Pattern of AFP in Chhidren Admitted at Sohag University Hospital (AFP-SUH)

August 15, 2026 updated by: Mohamed Aboelhamd Ali

Spectrum of Acute Flaccid Paralysis in Children Admitted at Sohag University Hospital

This study is observational study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children at Sohag University Hospital.

Our study will include all children admitted to pediatric emergency and intensive care units with claim or suspicion to have acute falccid paralysis

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

This study is a single center, Observational Cross Sectional Hospital Based study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children aged from birth to 18 years old at Sohag University Hospital.

All included children with acute flaccid paralysis will be subjected to:

All routine investigation (complete blood count, C.R.P, blood gases, serum electrolytes, coagulation profile, liver and kidney function test) Imaging when indicated (Brain C.T, Brain and spine MRI, Nerve Conduction Study)

Study Type

Observational

Enrollment (Estimated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
    • Sohag Governorate
      • Sohag, Sohag Governorate, Egypt, 82511
        • Sohag university hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Pediatric patients aged from 1 month to 16 years old with acute muscle weakness admitted at Sohag University Hospital, Egypt

Description

Inclusion Criteria:

  • All patients admitted to pediatric emergency and intensive care units with claim or suspected to have acute flaccid paralysis aged from 1 month Up to 16 years old

Exclusion Criteria:

  • Children with flaccid paralysis due to causes other than neurogenic causes. No clear history or clinical picture of definite neurological cause. incomplete clinical data.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
AFP Patients
Cjildren from birth to 18 years old with acute muscle weakness who are followed at sohag university hospital
Other: Observitional follow-up
No expiremental intervention. Data will be collected from routine cinical care, medical records and folow up visits according to standard hospital protocols

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Full recovery
Time Frame: 1 Year
Full restoration of muscle strength and function.
1 Year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Partial Recovery with Residual Weakness
Time Frame: 1 Year
Persistent muscle weakness despite improvement
1 Year
Permanent Paralysis
Time Frame: 1 Year
Irreversible loss of motor function due to destruction of motor neurons or severe nerve injury
1 Year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mohamed Aboelhamd Ali

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

September 1, 2027

Study Registration Dates

First Submitted

August 15, 2026

First Submitted That Met QC Criteria

August 15, 2026

First Posted (Actual)

August 20, 2026

Study Record Updates

Last Update Posted (Actual)

August 20, 2026

Last Update Submitted That Met QC Criteria

August 15, 2026

Last Verified

August 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-26-7-33MS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Individual Participants data will not be shared due to patient privacy and data protection policies at Sohag University Hospital

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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