Vibration Training for Patients With Chronic Stroke

April 23, 2026 updated by: CHIA-HUEI LIN, PhD

Effectiveness of Vibration Training on Muscle Strength, Functional Recovery, Quality of Life, and Self-Esteem in Patients With Chronic Stroke: A Randomized Controlled Trial

A 4-week program of vibration training in a seated position combined with conventional rehabilitation led to significant improvements in unaffected side lower limb muscle strength, functional recovery, quality of life, and self-esteem in patients with chronic stroke. No significant improvement was noted in affected side lower limb muscle strength. These findings highlight the integration of localized muscle vibration training into rehabilitation as a promising strategy for treating individuals with chronic stroke.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

39

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taipei, Taiwan
        • Division of Physical Medicine and Rehabilitation, Tri-Service General Hospital, National Defense Medical University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • hospitalization for chronic stroke (≥ 6 months since onset)
  • age ≥ 20 years
  • Mini-Mental State Examination score ≥ 24
  • able to communicate verbally or nonverbally and understand Mandarin or Taiwanese
  • modified Rankin Scale of 2 to 4
  • Brunnstrom stage ≥ 3
  • willing to participate with consent to randomization

Exclusion Criteria:

  • transient ischemic attack
  • neuromuscular or musculoskeletal disorders of the both upper or lower limbs or history of orthopedic surgery within the past 6 months
  • deep vein thrombosis
  • pacemaker implantation
  • unstable conditions, including cardiovascular disease, cancer, end-stage renal disease requiring hemodialysis, or psychiatric disorders

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: patients with chronic stroke underwent conventional rehabilitation plus vibration training
Device: vibration training
seated vibration training
No Intervention: patients with chronic stroke underwent conventional rehabilitation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
muscle strength measured by manual muscle test
Time Frame: From enrollment to the end of treatment at 4 weeks
From enrollment to the end of treatment at 4 weeks
functional recovery measured by Barthel index
Time Frame: From enrollment to the end of treatment at 4 weeks
From enrollment to the end of treatment at 4 weeks
functional recovery measured by Stroke Impact Scale
Time Frame: From enrollment to the end of treatment at 4 weeks
From enrollment to the end of treatment at 4 weeks

Secondary Outcome Measures

Outcome Measure
Time Frame
quality of life measured by short form 12 health survey
Time Frame: From enrollment to the end of treatment at 4 weeks
From enrollment to the end of treatment at 4 weeks
self-esteem measured by Rosenberg Self-Esteem Scale
Time Frame: From enrollment to the end of treatment at 4 weeks
From enrollment to the end of treatment at 4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

CHIA-HUEI LIN, PhD

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 18, 2023

Primary Completion (Actual)

March 31, 2025

Study Completion (Actual)

March 31, 2025

Study Registration Dates

First Submitted

January 12, 2026

First Submitted That Met QC Criteria

April 23, 2026

First Posted (Actual)

April 28, 2026

Study Record Updates

Last Update Posted (Actual)

April 28, 2026

Last Update Submitted That Met QC Criteria

April 23, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • A202305061

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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