Comparison of High-Intensity Interval Training With Moderate-Intensity Continuous Training in Chronic Non-Specific Low Back Pain Patients
10 de junho de 2026 atualizado por: Dr. Ariba Sohail (PT), Dow University of Health Sciences
Comparison of High-Intensity Interval Training With Moderate-Intensity Connuous Training In Chronic Non-Specific Low Back Pain Patients: Randomized Clinical Trial
The goal of this clinical trial is to compare the HIIT with MICT in chronic non-specific low back pain patients. The main questions it aims to answer are:
- The broad aim of the study is to compare HIIT with MICT in pain reduction in chronic non-specific low back pain patients.
- The purpose of this research is to compare HIIT with MICT on disability and quality of life among chronic non-specific low back pain patients.
- It also attempts to investigate the relationship between the baseline attributes and outcome variables.
Researcher will compare the HIIT to MICT to see the effects on CNSLBP
Participants will be:
- Allocated to HIIT or MICT group for 6 weeks.
- Assessed pre and post intervention.
- Continuously monitored during treatment sessions.
Visão geral do estudo
Status
Recrutamento
Condições
Intervenção / Tratamento
Tipo de estudo
Intervencional
Inscrição (Estimado)
80
Estágio
- Não aplicável
Contactos e Locais
Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.
Contato de estudo
- Nome: Ariba Dr. Ariba Sohail (PT)
- Número de telefone: +923480218683
- E-mail: aribasohail123@gmail.com
Locais de estudo
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Karachi, Paquistão
- Recrutamento
- Dr. Ariba Sohail (PT)
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Contato:
- Ariba Sohail
- Número de telefone: +923480218683
- E-mail: aribasohail123@gmail.com
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Critérios de participação
Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.
Critérios de elegibilidade
Idades elegíveis para estudo
- Adulto
Aceita Voluntários Saudáveis
Não
Descrição
Inclusion Criteria:
- Referred patients of back pain persisting for > 12 weeks with no identifiable specific cause or underlying pathology from DUH OPD who meet the eligibility criteria.
- Age group 20-48 with either gender.
- NPRS score ranging between 3 and 5 (mild to moderate).
- Modified ODI score is mild to moderate.
Exclusion Criteria:
- Any client with a specific cause of LBP (neurological problems, fractures, malignancy, infections, or rheumatic diseases such as RA or ankylosing spondylitis).
- Any client with cardiopulmonary problems (recent myocardial infarction, uncontrolled hypertension, asthma, COPD).
- Any client with musculoskeletal disorders [injuries limiting exercises, spine injuries, recent trauma (fracture), scoliosis by Forward Adam's test].
- Any client with metabolic conditions (thyroid problems, uncontrolled diabetes).
- Pregnancy / first 3-6 months postpartum.
- Recent surgery.
Plano de estudo
Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.
Como o estudo é projetado?
Detalhes do projeto
- Finalidade Principal: Tratamento
- Alocação: Randomizado
- Modelo Intervencional: Atribuição Paralela
- Mascaramento: Dobro
Armas e Intervenções
Grupo de Participantes / Braço |
Intervenção / Tratamento |
|---|---|
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Experimental: High-Intensity Interval Training
A total of 40 participants will be enrolled in this group.
Sessions will be conducted 3 times a week, each session lasting for 25 minutes.
The duration breakdown is as follows: 3 minutes of warm-up, 6 bouts of HIIT (1 min of HIIT at 85-90% of HRmax, 2 min of recovery at 74-80% of HRmax), and 4 min of cool down.
The intensity will be monitored using HR and the Borg Rating of Perceived Exertion.
The mode of exercise will involve brisk walk and jog.
At the end of each session, participants will perform 5-10 minutes stretching exercises targeting major muscle groups.
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High-Intensity Interval Training
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Comparador Ativo: Moderate-Intensity Continuous Training
A total of 40 participants will be enrolled in this group.
Sessions will be conducted 5 times a week, each session lasting for 46 minutes.
The duration breakdown is as follows: 3 minutes of warm-up, 40 min of HIIT (at 60-70% of HRmax), and 3 min of cool down.
The intensity will be monitored using HR and Borg Rating of Perceived Exertion.
