquencourt, France, 78150
    • Centre Hospitalier de Versailles-Hôpital André Mignot
  • Le Coudray, France, 28630
    • Les Hopitaux de Chartres-Hopital Louis Pasteur
  • Limoges, France, 87000
    • Centre Hospitalier Et Universitaire de Limoges-Hopital Dupuytren
  • Lyon, France, 69007
    • Centre Hospitalier Saint Joseph Saint Luc
  • Montauban, France, 82000
    • Clinique Pont de Chaume
  • Montpellier Cedex 5, France, 34295
    • Centre Hospitalier Universitaire de Montpellier-Hopital Saint-Eloi
  • Nice, France, 06000
    • Centre Hospitalier Universitaire de Nice-Hopital Pasteur
  • Nimes Cedex 9, France, 30029
    • Centre Hospitalier Universitaire de Nimes-Hopital Caremeau
  • ORLEANS Cedex 2, France, 45067
    • Centre Hospitalier Universitaire d'Orléans
  • Paris, France, 75014
    • Ap-Hp-Hopital Cochin
  • Paris, France, 75004
    • Ap-Hp-Hopital Hotel Dieu Paris
  • Pau, France, 64000
    • Centre Hospitalier de Pau - Hôpital François Mitterrand
  • Poitiers, France, 86000
    • Centre Hospitalier Universitaire de Poitiers
  • Rennes, France, 35000
    • Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou
  • Rouen, France, 76000
    • Clinique Saint Hilaire
  • Saint Herblain, France, 44800
    • Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1
  • Saint Ouen Sur Seine, France, 93400
    • Aura Paris
  • Toulon, France, 83100
    • Centre Hospitalier Intercommunal Toulon La Seine-Sur-Mer - Hopital Sainte Musse
  • Toulouse Cedex 9, France, 31059
    • Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1
  • Vandoeuvre Les Nancy, France, 54500
    • Chru de Nancy - Hopital Brabois
• Germany
  • Berlin, Germany, 12203
    • Charité - Campus Benjamin Franklin - Klinik für Kardiologie, Angiologie und Intensivmedizin
  • Berlin, Germany, 13353
    • Charité - Campus Virchow-Klinikum - Kardiologie, Angiologie und Intensivmedizin (CRU)
  • Bonn, Germany, 53127
    • Universitätsklinikum Bonn (AöR) - Medizinische Klinik und Poliklinik II - Herzzentrum
  • Bremen, Germany, 28277
    • Kardiologisch-Angiologische Praxis Herzzentrum Bremen
  • Dortmund, Germany, 44137
    • Kath. St. Paulus GmbH - Kardiologie
  • Dresden, Germany, 01307
    • Herzzentrum Dresden GmbH Universitätsklinik
  • Dresden, Germany, 01277
    • MVZ "Am Felsenkeller" (Dresden)
  • Düsseldorf, Germany, 40210
    • DaVita Clinical Research Deutschland GmbH
  • Elsterwerda, Germany, 04910
    • Zentrum fuer Klinische Studien Suedbrandenburg GmbH
  • Essen, Germany, 45147
    • Universitaetsklinikum Essen - Klinik für Kardiologie und Angiologie
  • Frankfurt am Main, Germany, 60590
    • Universitätsklinikum Frankfurt aM - Kardiologie
  • Friedrichshafen, Germany, 88048
    • Klinikum Friedrichshafen GmbH - Klinik für Kardiologie, Angiologie, Pneumologie und internistische Intensivmedizin
  • Göttingen, Germany, 37075
    • Universitätsmedizin Göttingen - Dept. Herzzentrum Göttingen
  • Homburg/Saar, Germany, 66424
    • UKS - Klinik für Pädiatrische Onkologie und Hämatologie
  • Jena, Germany, 07747
    • Universitätsklinikum Jena - Kardiologie
  • Kaiserslautern, Germany, 67655
    • Kardiopraxis Schirmer
  • Mainz, Germany, 55131
    • Universitätsmedizin Mainz, Kardiologie I, Studienzentrum
  • Mainz, Germany, 55131
    • Marienhaus Klinikum Mainz GmbH - Innere Medizin I
  • Mannheim, Germany, 68165
    • zero PRAXEN Mannheim-Schwetzingerstadt
  • München, Germany, 81675
    • Klinikum rechts der Isar TU München - Nephrologie
