Effectiveness of Integrated Multimodal Digital and Specimen-Based Neuroanatomy Teaching Among Medical Students

September 24, 2026 updated by: Khin Ei Ei Saw

Effectiveness of Integrated Multimodal Digital and Specimen-Based Neuroanatomy Teaching in Improving Knowledge, Reducing Perceived Learning Difficulty, and Enhancing Confidence Among Medical Students

This three-phase randomized controlled educational intervention trial will evaluate the effectiveness of integrated multimodal digital and specimen-based neuroanatomy teaching compared with traditional specimen-based revision among Medical Year 2 students. The study will assess knowledge, perceived learning difficulty, and confidence in a difficult neuroanatomy topic identified through a baseline assessment.

Study Overview

Detailed Description

The study will be conducted in three phases. In Phase 1, students will receive traditional neuroanatomy teaching followed by a 50-item single-best-answer assessment, topic difficulty ratings, and confidence ratings to identify the most challenging neuroanatomy topic.

In Phase 2, students will be randomly allocated after stratification based on previous module academic performance. Group A will receive an integrated multimodal digital and specimen-based neuroanatomy teaching session, while Group B will receive a traditional specimen-based revision session as a wait-list control. Both groups will receive a 90-minute structured teaching session covering identical learning objectives.

In Phase 3, students will complete an immediate post-intervention 20-item single-best-answer assessment and confidence questionnaire. Group B will subsequently receive the integrated multimodal digital and specimen-based teaching intervention.

Study Type

Interventional

Enrollment (Estimated)

114

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

    • Shan State
      • Taunggyi, Shan State, Burma, 06017
        • University of Medicine, Taunggyi
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Medical Year 2 students enrolled in the Neurology and Mental Health Module.
  • Students who provide informed consent.

Exclusion Criteria:

  • Students absent during intervention sessions.
  • Students who do not complete both pre- and post-tests.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Integrated Multimodal Digital and Specimen-Based Teaching

A 90-minute structured integrated multimodal digital and specimen-based neuroanatomy teaching session using virtual dissection, three-dimensional digital visualization, pathway animations/drawing/mapping, sectional CT/MRI imaging, physical 3D models, specimen-based learning, interactive learning activities, and clinical case integration.

Participants assigned to the intervention group will receive integrated multimodal neuroanatomy teaching using multiple complementary learning modalities. The intervention will incorporate 3D virtual dissection and anatomical segmentation using the Asclepius virtual dissection table, physical anatomical specimens and three-dimensional models, pathway animation and instructor-guided drawing/mapping, two-dimensional CT/MRI brain cross-sectional images, and case-based learning (CBL). These modalities will be integrated around the selected difficult neuroanatomy topic to facilitate three-dimensional spatial understanding, anatomical relationships, pathway organization, and clinical application.

The intervention will be delivered by the same instructor using a standardized teaching session. Participants in the wait-list control group will receive the integrated multimodal neuroanatomy teaching after completion of the post-intervention assessment.

Active Comparator: Traditional Specimen-Based Revision

A 90-minute structured traditional specimen-based revision session consisting of a brief review lecture and demonstration of formalin-fixed anatomical specimens, following standardized learning objectives and teaching materials.

Participants assigned to the active comparator group will receive traditional specimen-based neuroanatomy revision using formalin-fixed anatomical specimens and instructor-guided review of relevant anatomical structures and relationships. The session will follow the conventional specimen-based teaching approach used for neuroanatomy revision.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Post-intervention knowledge score
Time Frame: Immediately after the intervention session

Score on the 20-item Single-Best-Answer Assessment of the selected difficult neuroanatomy topic, ranging from 0 to 20, with higher scores indicating better knowledge.

Immediately after the intervention session

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Confidence level
Time Frame: Immediately after the intervention session

Participants' confidence in learning the selected difficult neuroanatomy topic, assessed using a 5-point Likert scale ranging from 1 to 5, with higher scores indicating greater confidence.

Immediately after the intervention session
Perceived learning difficulty
Time Frame: Immediately after the intervention session

Participants' perceived difficulty of the selected neuroanatomy topic, assessed using a 5-point Likert scale ranging from 1 to 5, with higher scores indicating greater perceived difficulty.

Immediately after the intervention session

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

September 29, 2026

Primary Completion (Estimated)

October 2, 2026

Study Completion (Estimated)

October 2, 2026

Study Registration Dates

First Submitted

September 19, 2026

First Submitted That Met QC Criteria

September 19, 2026

First Posted (Actual)

September 25, 2026

Study Record Updates

Last Update Posted (Actual)

September 29, 2026

Last Update Submitted That Met QC Criteria

September 24, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • 3-IR-ERC-UMTGI-1-2026

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Individual participant data will not be shared because the study involves individual-level educational data from medical students. Although the data will be de-identified for analysis, access to the participant-level dataset will be restricted to the research team to protect participant privacy and confidentiality.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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