The mode of exercise will involve normal walk.
At the end of each session, participants will perform 5-10 minutes stretching exercises targeting major muscle groups.
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Moderate-Intensity Continuous Training
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O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Numeric Pain Rating Score (NPRS)
Prazo: 6 weeks
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Low back pain persisting for > 12 weeks with no identifiable specific cause or underlying pathology Score: Mild to moderate (3-5)
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6 weeks
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Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Modified Oswestry Disability Index for disability
Prazo: 6 weeks
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Disability percentage derived from 10-item ODI scores 20-40% considered mild to moderate and eligible.
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6 weeks
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Short Form-12 for Quality of Life
Prazo: 6 weeks
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6 weeks
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Modified Bruce Treadmill protocol for CV endurance
Prazo: 6 weeks
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6 weeks
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Bioelectrical Impedance Analysis (BIA) for body composition
Prazo: 6 weeks
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6 weeks
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height and weight for Body Mass Index
Prazo: 6 weeks
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6 weeks
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Waist Hip Ratio for fat distribution
Prazo: 6 weeks
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6 weeks
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Colaboradores e Investigadores
É aqui que você encontrará pessoas e organizações envolvidas com este estudo.
Patrocinador
Investigadores
- Investigador principal: Ariba Sohail, Dow University of Health Sciences
Publicações e links úteis
A pessoa responsável por inserir informações sobre o estudo fornece voluntariamente essas publicações. Estes podem ser sobre qualquer coisa relacionada ao estudo.
Publicações Gerais
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- Cheak-Zamora NC, Wyrwich KW, McBride TD. Reliability and validity of the SF-12v2 in the medical expenditure panel survey. Qual Life Res. 2009 Aug;18(6):727-35. doi: 10.1007/s11136-009-9483-1. Epub 2009 May 8.
- da Silva T, Mills K, Brown BT, Pocovi N, de Campos T, Maher C, Hancock MJ. Recurrence of low back pain is common: a prospective inception cohort study. J Physiother. 2019 Jul;65(3):159-165. doi: 10.1016/j.jphys.2019.04.010. Epub 2019 Jun 14.
- Sheahan PJ, Nelson-Wong EJ, Fischer SL. A review of culturally adapted versions of the Oswestry Disability Index: the adaptation process, construct validity, test-retest reliability and internal consistency. Disabil Rehabil. 2015;37(25):2367-74. doi: 10.3109/09638288.2015.1019647. Epub 2015 Mar 4.
- Verbrugghe J, Agten A, Stevens S, Hansen D, Demoulin C, O Eijnde B, Vandenabeele F, Timmermans A. Exercise Intensity Matters in Chronic Nonspecific Low Back Pain Rehabilitation. Med Sci Sports Exerc. 2019 Dec;51(12):2434-2442. doi: 10.1249/MSS.0000000000002078.
- Cerini T, Hilfiker R, Riegler TF, Felsch QTM. 12 weeks high intensity interval training versus moderate intensity continuous training in chronic low back pain subjects: a randomised single-blinded feasibility study. Arch Physiother. 2022 May 2;12(1):12. doi: 10.1186/s40945-022-00136-3.
- Atakan MM, Guzel Y, Bulut S, Kosar SN, McConell GK, Turnagol HH. Six high-intensity interval training sessions over 5 days increases maximal oxygen uptake, endurance capacity, and sub-maximal exercise fat oxidation as much as 6 high-intensity interval training sessions over 2 weeks. J Sport Health Sci. 2021 Jul;10(4):478-487. doi: 10.1016/j.jshs.2020.06.008. Epub 2020 Jun 18.
- Shokri P, Zahmatyar M, Falah Tafti M, Fathy M, Rezaei Tolzali M, Ghaffari Jolfayi A, Nejadghaderi SA, Sullman MJM, Kolahi AA, Safiri S. Non-spinal low back pain: Global epidemiology, trends, and risk factors. Health Sci Rep. 2023 Sep 4;6(9):e1533. doi: 10.1002/hsr2.1533. eCollection 2023 Sep.
