Comparison of High-Intensity Interval Training With Moderate-Intensity Continuous Training in Chronic Non-Specific Low Back Pain Patients

June 10, 2026 updated by: Dr. Ariba Sohail (PT), Dow University of Health Sciences

Comparison of High-Intensity Interval Training With Moderate-Intensity Connuous Training In Chronic Non-Specific Low Back Pain Patients: Randomized Clinical Trial

The goal of this clinical trial is to compare the HIIT with MICT in chronic non-specific low back pain patients. The main questions it aims to answer are:

  • The broad aim of the study is to compare HIIT with MICT in pain reduction in chronic non-specific low back pain patients.
  • The purpose of this research is to compare HIIT with MICT on disability and quality of life among chronic non-specific low back pain patients.
  • It also attempts to investigate the relationship between the baseline attributes and outcome variables.

Researcher will compare the HIIT to MICT to see the effects on CNSLBP

Participants will be:

  • Allocated to HIIT or MICT group for 6 weeks.
  • Assessed pre and post intervention.
  • Continuously monitored during treatment sessions.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Referred patients of back pain persisting for > 12 weeks with no identifiable specific cause or underlying pathology from DUH OPD who meet the eligibility criteria.
  • Age group 20-48 with either gender.
  • NPRS score ranging between 3 and 5 (mild to moderate).
  • Modified ODI score is mild to moderate.

Exclusion Criteria:

  • Any client with a specific cause of LBP (neurological problems, fractures, malignancy, infections, or rheumatic diseases such as RA or ankylosing spondylitis).
  • Any client with cardiopulmonary problems (recent myocardial infarction, uncontrolled hypertension, asthma, COPD).
  • Any client with musculoskeletal disorders [injuries limiting exercises, spine injuries, recent trauma (fracture), scoliosis by Forward Adam's test].
  • Any client with metabolic conditions (thyroid problems, uncontrolled diabetes).
  • Pregnancy / first 3-6 months postpartum.
  • Recent surgery.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: High-Intensity Interval Training
A total of 40 participants will be enrolled in this group. Sessions will be conducted 3 times a week, each session lasting for 25 minutes. The duration breakdown is as follows: 3 minutes of warm-up, 6 bouts of HIIT (1 min of HIIT at 85-90% of HRmax, 2 min of recovery at 74-80% of HRmax), and 4 min of cool down. The intensity will be monitored using HR and the Borg Rating of Perceived Exertion. The mode of exercise will involve brisk walk and jog. At the end of each session, participants will perform 5-10 minutes stretching exercises targeting major muscle groups.
Other: Brisk walk and jog
High-Intensity Interval Training
Active Comparator: Moderate-Intensity Continuous Training
A total of 40 participants will be enrolled in this group. Sessions will be conducted 5 times a week, each session lasting for 46 minutes. The duration breakdown is as follows: 3 minutes of warm-up, 40 min of HIIT (at 60-70% of HRmax), and 3 min of cool down. The intensity will be monitored using HR and Borg Rating of Perceived Exertion. The mode of exercise will involve normal walk. At the end of each session, participants will perform 5-10 minutes stretching exercises targeting major muscle groups.
Other: Normal walk
Moderate-Intensity Continuous Training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Numeric Pain Rating Score (NPRS)
Time Frame: 6 weeks
Low back pain persisting for > 12 weeks with no identifiable specific cause or underlying pathology Score: Mild to moderate (3-5)
6 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Modified Oswestry Disability Index for disability
Time Frame: 6 weeks
Disability percentage derived from 10-item ODI scores 20-40% considered mild to moderate and eligible.
6 weeks
Short Form-12 for Quality of Life
Time Frame: 6 weeks
6 weeks
Modified Bruce Treadmill protocol for CV endurance
Time Frame: 6 weeks
6 weeks
Bioelectrical Impedance Analysis (BIA) for body composition
Time Frame: 6 weeks
6 weeks
height and weight for Body Mass Index
Time Frame: 6 weeks
6 weeks
Waist Hip Ratio for fat distribution
Time Frame: 6 weeks
6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Dow University of Health Sciences

Investigators

  • Principal Investigator: Ariba Sohail, Dow University of Health Sciences

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 14, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Study Registration Dates

First Submitted

June 5, 2026

First Submitted That Met QC Criteria

June 10, 2026

First Posted (Actual)

June 12, 2026

Study Record Updates

Last Update Posted (Actual)

June 12, 2026

Last Update Submitted That Met QC Criteria

June 10, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IRB-4535

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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