Deuterium Labelled Carbohydrate Oxidation During High Intensity Exercise (D7 glucose ox)

June 9, 2026 updated by: Javier Gonzalez, University of Bath
The aim of the current project is to use deuterium-labelled glucose to assess exogenous glucose oxidation rates during exercise at moderate and high intensity.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

6

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United Kingdom
    • Bath
      • Bath, Bath, United Kingdom, BA2 7AY
        • University of Bath

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Endurance trained
  • Aged 18 to 65 years

Exclusion Criteria:

  • Contraindications to exercise
  • Unable to complete 2 hours of continuous cycling

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Glucose
Glucose ingestion durign exercise at 90 g.h labelled with U13C and D7 glucose.
Other: glucose
Glucose ingestion at 90 g/h labelled with U13C and D7 glucose

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Total exogenous glucose oxidation rate
Time Frame: Measured over 120 mins
Total exogenous glucose oxidation rate (g/h)
Measured over 120 mins

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Exogenous glucose oxidation rate during moderate intensity exercise
Time Frame: 90 minutes
Exogenous glucose oxidation rate during moderate intensity exercise (g/h)
90 minutes
Exogenous glucose oxidation rate during high intensity exercise
Time Frame: 30 minutes
Exogenous glucose oxidation rate during high intensity exercise (g/h)
30 minutes

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Blood glucose concentrations
Time Frame: 120 minutes
Blood glucose concentrations (mmol/L)
120 minutes
Blood lactate concentrations
Time Frame: 120 minutes
Blood lactate concentrations (mmol/L)
120 minutes
Blood bicarbonate concentrations
Time Frame: 120 minutes
Blood bicarbonate concentrations (mmol/L
120 minutes
Blood pCO2
Time Frame: 120 minutes
Blood pCO2 (mmHg)
120 minutes
Oxygen consumption rate
Time Frame: 120 minutes
Oxygen consumption rate (L/min)
120 minutes
Carbon dioxide production rate
Time Frame: 120 minutes
Carbon dioxide production rate (L/min)
120 minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Bath

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 8, 2026

Primary Completion (Estimated)

July 30, 2026

Study Completion (Estimated)

September 30, 2026

Study Registration Dates

First Submitted

June 9, 2026

First Submitted That Met QC Criteria

June 9, 2026

First Posted (Actual)

June 15, 2026

Study Record Updates

Last Update Posted (Actual)

June 15, 2026

Last Update Submitted That Met QC Criteria

June 9, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 16515-20228

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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