Regional Innovation in Chronic Disease and Elderly Care

A Regional Integrated Care Innovation Program for Cardiometabolic Health, Pulmonary-Circulatory Disease Management, and Elderly Support

This project aims to develop a community-based health promotion intervention model for populations at potential risk of metabolic syndrome. Through exercise training and lifestyle modifications, the project seeks to improve cardiopulmonary function and disease control, align with current public health policies, and establish an evidence-based model with strong potential for broader implementation.

Study Overview

• Status: Recruiting
• Conditions: Hyperglycemia; Hypertension; Cardiovascular Disease; Hyperlipidemia

Detailed Description

Background： Hypertension, diabetes, and dyslipidemia are major risk factors for cardiovascular disease, with prevalence continuing to rise in Taiwan. These conditions are closely associated with shared risk factors such as aging, obesity, and smoking. The districts of Xinzhuang, Wugu, and Taishan in New Taipei City are densely populated and have a significant aging population. Environmental changes such as urbanization and air pollution pose threats to residents' cardiopulmonary health. Exercise interventions have been proven effective in improving blood pressure, blood glucose, and lipid profiles, as well as enhancing cardiopulmonary function and quality of life. Therefore, implementing structured and personalized exercise promotion programs in the community is of great importance for disease control and health promotion among populations with metabolic syndrome.

Methods： Participants will first undergo a one-month in-hospital conventional exercise training program, followed by an eleven-month home-based exercise intervention. During and after the intervention period, physical activity assessments and biochemical blood tests will be conducted.

Effect： This project aims to establish a community-based health promotion model for individuals at risk of hypertension, diabetes, and hyperlipidemia, centered on exercise interventions and lifestyle modifications. Through assessment, stratification, intervention, and outcome tracking, the project seeks to enhance health behaviors, self-management skills, and cardiopulmonary function in at-risk populations, thereby slowing disease progression and reducing healthcare resource utilization. The research findings will be submitted to relevant domestic and international academic conferences and SCI journals to increase Taiwan's international visibility in the fields of geriatric and "three highs" care. Additionally, the project will cultivate a new generation of healthcare professionals equipped with practical skills in preventive medicine and health promotion, strengthening interprofessional teamwork and community outreach capacity.

• Study Type: Observational
• Enrollment (Estimated): 1000

Contacts and Locations

• Study Contact: Name: Ke-Yun Chao, PhD; Phone Number: +886-905-301-879; Email: C00152@mail.fjuh.fju.edu.tw

Study Locations

• Taiwan
  • New Taipei City, Taiwan, 24352
    • Recruiting
    • Fu Jen Catholic University Hospital, Fu Jen Catholic University
    • Contact: Ke-Yun Chao, PhD; Phone Number: +886-905-301-879; Email: ck_qq@hotmail.con

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

patient of Affiliated University Hospital

Description

Inclusion Criteria:

• Participants with hypertension, hyperglycemia, or hyperlipidemia who meet at least one of these criteria are eligible for enrollment.

Exclusion Criteria:

• Age under 18 years
• Patients diagnosed with neuromuscular disorders
• Inability to perform cardiopulmonary exercise testing
• Refusal to participate in the study

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
appendicular skeletal muscle mass index	appendicular skeletal muscle mass (ASM) divided by height squared; low muscle mass is defined as ASMI < 7.0 kg/m² in men and < 5.7 kg/m² in women	From enrollment to the end of intervention at 12 months
six minute walk test	functional performance; higher scores mean a better outcome	From enrollment to the end of intervention at 12 months

Collaborators and Investigators

• Sponsor: Fu Jen Catholic University
• Investigators: Principal Investigator: Ke-Yun Chao, PhD, Fu Jen Catholic University

Study record dates

Study Major Dates

• Study Start (Actual): May 26, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026

Study Registration Dates

• First Submitted: April 27, 2026
• First Submitted That Met QC Criteria: May 4, 2026
• First Posted (Actual): May 11, 2026

Study Record Updates

• Last Update Posted (Actual): May 28, 2026
• Last Update Submitted That Met QC Criteria: May 26, 2026
• Last Verified: March 1, 2026

More Information

Terms related to this study

• Keywords: hypertension; cardiovascular disease; exercise training; hyperglycemia; hyperlipidemia
• Additional Relevant MeSH Terms: Vascular Diseases; Metabolic Diseases; Glucose Metabolism Disorders; Dyslipidemias; Lipid Metabolism Disorders; Nutritional and Metabolic Diseases; Hypertension; Cardiovascular Diseases; Hyperglycemia; Hyperlipidemias
• Other Study ID Numbers: FJUH114523

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No