BioMIND Biospecimen Repository (BBR)

October 29, 2026 updated by: Jaspreet Bhangu, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

BioMIND Repository for the Collection and Storage of Biospecimens From Individuals With Memory Concerns

The purpose of the BBR is to facilitate scientific research by serving as a local and external resource for the distribution of human blood and CSF biospecimens, together with their corresponding clinical data, to internal and external researchers.

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Other: blood sample and optional csf collection

Detailed Description

The goals for establishing the BBR are to:

Establish the BBR at Parkwood Institute for the storage and archiving of human blood and CSF.
Establish a local oversight committee composed of neurologists and community representatives to manage operations, review sample requests, and facilitate local, national, and external collaboration.
Distribute well-characterized, high-quality biospecimens to internal and external scientific researchers.
Promote public awareness of the importance of biospecimen collection in supporting brain disease research.

Study Type

Observational

Enrollment (Estimated)

1000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Canada
- Ontario
  - London, Ontario, Canada, N6C0A7
    - Parkwood Institute

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Eligible patients from the Aging Brain and Memory Clinic (ABMC), Cognitive Neurology, or participants who are enrolled in other research projects affiliated with the Cognitive Clinical Research Group or Cognitive Neurology will be invited to participate in the biorepository. This targeted recruitment strategy ensures that participants have relevant clinical profiles, facilitating efficient enrollment and supporting the study's focus on neurodegenerative conditions.

Description

Inclusion Criteria:

Written informed consent obtained and documented, either from the participant or the substitute decision-maker.
Must be a patient from the Aging Brain and Memory Clinic, Cognitive Neurology, or enrolled in other research projects affiliated with the Cognitive Clinical Research Group or Cognitive Neurology.
Geographic accessibility to the collection site.
Ability to read, speak, and understand English.

Exclusion Criteria:

Age under 18 years (pediatric population)
Infectious disease cases such as prion diseases (e.g. Creutzfeldt-Jakob Disease), Human Immunodeficiency Virus, Ebola, or any other pathogen requiring containment above Biosafety Level 1.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Observational Models: OTHER
Time Perspectives: PROSPECTIVE

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
facilitate scientific research Time Frame: 5 years	The purpose of the BBR is to advance neurodegenerative disease research by providing high-quality human blood and cerebrospinal fluid (CSF) biospecimens, together with linked clinical, cognitive, imaging, and biomarker data, to internal and external investigators. Successful outcomes will be measured by the utilization of these resources to support biomarker discovery, validation, and implementation studies aimed at improving the diagnosis, prognosis, monitoring, and treatment of neurodegenerative disorders.	5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

November 1, 2026

Primary Completion (Estimated)

December 1, 2030

Study Completion (Estimated)

December 1, 2030

Study Registration Dates

First Submitted

October 22, 2026

First Submitted That Met QC Criteria

October 29, 2026

First Posted (Actual)

November 3, 2026

Study Record Updates

Last Update Posted (Actual)