- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07662837
Effects of Tai Chi Therapy Versus Qi-Gong in Stage-I Parkinson's Patients.
August 25, 2026 updated by: Lahore University of Biological and Applied Sciences
Effects of Tai Chi Therapy Versus Qi-Gong on Postural Control, Functional Balance , and Motor Function in Stage-I Parkinson's Patients.
This study has important clinical, academic, and practical relevance in neuromuscular rehabilitation.
Clinically, it aims to identify effective and tolerable rehabilitation strategies for individuals with Parkinson's disease by comparing Tai Chi Therapy with Qi-Gong there by supporting evidence-based physiotherapy practice and improving patient adherence.
Academically, it contributes to the limited literature on comparative effectiveness of these interventions and incorporates patient-centered outcomes such as exercise perception, which are often underreported.
From a practical and societal perspective, identifying a more acceptable and effective approach may enhance long-term participation in rehabilitation, potentially slow disease progression, and reduce the overall healthcare burden associated with Parkinson's disease.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
Parkinson's disease is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, leading to motor symptoms such as tremor, rigidity, bradykinesia, and postural instability.
The title of the present study focuses on evaluating the effectiveness of Tai Chi Therapy versus Qi-Gong on Postural Control, Functional Balance and Motor Function in individuals with Stage-I with Parkinson's disease.
The study design is a randomized controlled trial with participants allocated into two groups.
The study duration is expected to span 8 to 12 weeks, allowing sufficient time for neuromuscular adaptations and observable functional improvements while maintaining feasibility and participant compliance.
Outcome measures include standardized and validated tools such as the Unified Parkinson's Disease Rating Scale for assessing disease severity, the Berge Balance Scale is use for the functional balance and postural control these measures are recorded at baseline and post-intervention to determine the effectiveness of the rehabilitation protocol, providing comprehensive insight into motor Motor Control, Functional Balance and Motor Function in individuals with Stage I Parkinson's disease.
Study Type
Interventional
Enrollment (Estimated)
50
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Maryam Fayyaz
- Phone Number: 03374677916
- Email: maryamfayyazawan@gmail.com
Study Contact Backup
- Name: Salwa Atta
- Phone Number: 03084579229
Study Locations
-
-
-
Lahore, Pakistan
- Recruiting
- The Meer's Physiotherapy and Rehabilitation
-
Contact:
- Salwa Atta
- Phone Number: 03084579229
- Email: salwa.atta@ubas.edu.pk
-
-
Punjab Province
-
Lahore, Punjab Province, Pakistan
- Recruiting
- Ghurki Trust and Teaching Hospital
-
Contact:
- Dr. Mir Shakeel Ahmad
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- Diagnosis of PD based on the Hoehn & Yahr staging system (Stages I).
- Male or female patients aged between 50-65 years.
- Currently receiving stable anti-Parkinsonian medication, with no changes in the treatment regimen for at least 3 months.
- Basic self-care ability with no severe cognitive impairment (Mini-Mental State Examination [MMSE] score ≥24).
Exclusion Criteria:
- Depression, as assessed based on a score of >16 for the Beck Depression Inventory-II (BDI-II).
- Recent deep brain stimulation (DBS) treatment.
- Use of medication that interferes with cognition, alertness, or attention.
- Current participation in an exercise training program.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Tai Chi
Tai Chi is a traditional Chinese "moving meditation" that combines slow, gentle movements with deep diaphragmatic breathing and focused attention.
It is designed to cultivate inner energy and harmonize mind and body, making it a popular low-impact, therapeutic exercise.
|
Group A will receive 8 weeks of standard conventional physical therapy plus Tai Chi (40 min of Tai Chi and 20 min of conventional physical therapy) total duration of session will be 60 minutes.
The most commonly applied Tai Chi style will be Yang style.
|
|
Experimental: Qi Gong
It is a holistic, low-impact mind-body practice that combines slow, flowing movements, deep rhythmic breathing, and focused intention to balance energy flow, improve health, and enhance overall vitality.
|
Group B will receive 8 weeks of standard conventional physical therapy (20 minutes) plus Health Qigong Baduanjin and wuqinxi ( 40 minutes) with total duration of 60 minutes, 2 times a week each pattern for 8 weeks.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Unified Parkinson's Disease Rating Scale
Time Frame: 8-12 weeks
|
It will be used for motor function.
UPDRS shows high ICCs like 0.90 for Motor, 0.85 for ADL).A higher score indicates greater motor impairment and disease severity.
Total score is 108 across 27 items.
It will be used at pre and post intervention.
|
8-12 weeks
|
|
Berg Balance Scale (BBS)
Time Frame: 8-12 weeks
|
The Berg Balance Scale (BBS) is a widely used clinical test with 14 functional tasks (like sitting, standing, reaching, turning) to measure static and dynamic postural control and functional balance, primarily to assess fall risk in older adults and neurological patients (stroke, Parkinson's).
It scores tasks from 0 (unable) to 4 (independent) for a total of 56, with lower scores indicating higher fall risk, helping therapists plan interventions.
It Shows very high intra-rater (same tester) and inter-rater (different testers) reliability, with Intraclass Correlation Coefficients (ICC) often around 0.97-0.99.
The Berg Balance Scale have 14-item.
Each item is scored on a 0-4 scale, with a total score of 56 points indicating no balance deficit and lower scores correlating with higher fall risk.
The patients with the scores between 0-20 have High fall risk (may need wheelchair), 21-40: Medium fall risk (may need cane/walker) and 41-56: Low fall risk (independent mobility).
|
8-12 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Study Director: Salwa Atta, Lahore University of Biological & Applied Sciences
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Xu F, Soh KG, Chan YM, Bai XR, Qi F, Deng N. Effects of tai chi on postural balance and quality of life among the elderly with gait disorders: A systematic review. PLoS One. 2023 Sep 28;18(9):e0287035. doi: 10.1371/journal.pone.0287035. eCollection 2023.
- Song R, Grabowska W, Park M, Osypiuk K, Vergara-Diaz GP, Bonato P, Hausdorff JM, Fox M, Sudarsky LR, Macklin E, Wayne PM. The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson's disease: A systematic review and meta-analysis. Parkinsonism Relat Disord. 2017 Aug;41:3-13. doi: 10.1016/j.parkreldis.2017.05.019. Epub 2017 May 25.
- Fidan O, Seyyar GK, Aras B, Colak E, Aras O. The effect of Tai Chi and Qigong on health-related quality of life in Parkinson's disease: a systematic review and meta-analysis of systematic reviews. Int J Rehabil Res. 2019 Sep;42(3):196-204. doi: 10.1097/MRR.0000000000000358.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 30, 2026
Primary Completion (Estimated)
August 30, 2026
Study Completion (Estimated)
October 10, 2026
Study Registration Dates
First Submitted
June 17, 2026
First Submitted That Met QC Criteria
June 17, 2026
First Posted (Actual)
June 23, 2026
Study Record Updates
Last Update Posted (Actual)
August 26, 2026
Last Update Submitted That Met QC Criteria
August 25, 2026
Last Verified
August 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Synucleinopathies
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Neurodegenerative Diseases
- Movement Disorders
- Parkinsonian Disorders
- Basal Ganglia Diseases
- Parkinson Disease
- Therapeutics
- Mind-Body Therapies
- Complementary Therapies
- Exercise Movement Techniques
- Physical Therapy Modalities
- Breathing Exercises
- Tai Ji
- Qigong
Other Study ID Numbers
- UBAS/ERB/26/4/039
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
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