  • Tübingen, Germany, 72076
    • Universitätsklinikum Tübingen - Innere Medizin III Kardiologie und Angiologie
  • Warendorf, Germany, 48231
    • Josephs-Hospital Warendorf - Medizinische Klinik II
  • Wermsdorf, Germany, 04779
    • Al-Zoebi
  • Würzburg, Germany, 97078
    • Universitatsklinikum Würzburg - Zentrum für Herzinsuffizienz
  • Baden-Württemberg
    • Freiburg, Baden-Württemberg, Germany, 79106
      • Universitätsklinikum Freiburg Herzzentrum
    • Karlsbad, Baden-Württemberg, Germany, 76307
      • SRH Klinikum Karlsbad - Langensteinbach GmbH - Innere Medizin
  • EK Uni Lübeck
    • Lübeck, EK Uni Lübeck, Germany, 23562
      • Med. Universität Lübeck
• India
  • Jammu And Kashmir
    • Srinagar, Jammu And Kashmir, India, 190015
      • Gauri Heart Centre
  • Madhya Pradesh
    • Bhopal, Madhya Pradesh, India, 462016
      • Manoria Heart and Critical Care Hospital
  • Maharashtra
    • Nagpur, Maharashtra, India, 440010
      • Arneja Heart & Multispeciality Hospital
  • Punjab
    • Ludhiana, Punjab, India, 141001
      • Dayanand Medical College & Hospital
  • Tamil Nadu
    • Chennai, Tamil Nadu, India, 600037
      • The Madras Medical Mission
  • Uttarakhand
    • Dehradun, Uttarakhand, India, 248001
      • Shri Mahant Indiresh Hospital
  • West Bengal
    • Kolkata, West Bengal, India, 700054
      • Apollo Multispeciality Hospital, Kolkata
• Italy
  • Bergamo, Italy, 24127
    • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII
  • Brescia, Italy, 25123
    • University of Brescia
  • Caserta, Italy, 81100
    • AO S. Anna e S. Sebastiano
  • Cosenza, Italy, 87100
    • Presidio ospedaliero dell'annunziata
  • Genova, Italy, 16132
    • IRCCS Azienda Ospedaliero Universitaria San Martino - IST
  • Milano, Italy, 20162
    • ASST Grande Ospedale Metropolitano Niguarda
  • Milano, Italy, 20122
    • Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico
  • Napoli, Italy, 80131
    • Azienda Ospedaliera Universitaria Federico II Di Napoli
  • Napoli, Italy, 80100
    • AORN A. Cardarelli
  • Palermo, Italy, 90127
    • A.O.U. Policlinico Giaccone
  • Parma, Italy, 43126
    • Azienda Ospedaliera-Universitaria Parma
  • Perugia, Italy, 6129
    • AOU Perugia
  • Pisa, Italy, 56126
    • Fondazione Toscana G. Monastiero
  • Ragusa, Italy, 97100
    • ASP Ragusa
  • Reggio Emilia, Italy, 42123
    • Arcispedale S Maria Nuova Azienda ULSS-IRCCS
  • Roma, Italy, 154
    • Azienda Ospedaliera San Camillo Forlanini
  • Roma, Italy, 168
    • Fondazione Univ. Policlinico A.Gemelli
  • Sassari, Italy, 7100
    • AOU Sassari
  • Siena, Italy, 53100
    • Azienda Ospedaliera Universitaria Senese
  • Udine, Italy, 33100
    • Azienda Ospedaliera di Udine Ospedale S. Maria della Misericordia
  • Catanzaro
    • Germaneto, Catanzaro, Italy, 88100
      • Policlinico Mater Domini Università di Catanzaro
  • Genova
    • Lavagna, Genova, Italy, 16033
      • Ospedale del Tigullio ASL4 Liguria
  • Milan
    • San Donato Milanese, Milan, Italy, 20097
      • IRCCS Policlinico San Donato
  • Milano
    • Rozzano, Milano, Italy, 20089
      • Istituto Clinico Humanitas
    • Sesto San Giovanni, Milano, Italy, 20099
      • IRCCS MultiMedica
  • Torino
    • Rivoli, Torino, Italy, 10098
      • Complesso Ospedaliero "Nuovo Ospedale di Rivoli"
  • Venezia
    • Zelarino, Venezia, Italy, 30174
      • Ospedale dell'Angelo
• Korea, Republic of
  • Busan, Korea, Republic of, 49241