- Fernandez-Rodriguez R, Alvarez-Bueno C, Cavero-Redondo I, Torres-Costoso A, Pozuelo-Carrascosa DP, Reina-Gutierrez S, Pascual-Morena C, Martinez-Vizcaino V. Best Exercise Options for Reducing Pain and Disability in Adults With Chronic Low Back Pain: Pilates, Strength, Core-Based, and Mind-Body. A Network Meta-analysis. J Orthop Sports Phys Ther. 2022 Aug;52(8):505-521. doi: 10.2519/jospt.2022.10671. Epub 2022 Jun 19.
- Custers P, Van de Kelft E, Eeckhaut B, Sabbe W, Hofman A, Debuysscher A, Van Acker G, Maes G. Clinical Examination, Diagnosis, and Conservative Treatment of Chronic Low Back Pain: A Narrative Review. Life (Basel). 2024 Aug 29;14(9):1090. doi: 10.3390/life14091090.
- 35. Mikat, RP. Validity And Reliability of Waist-To-Hip Ratio Measurements From Dual Digital-Photograph Anthropometry. Medicine & Science in Sports & Exercise. May 2001. 33(5):p S241.
- Shirai Y, Momosaki R, Kokura Y, Kato Y, Okugawa Y, Shimizu A. Validation of Asian Body Mass Index Cutoff Values for the Classification of Malnutrition Severity According to the Global Leadership Initiative on Malnutrition Criteria in Patients with Chronic Obstructive Pulmonary Disease Exacerbations. Nutrients. 2022 Nov 10;14(22):4746. doi: 10.3390/nu14224746.
- 26. Weir CB, Jan A. BMI Classification Percentile and Cut off Points [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541070/
- 25. Kauser S, Ahmed B, Aslam S. Effects of Moderate Intensity Continuous Training on Body Composition and Aerobic Fitness in Female College Students. Vol. 6, The Sky-International Journal of Physical Education and Sports Sciences.
- 23. Amir R, Jehangir F, Muhammad M, Ahsan NJ, Adnan T. Frequency and Determinants of Chronic Lower Back Pain Among Patients Presenting To Primary Care Clinics in Pakistan: A Cross-Sectional Analysis. Journal of Rawalpindi Medical College. 2023 Dec 30;27(4).
- 21. Sarfraz M, Shadmehr A, Naz E, Ali M, Rahim A. Comparison of Short-Term Effects of High-Intensity Interval Training vs Moderate Intensity Continuous Training on Anthropometric Characteristics of Overweight Young Women. Pakistan Journal of Medical and Health Sciences. 2022 Aug 31;16(8):729-32.
- Berge J, Hjelmesaeth J, Hertel JK, Gjevestad E, Smastuen MC, Johnson LK, Martins C, Andersen E, Helgerud J, Storen O. Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity-A Randomized Controlled Trial. Obesity (Silver Spring). 2021 Feb;29(2):359-369. doi: 10.1002/oby.23078.
- D'Amuri A, Sanz JM, Capatti E, Di Vece F, Vaccari F, Lazzer S, Zuliani G, Dalla Nora E, Passaro A. Effectiveness of high-intensity interval training for weight loss in adults with obesity: a randomised controlled non-inferiority trial. BMJ Open Sport Exerc Med. 2021 Jul 20;7(3):e001021. doi: 10.1136/bmjsem-2020-001021. eCollection 2021.
- 18. Uysal HŞ, Korkmaz S, Aksakallı O. The effect of six-week bodyweight high-intensity interval training on the performance of young female athletes. Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2024 May 2;12(1):15-25.
- 17. Dregney TM, Thul CM, Linde JA, Lewis BA. Affective responses to high-intensity interval training relative to moderate-intensity continuous training. Physical Activity and Health. 2023;7(1):229-38.
- Poon ET, Chan KW, Wongpipit W, Sun F, Wong SH. Acute Physiological and Perceptual Responses to Whole-Body High-Intensity Interval Training Compared with Equipment-Based Interval and Continuous Training. J Sports Sci Med. 2023 Sep 1;22(3):532-540. doi: 10.52082/jssm.2023.532. eCollection 2023 Sep.
- 15. Tanaka K, Matsuo T. Global trends in high-intensity interval training (HIIT). The Journal of Physical Fitness and Sports Medicine. 2021 May 25;10(3):127-8.
