Prevalence of Thyroid Disorders in Patients With Immune Thrombocytopenic Purpura and Its Impact on Treatment

July 13, 2025 updated by: Ayah Ibrahim Nemr, Assiut University
Prevalence of thyroid disorders in patients with immune thrombocytopenic purpura and its impact on treatment

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

We investigate patients with ITP for screening of thyroid disorders and how to deal with it and effect of this on the ttt

Study Type

Observational

Enrollment (Estimated)

100

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

prospective cross sectional study

Description

Inclusion Criteria:

  • ITP patients will be classified as newly diagnosed, persistent and chronic based on duration less than 3 months, 3-12 months, and more than 12 months respectively.

    • refractory ITP patients.

Exclusion Criteria:

  • patients with history of thyroidectomy

    • patients with history of drug induced ITP
    • patients with history of HCV, HBV and HIV infection.
    • Patients who refuse to contribute in this study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Patients known ITP
Patients known ITP either newly diagnosed, chronic, refractory Age 18 yrs and above Patients with thyrodiectomy will not be in our study
Diagnostic test: Search for thyroid disorders
TSH , FT3 , FT4
Other Names:
  • Laboratory test
Diagnostic test: Laboratory test
Search for anti thyroid antibodies
Drug: Steroid and eltrombopage
See when we treat thyroid disorders, will patient respond to steroid or eltrombopage?
Other Names:
  • Drugs used in ITP

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Assess the frequency of thyroid disorders in patients with IT
Time Frame: Assess the frequency of thyroid disorders in patients with IT
Screening of thyroid disorders in patients with ITP
Assess the frequency of thyroid disorders in patients with IT
Evaluate the treatment of thyroid disorders in improvement in platelets count.
Time Frame: Evaluate the treatment of thyroid disorders in improvement in platelets count.
Evaluate if patients have managed according to thyroid disorders, will this affect in their response to ITP management
Evaluate the treatment of thyroid disorders in improvement in platelets count.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

July 1, 2025

Primary Completion (Estimated)

May 31, 2026

Study Completion (Estimated)

August 15, 2026

Study Registration Dates

First Submitted

June 10, 2025

First Submitted That Met QC Criteria

July 1, 2025

First Posted (Actual)

July 11, 2025

Study Record Updates

Last Update Posted (Actual)

July 17, 2025

Last Update Submitted That Met QC Criteria

July 13, 2025

Last Verified

July 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ITP and thyroid disorders

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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