    • Pusan National University Hospital
  • Daegu, Korea, Republic of, 42601
    • Keimyung University Dongsan Hospital
  • Daegu, Korea, Republic of, 42472
    • Daegu Catholic Univ. Medical Center
  • Daejeon, Korea, Republic of, 35015
    • Chungnam national university hospital
  • Daejeon, Korea, Republic of, 361-711
    • Chungbuk National University Hospital
  • Gangwon-do, Korea, Republic of, 26426
    • Yonsei University Wonju Severance Christian Hospital
  • Gwangju, Korea, Republic of, 61469
    • Chonnam National University Hospital
  • Gyeonggi-Do, Korea, Republic of, 14068
    • Hallym University Sacred Heart Hospital
  • Gyeonggi-do, Korea, Republic of, 13620
    • Seoul National University Bundang Hospital
  • Seoul, Korea, Republic of, 03080
    • Seoul National University Hospital
  • Seoul, Korea, Republic of, 03722
    • Severance Hospital, Yonsei University Health System
  • Seoul, Korea, Republic of, 05505
    • Asan Medical Center
  • Seoul, Korea, Republic of, 02841
    • Korea University Anam Hospital
  • Seoul, Korea, Republic of, 08308
    • Korea University Guro Hospital
  • Seoul, Korea, Republic of, 06351
    • Samsung Medical Center
  • Seoul, Korea, Republic of, 03181
    • Kangbuk Samsung Hospital
  • Seoul, Korea, Republic of, 02447
    • Kyunghee University Medical Center
  • Seoul, Korea, Republic of, 06591
    • Seoul Saint Mary's Hospital
  • Timis
    • Incheon, Timis, Korea, Republic of, 405-220
      • Gachon University Gil Medical Center
• Norway
  • Bodø, Norway, 8005
    • Nordland Hospital Trust
  • Grålum, Norway, 1714
    • Sykehuset Østfold Kalnes
  • Oslo, Norway, 0369
    • Colosseumklinikken Medisinske Senter AS
  • Oslo, Norway, 424
    • Oslo universitetssykehus HF, Rikshospitalet
  • Skedsmokorset, Norway, 2020
    • Skedsmo Medisinske Senter, Norway
• Poland
  • Katowice, Poland, 40-530
    • Specjalistyczna Praktyka Lekarska s.c. Iwona Woźniak Skowerska Mariusz Skowerski
  • Lodz, Poland, 90-549
    • SPZOZ USK im. Wojskowej Akademii Medycznej UM w Łodzi - Centralny Szpital Weteranów
  • Oswiecim, Poland, 32-600
    • Medicome Sp. Z O.O.
  • Sopot, Poland, 81-852
    • NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog.
  • Szczecin, Poland, 71-434
    • Twoja Przychodnia-Szczecinskie Centrum Medyczne Sp. z o. o.
  • Tychy, Poland, 43-100
    • Polsko-Amerykanskie Kliniki Serca.American Heart of Poland Sp. z o.o.
  • Wroclaw, Poland, 53-114
    • 4 Wojskowy Szpital Kliniczny Z Poliklinika SP ZOZ
  • Pomorskie
    • Gdynia, Pomorskie, Poland, 81-157
      • Ind. Prak. Lek. w dziedz. Kardiologii lek. med. K. Cymerman
• Sweden
  • Danderyd, Sweden, 182 88
    • Danderyd Sjukhus
  • Jönköping, Sweden, 553 05
    • Medicinkliniken Ryhov
  • Karlstad, Sweden, 652 30
    • Centralsjukhuset Karlstad
  • Lund, Sweden, 22185
    • Skane University Hospital
  • Stockholm, Sweden, 171 64
    • Karolinska Universitetssjukhuset Solna,FOU Tema Hjärta Kärl
  • Stockholm, Sweden, 118 67
    • Sodersjukhuset AB
  • Uppsala, Sweden, 75185
    • Akademiska Sjukhuset Uppsala
  • Örebro, Sweden, 701 85
    • Universitetssjukhuset Orebro
• United Kingdom
  • West Sussex
    • Gatwick, West Sussex, United Kingdom, RH6 0PA
      • Master Centre for United Kingdom
• United States
  • California
    • Fremont, California, United States, 94538
      • Mission Cardiovascular Research Institute
  • Texas
    • McKinney, Texas, United States, 75071
      • Texas Institute of Cardiology PA

