Evaluation of Functional Disability in Rheumatoid Arthritis Patients

August 30, 2026 updated by: Rania Abodaif Mohamed, Sohag University

Functional Disability in Rheumatoid Arthritis and Its Relation to Disease Activity and Radiographic Damage

Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues. Accurate monitoring of disease activity is a cornerstone of the treat-to-target approach in Rheumatoid arthritis.

Study Overview

Status

Not yet recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

150

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

This study will include 100 established Rheumatoid arthritis (RA) patients according the 2010 ACR/EULAR classification criteria for RA, who will be recruited from Rheumatology and Rehabilitation department at Sohag university hospital, in addition to 50 controls will be matched for sex, age, and level of schooling

Description

Inclusion Criteria:

  • • Patients fulfill the 2010 ACR/EULAR classification criteria of Rheumatoid arthritis is based on the confirmed presence of synovitis in at least one joint, absence of an alternative diagnosis better explaining the synovitis, and achievement of a total score of 6 or greater (of a possible 10) from the individual scores in four domains :

    1. number and site of involved joints (range 0-5)
    2. serological abnormality (range 0-3)
    3. elevated acute-phase response (range 0-1)

    4. symptom duration (two levels; range 0-1).

      • Age above 18 years old.
      • Patient cooperative and can answer questions

Exclusion Criteria:

  • • Other rheumatologic or collagen diseases.

    • Age below 18 years and above 65 years.
    • Uncooperative patients.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
rheumatoid arthritis established patients
control group of non rheumatoid patients

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
To evaluate the performance of Rheumatoid Arthritis Impact of Disease (RAID) questionnaire in detecting disease flares in Rheumatoid arthritis patients and to compare it with other disease activity indices.
Time Frame: 1 year
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 20, 2026

Primary Completion (Estimated)

January 20, 2027

Study Completion (Estimated)

August 20, 2027

Study Registration Dates

First Submitted

August 30, 2026

First Submitted That Met QC Criteria

August 30, 2026

First Posted (Actual)

September 3, 2026

Study Record Updates

Last Update Posted (Actual)

September 3, 2026

Last Update Submitted That Met QC Criteria

August 30, 2026

Last Verified

July 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-26-7-25MS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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