Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery

June 13, 2026 updated by: Panalee Kittisopaporn, Prince of Songkla University

Investigation & Comparison of the Effects of Preoperative Nutritional Status Scores to Predict Post-op Pulmonary Complications Among Elderly Patients With Cardiac Surgery

This prospective study investigates prognostic values and compares the role of nutritional status by using GNRI, MNA-SF, PNI, and NAF in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In this prospective cohort study, 217 patients aged ≥60 years undergoing elective cardiac surgery at a tertiary university hospital were enrolled. Preoperative nutritional status was assessed using GNRI, MNA-SF, PNI, and NAF. The primary outcome was PPC occurrence during hospitalization. Predictive performance was evaluated using receiver operating characteristic (ROC) analysis, and multivariable logistic regression identified independent predictors

Study Type

Observational

Enrollment (Actual)

217

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Thailand
    • Changwat Songkhla
      • Hat Yai, Changwat Songkhla, Thailand, 90110
        • Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Elderly patients (aged ≥ 60 years old) who undergoing cardiac surgery in Songklanagarind hospital, Songkla, Thailand

Description

Inclusion Criteria:

  • Elderly patient age ≥ 60 years
  • Open heart surgical procedure on pump (CABG, valvular disease, combine CABG and valve surgery
  • Elective surgery

Exclusion Criteria:

- Emergency surgery

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
older patients
patients aged ≥60 years undergoing elective cardiac surgery
Other: Nutrition scoring systems
GNRI, MNA-SF, PNI, and NAF

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative pulmonary complication
Time Frame: 1 month
PPCs such as pneumonia, pulmonary embolism, ventilation longer than 24 h, pleural effusions necessitating drainage and reintubation within 72 h of extubation
1 month

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Prince of Songkla University

Investigators

  • Principal Investigator: Panalee Kittisopaporn, Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2024

Primary Completion (Actual)

April 30, 2026

Study Completion (Actual)

April 30, 2026

Study Registration Dates

First Submitted

March 25, 2024

First Submitted That Met QC Criteria

March 25, 2024

First Posted (Actual)

April 1, 2024

Study Record Updates

Last Update Posted (Actual)

June 16, 2026

Last Update Submitted That Met QC Criteria

June 13, 2026

Last Verified

March 1, 2024

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • REC.67-018-8-1

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

ethical considerations

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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