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Participants will be recruited from cardiology sites reflecting a real-world population of ASCVD and HF patients.

Description

Inclusion criteria:

1. Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study.
2. Age 18 years or above at the time of signing the informed consent.
3. Presence of ASCVD (atherosclerotic cardiovascular disease) and/or HF (heart failure)
4. Presence of serum creatinine in the medical chart within 24 months prior to signing of informed consent (for ASCVD patients only).

Exclusion criteria:

1. Previous participation in this study. Participation is defined as having given informed consent in this study.
2. Current participation (i.e., signed informed consent) in any other interventional clinical study.
3. Any hospitalization or unplanned visit within the last 60 days (including exacerbation of chronic disease with hospitalization).
4. Clinical evidence, or suspicion of, active infection within the last 60 days.
5. Mental incapacity, unwillingness, or language barriers precluding adequate understanding or cooperation

Study Plan

How is the study designed?

Number of groups / cohorts

4

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Atherosclerotic cardiovascular disease (ASCVD) with chronic kidney disease (CKD); electronic case report form (eGFR) below 60 ml/min/1.73m^2	Other: No treatment given; No treatment given
ASCVD without CKD; eGFR greater than or equal to 60 ml/min/1.73m^2	Other: No treatment given; No treatment given
HF with preserved ejection fraction (HFpEF) or HF with mildly reduced ejection fraction (HFmrEF)	Other: No treatment given; No treatment given
Heart failure (HF) with reduced ejection fraction (HFrEF)	Other: No treatment given; No treatment given

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
High sensitivity C-reactive protein (hsCRP) greater than or equal to 2 mg/L (yes/ no)	Count of patient	At visit (day 0)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Interleukin 6 (IL-6)	pg/ml	At visit (day 0)
N-terminal prohormone of brain natriuretic peptide (NT-proBNP)	pg/ml	At visit (day 0)

Collaborators and Investigators

• Sponsor: Novo Nordisk A/S
• Investigators: Study Director: Clinical Transparency (dept. 2834), Novo Nordisk A/S

Study record dates

Study Major Dates

• Study Start (Actual): November 23, 2023
• Primary Completion (Actual): April 30, 2025
• Study Completion (Actual): April 30, 2025

Study Registration Dates

• First Submitted: November 3, 2023
• First Submitted That Met QC Criteria: November 3, 2023
• First Posted (Actual): November 8, 2023

Study Record Updates

• Last Update Posted (Actual): May 9, 2025
• Last Update Submitted That Met QC Criteria: May 8, 2025
• Last Verified: May 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Urogenital Diseases; Pathologic Processes; Male Urogenital Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Heart Diseases; Chronic Disease; Disease Attributes; Renal Insufficiency; Heart Failure; Cardiovascular Diseases; Inflammation; Kidney Diseases; Renal Insufficiency, Chronic
• Other Study ID Numbers: NN6018-7527; U1111-1286-3420 (Other Identifier: World Health Organization (WHO))

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: According to the Novo Nordisk disclosure commitment on novonordisk-trials.com

Drug and device information, study documents

• Studies a U.S. FDA-regulated device product: No