- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07719010
Feasibility of Velocity Loss-Based Volume Prescription During Constant-Load and Chain-Based Smith Machine Back Squats
July 18, 2026 updated by: Zongwei Chen, South China Normal University
The goal of this observational study was to evaluate the feasibility of percentage of velocity loss (%VL)-based approaches for prescribing training volume during constant-load and chain-based Smith machine back squats.
The study aimed to answer whether %VL can be expressed as the maximum number of repetitions (%Rep) in constant-load and chain-based Smith machine squats.
Twenty-six resistance-trained men performed repetitions-to-failure tests under variable (VRT) and constant resistance training (CRT).
The %Rep attained before reaching different levels of effort were compared between VRT and CRT across various loads and sessions.
Furthermore, this study evaluated the influence of different factors on the predictive accuracy of the %Rep-%VL relationships.
These findings will provide evidence-based evidence in prescribing and monitoring intra-set volume.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
The goal of this observational study was to evaluate the feasibility of percentage of velocity loss (%VL)-based approaches for prescribing training volume during constant-load and chain-based Smith machine back squats.
The study aimed to answer whether %VL can be expressed as the maximum number of repetitions (%Rep) in constant-load and chain-based Smith machine squats.
Twenty-six resistance-trained men performed repetitions-to-failure tests at 85%, 75%, and 65% of their constant-load one-repetition maximum (1RM) under variable (VRT; 40% of the total external load provided by chains) and constant resistance training (CRT; 0% chains).
The %Rep attained before reaching low (10% VL), moderate (20% VL), and high (30% VL) levels of effort were compared between VRT and CRT across various loads and sessions.
Furthermore, this study evaluated the influence of regression type (individual vs. general), load specificity (load-specific vs. multiple-load), and loading configuration (CRT vs. VRT) on the predictive accuracy of the %Rep-%VL relationships established in session 1 for estimating %Rep in session 2. These findings will provide evidence-based evidence in prescribing and monitoring intra-set volume.
Study Type
Observational
Enrollment (Actual)
26
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Guangdong
-
Guangzhou, Guangdong, China, 510006
- School of Physical Education and Sports Science, South China normal university
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
Participant characteristics (mean ± standard deviation [range]) included: age, 20.4 ± 2.1 (18-25) years; body height, 1.78 ± 0.05 (1.68-1.87)
m; body mass, 71.7 ± 7.5 (60.0-91.4)
kg; training experience, 3.5 ± 1.8 (1-10) years; and constant-load 1RM, 135.4 ± 17.4 (95-163) kg, corresponding to 1.89 ± 0.21 (1.58-2.28)
times body mass.
Description
Inclusion Criteria:
- at least 1 year of resistance training experience, performing back squats at least once per week.
- proficiency in the Smith machine back squat executed at maximal intended velocity.
- a constant-load 1RM of ≥ 1.5 times their body mass.
- no reported musculoskeletal injuries in the past three months.
Exclusion Criteria:
- Voluntary withdrawal or injury.
- Not satisfied with inclusion label.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
The %Rep attained before reaching the 10%, 20%, and 30% VL thresholds
Time Frame: April 1st, 2026
|
The %Rep attained before reaching the 10%, 20%, and 30% VL thresholds was recorded across all loads, sessions, and loading configurations.
|
April 1st, 2026
|
|
The %rep predictive accuracy
Time Frame: April 1st, 2026
|
To assess predictive accuracy, second-order polynomial regression equations were generated from the first session of each loading configuration using all repetitions within a set, setting %Rep as the dependent variable and %VL as the independent variable.
These equations were constructed using different regression types (individual vs. general), load specificities (load-specific vs. multiple-load), and loading configurations (CRT vs. VRT).
During the second session, the actual %VL recorded after reaching the 10%, 20%, and 30% VL thresholds was substituted into the corresponding first-session equations to derive the predicted %Rep.
Then, the absolute estimation error was calculated as (|actual %Rep - predicted %Rep|).
In cases where muscular failure occurred before a specific %VL threshold was reached (e.g., 30% VL), the %VL of the final completed repetition was recorded, and the corresponding actual %Rep was defined as 100%.
|
April 1st, 2026
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
October 7, 2025
Primary Completion (Actual)
January 10, 2026
Study Completion (Actual)
May 1, 2026
Study Registration Dates
First Submitted
July 15, 2026
First Submitted That Met QC Criteria
July 18, 2026
First Posted (Actual)
July 22, 2026
Study Record Updates
Last Update Posted (Actual)
July 22, 2026
Last Update Submitted That Met QC Criteria
July 18, 2026
Last Verified
July 1, 2026
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- SCNU-SPT-2025-055
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
The data that support the findings of this study are available from the corresponding author upon reasonable request.
IPD Sharing Time Frame
Individual participant data and supporting documents will become available after publication of the study results and will remain available for 5 years.
IPD Sharing Access Criteria
Individual participant data (IPD) will be shared in anonymized form with qualified researchers for scientific purposes.
The shared data will include lifting velocity of each repetition completed.
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
- SAP
- CSR
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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