- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07645963
Effects of Myofascial Trigger Point Release Versus Neil Asher Technique Oin Patients With Rotator Cuff Syndrome
Effects of Myofascial Trigger Point Release Versus Neil Asher Technique on Pain, Range of Motion, and Disability in Patients With Rotator Cuff Syndrome
Study Overview
Status
Conditions
Detailed Description
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Samrood Akram, PhD*
- Phone Number: 03324806143
- Email: samrood.akram@riphah.edu.pk
Study Locations
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Punjab Province
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Lahore, Punjab Province, Pakistan, 54000
- University of Lahore Teaching Hospital, Lahore HOD Physio Department
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Age 40-60 years
- Positive Neer's and Hawkins Kennedy test (27)
- Grade 1 or 2 rotator cuff syndrome (non-surgical)
Exclusion Criteria:
- Cardiac issues (e.g., myocardial infarction)
- Fibromyalgia
- Pregnancy
- Trauma-related shoulder pain
- History of shoulder surgery
- Numbness, tingling
- Corticosteroid injections
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
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Experimental: Myofascial Trigger Point Release (MFTR)+ conservative physiotherapy Group)
This group will be given Myofascial Trigger Point Release (MFTR) with basic physiotherapy care.
|
lateral border of the scapula, just below the infraspinatus. • Compression is followed by horizontal abduction and external rotation to stretch the muscle. Ischemic Compression: Each active trigger point is treated with 2 sets of deep pressure, applied using the therapist's fingers, thumb, or elbow. Duration: Each compression lasts 20-30 seconds, gradually increasing pressure to the patient's tolerance. Post-Compression Stretching: Gentle passive stretching of the treated muscle follows immediately after each compression set to restore muscle length. Each session will last 35 minutes (5 minutes hot pack, 10 minutes stretching, 20 minutes Myofascial Trigger Point Release) |
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Active Comparator: Neil Asher Technique (NAT) + conservative physiotherapy Group
This group will be given Neil Asher Technique (NAT) along with basic physiotherapy care.
|
The NAT is a non-invasive trigger point therapy that applies a specific sequence of ischemic compressions to deactivate active trigger points, stimulate reflex responses, and promote muscular balance. Apply several deep strokes over the fibrous band and then each trigger point is treated with sustained manual pressure for 20-30 seconds, repeated 2-3 times per session. Hot Pack Application: A moist hot pack will be applied over the affected shoulder for 5 minutes using a protective towel. Shoulder Stretching Routine: Includes flexion/extension, abduction/adduction, and internal/external rotation (each stretch held for 20-30 seconds and repeated 3-5 times). |
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Numeric Pain Rating Scale (NPRS) - Pain Assessment
Time Frame: upto 4 weeks
|
The Numeric Pain Rating Scale (NPRS) is a unidimensional, patient-reported outcome measure used to assess pain intensity.
Participants are asked to rate their current pain level, or average pain over a specified recall period (e.g., past 24 hours or past week), using an 11-point scale ranging from 0 to 10, where 0 indicates "no pain" and 10 indicates "worst imaginable pain."