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- 13. Kabir MS, Yadav S, Biswas S, Pradhan S, Geantă VA. Aerobic VS Anaerobic Exercise on Body Composition and Hormonal Adaptations in Athletes and Non-Athletes: A Randomized Controlled Trial. Journal of Coaching and Sports Science [Internet]. 2025 Jan 27;4(1):52-65. Available from: https://journal.foundae.com/index.php/jcss/article/view/553
- Verbrugghe J, Hansen D, Demoulin C, Verbunt J, Roussel NA, Timmermans A. High Intensity Training Is an Effective Modality to Improve Long-Term Disability and Exercise Capacity in Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial. Int J Environ Res Public Health. 2021 Oct 14;18(20):10779. doi: 10.3390/ijerph182010779.
- van Eetvelde JS, Timmermans AAA, Coninx K, Kempeneers K, Meeus M, Marneffe W, Meus T, Meuwissen I, Roussel NA, Stassijns G, Verbrugghe J. Technology supported High Intensity Training in chronic non-specific low back pain (the Techno-HIT trial): study protocol of a randomised controlled trial. BMJ Open Sport Exerc Med. 2024 Oct 7;10(4):e002180. doi: 10.1136/bmjsem-2024-002180. eCollection 2024.
- Verbrugghe J, Agten A, Stevens S, Hansen D, Demoulin C, Eijnde BO, Vandenabeele F, Timmermans A. High Intensity Training to Treat Chronic Nonspecific Low Back Pain: Effectiveness of Various Exercise Modes. J Clin Med. 2020 Jul 27;9(8):2401. doi: 10.3390/jcm9082401.
- Pinho H, Neves M, Costa F, Silva AG. Pain intensity and pain sensitivity are not increased by a single session of high-intensity interval aerobic exercise in individuals with chronic low back pain: A randomized and controlled trial. Musculoskelet Sci Pract. 2023 Aug;66:102824. doi: 10.1016/j.msksp.2023.102824. Epub 2023 Jul 4.
- 4. Aziz R, Niaz M, Ashraf A, Pari S, Ali R. Prevalence of Work Related Low Back Pain Among Clinical Physical Therapists. Vol. 15. 2021.
- Momen Majumder MS, Hakim F, Bandhan IH, Razzaque MA, Zahid-Al-Quadir A, Ahmed S, Choudhury MR, Haq SA, Zaman MM. Low back pain in the Bangladeshi adult population: a cross-sectional national survey. BMJ Open. 2022 Sep 8;12(9):e059192. doi: 10.1136/bmjopen-2021-059192.
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Datas de registro do estudo
Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.
Datas Principais do Estudo
Início do estudo (Real)
14 de maio de 2026
Conclusão Primária (Estimado)
1 de dezembro de 2026
Conclusão do estudo (Estimado)
1 de dezembro de 2026
Datas de inscrição no estudo
Enviado pela primeira vez
5 de junho de 2026
Enviado pela primeira vez que atendeu aos critérios de CQ
10 de junho de 2026
Primeira postagem (Real)
12 de junho de 2026
Atualizações de registro de estudo
Última Atualização Postada (Real)
12 de junho de 2026
Última atualização enviada que atendeu aos critérios de controle de qualidade
10 de junho de 2026
Última verificação
1 de junho de 2026
Mais Informações
Termos relacionados a este estudo
Palavras-chave
Termos MeSH relevantes adicionais
Outros números de identificação do estudo
- IRB-4535
Plano para dados de participantes individuais (IPD)
Planeja compartilhar dados de participantes individuais (IPD)?
NÃO
Informações sobre medicamentos e dispositivos, documentos de estudo
Estuda um medicamento regulamentado pela FDA dos EUA
Não
Estuda um produto de dispositivo regulamentado pela FDA dos EUA
Não
Essas informações foram obtidas diretamente do site clinicaltrials.gov sem nenhuma alteração. Se você tiver alguma solicitação para alterar, remover ou atualizar os detalhes do seu estudo, entre em contato com register@clinicaltrials.gov. Assim que uma alteração for implementada em clinicaltrials.gov, ela também será atualizada automaticamente em nosso site .