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upto 4 weeks
|
|
Universal Goniometer (UG) - Range of Motion (ROM)
Time Frame: upto 4 weeks
|
The Universal Goniometer (UG) is a standard clinical instrument used for measuring joint range of motion (ROM) in degrees. It consists of a fulcrum, stationary arm, and movable arm, allowing precise angular measurement of joint movement. For ROM assessment, the participant is positioned according to standardized protocols (supine, prone, or sitting depending on the joint being assessed). Anatomical landmarks are used for alignment to ensure accuracy and reliability. The stationary arm is aligned with the proximal segment of the joint, while the movable arm follows the distal segment. |
upto 4 weeks
|
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Shoulder Pain and Disability Index (SPADI) - Disability Outcome
Time Frame: upto 4 weeks
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The Shoulder Pain and Disability Index (SPADI) is a validated, self-administered questionnaire designed to measure pain and functional disability in patients with shoulder conditions. It consists of 13 items divided into two subscales: Pain subscale (5 items) - assesses severity of shoulder pain during specific activities Disability subscale (8 items) - assesses difficulty in performing functional tasks such as dressing, reaching, lifting, and carrying objects Each item is scored on a Visual Analog Scale (0-10), where higher scores indicate greater pain and disability. The total SPADI score is calculated as a percentage, with 0% representing no disability and 100% representing maximum disability. |
upto 4 weeks
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Iqra Nazir, MSPT*, Riphah International University
Publications and helpful links
General Publications
- Zhao J, Luo M, Pan J, Liang G, Feng W, Zeng L, Yang W, Liu J. Risk factors affecting rotator cuff retear after arthroscopic repair: a meta-analysis and systematic review. J Shoulder Elbow Surg. 2021 Nov;30(11):2660-2670. doi: 10.1016/j.jse.2021.05.010. Epub 2021 Jun 2.
- Varacallo MA, El Bitar Y, Sina RE, Mair SD. Rotator Cuff Syndrome. 2024 Mar 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK531506/
- Kuhn JE. Prevalence, natural history, and nonoperative treatment of rotator cuff disease. Operative techniques in sports medicine. 2023;31(1):150978.
- Meyers AR, Wurzelbacher SJ, Krieg EF, Ramsey JG, Crombie K, Christianson AL, Luo L, Burt S. Work-Related Risk Factors for Rotator Cuff Syndrome in a Prospective Study of Manufacturing and Healthcare Workers. Hum Factors. 2023 May;65(3):419-434. doi: 10.1177/00187208211022122. Epub 2021 Jun 20.
- Zahra T, Altaf F, Akhtar H, Awan SS, Sher UA, Waris S. Sleep Quality and Nocturnal Pain in Patients of Rotator Cuff Syndrome. Pakistan Journal of Medical & Health Sciences. 2022;16(09):394-.
- Kwan CK, Ko MC, Fu SC, Leong HT, Ling SK, Oh JH, Yung PS. Are muscle weakness and stiffness risk factors of the development of rotator cuff tendinopathy in overhead athletes: a systematic review. Ther Adv Chronic Dis. 2021 Jul 3;12:20406223211026178. doi: 10.1177/20406223211026178. eCollection 2021.
- Sidiropoulos K, Samundeeswari S, Giannatos V, Kotsapas M, Arrigoni P, Montoya F, Brilakis E, Latz D, Koukos C. Partial Cuff Repair in Rotator Cuff Tears: Current Concepts and Clinical Considerations. Indian J Orthop. 2025 Feb 4;59(6):743-755. doi: 10.1007/s43465-025-01338-0. eCollection 2025 Jun.
- Giri A, O'Hanlon D, Jain NB. Risk factors for rotator cuff disease: A systematic review and meta-analysis of diabetes, hypertension, and hyperlipidemia. Ann Phys Rehabil Med. 2023 Feb;66(1):101631. doi: 10.1016/j.rehab.2022.101631. Epub 2022 Nov 30.
- Khadour FA, Khadour YA, Alharbi NSK, Alhatem W, Albarroush D, Dao X. Risk factors for rotator cuff tear in Syrian adults: a cross-sectional study. Sci Rep. 2025 Feb 18;15(1):5837. doi: 10.1038/s41598-025-89878-1.
- Javed O, Maldonado KA, Ashmyan R. Anatomy, Shoulder and Upper Limb, Muscles. 2023 Jul 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK482410/
- Cao Z, Li Q, Li Y, Wu J. The association of metabolic syndrome with rotator cuff tendinopathy: a two-sample Mendelian randomization study. Diabetol Metab Syndr. 2023 Oct 24;15(1):211. doi: 10.1186/s13098-023-01189-5.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- REC/RCR&AHS/25/0116 Iqra
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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