- ICH GCP
- Registr klinických studií v USA
- Klinická studie NCT05311202
The Effect of Acute Resistance Exercise on Inhibitory Control
9. května 2022 aktualizováno: Yu-Kai Chang, National Taiwan Normal University
The Effect of Training Volume and Intensity of Acute Resistance Exercise on Inhibitory Control: An Event-Related Potential Study
The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.
Přehled studie
Postavení
Nábor
Podmínky
Detailní popis
The current study is expected that 175 healthy adults will be recruited and randomly assigned to control group, low volume-moderate intensity, moderate volume-moderate intensity, high volume-moderate intensity, or moderate volume-low intensity group, with 35 participants in each group.
Participants will be required to conduct two experiments.
The first was the familiarity experiment, which consisted of the experiment description, the familiarity test, and the 6 Repetition Maximum (RM) test.
The process lasted about 3 hours.
The exercise group was given a warm-up exercise before the intervention, followed by resistance exercise, including Bench Press, Rowing, Deadlift, and Squat, all completed on the Smith machine.
After the exercise, the group was given a cool down, while the control group was given 30 minutes of reading.
Before and after the intervention, Stroop, event-related potential and fingertip blood lactate were measured, and another fingertip blood lactate was measured 10 minutes after the intervention, which lasted about 3 hours.
Typ studie
Intervenční
Zápis (Očekávaný)
175
Fáze
- Nelze použít
Kontakty a umístění
Tato část poskytuje kontaktní údaje pro ty, kteří studii provádějí, a informace o tom, kde se tato studie provádí.
Studijní místa
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-
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Taipei, Tchaj-wan, 106
- Nábor
- National Taiwan Normal University
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Kontakt:
- Yan-Ho Lo, Master
- Telefonní číslo: 0903679058
- E-mail: yanholo@hotmail.com
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Vrchní vyšetřovatel:
- Yan-Ho Lo, Master
-
-
Kritéria účasti
Výzkumníci hledají lidi, kteří odpovídají určitému popisu, kterému se říká kritéria způsobilosti. Některé příklady těchto kritérií jsou celkový zdravotní stav osoby nebo předchozí léčba.
Kritéria způsobilosti
Věk způsobilý ke studiu
20 let až 26 let (Dospělý)
Přijímá zdravé dobrovolníky
Ano
Pohlaví způsobilá ke studiu
Všechno
Popis
Inclusion Criteria:
- The dominant hand is right-handed
- 18.5 < BMI < 26
- Can cooperate with fingertip blood collection
- No color blindness and epilepsy
- Not taking medications that affect brain function
- Irregular exercise (more than 150 minutes per week for 3 months)
Exclusion Criteria:
- The participants who do not meet the inclusion or The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) Criteria.
Studijní plán
Tato část poskytuje podrobnosti o studijním plánu, včetně toho, jak je studie navržena a co studie měří.
Jak je studie koncipována?
Detaily designu
- Primární účel: Výzkum zdravotnických služeb
- Přidělení: Randomizované
- Intervenční model: Paralelní přiřazení
- Maskování: Žádné (otevřený štítek)
Zbraně a zásahy
Skupina účastníků / Arm |
Intervence / Léčba |
|---|---|
|
Experimentální: low-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 30 minutes
|
The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 20 minutes of two sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
|
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Experimentální: moderate-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 40 minutes
|
The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 30 minutes of three sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
|
|
Experimentální: high-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 50 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 40 minutes of four sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
|
|
Experimentální: moderate-volume low-intensity group
Participants will attend the trainer-supervised resistance exercise program for 45 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 35 minutes of four sets of low intensity resistance exercise with 20 repetitions; (3) 5 minutes of cool down
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Experimentální: Control group
Reading for 40 minutes
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Reading a book related to cognitive function & exercise for 40 minutes
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Co je měření studie?
Primární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
|
Changes In Inhibitory Control
Časové okno: 30 minutes each before & after intervention
|
The computerized Stroop test will be administrated to assess participants' inhibitory function, and the changes in Emotional Stroop test performance (i.e., response time and accuracy) before (pre-test) and after (post-test) intervention will be examined.
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30 minutes each before & after intervention
|
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Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis
Časové okno: 30 minutes each before & after intervention
|
The continuous electroencephalogram (EEG) activity of each participant will be recorded throughout the entire Stroop task using a Neuroscan Quick-Cap, with 32 Ag/AgCl electrodes arranged following the international 10-20 system (NeuroScan Inc., El Paso, TX, USA).
Changes in the neuroelectrical activities before and after the intervention will be examined.
The time windows for each ERP component will be determined based on a visual inspection of the averaged grand waveform.
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30 minutes each before & after intervention
|
Sekundární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
|
Changes In Positive & Negative Affect
Časové okno: 5 minutes after pre-test and post-test of Stroop test
|
The changes in the Positive & Negative affect after pre-and post-test will be assessed by The Positive and Negative Affect Schedule (PANAS) questionnaire, which is made up of two 10-item scales that assess both positive and negative emotions.
Each item is scored on a scale of 1 (not at all) to 5 (very much).
|
5 minutes after pre-test and post-test of Stroop test
|
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Muscular Fitness Measurements (1RM)-Deadlift
Časové okno: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 10-20% for lower body exercises.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
The 1RM will be caculated by the results of 6-RM protocol.
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2 hours on the first day
|
|
Muscular Fitness Measurements (1RM)-Bench Press
Časové okno: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 5-10%.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
|
2 hours on the first day
|
|
Muscular Fitness Measurements (1RM)-Squat
Časové okno: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 10-20% for.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
|
2 hours on the first day
|
|
Muscular Fitness Measurements (1RM)-Rowing
Časové okno: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 5-10%.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
|
2 hours on the first day
|
|
Changes In Concentration Of Blood Lactate
Časové okno: 2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test)
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Fingertip Blood samples will be collected using Lactate Analyzer in three times point: before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test, and analysed the change in concentration of blood lactate between the three time points.
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2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test)
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Spolupracovníci a vyšetřovatelé
Zde najdete lidi a organizace zapojené do této studie.
Vyšetřovatelé
- Vrchní vyšetřovatel: Yu-Kai Chang, Ph.D., Department of Physical Education and Sport Sciences, National Taiwan Normal University
Termíny studijních záznamů
Tato data sledují průběh záznamů studie a předkládání souhrnných výsledků na ClinicalTrials.gov. Záznamy ze studií a hlášené výsledky jsou před zveřejněním na veřejné webové stránce přezkoumány Národní lékařskou knihovnou (NLM), aby se ujistily, že splňují specifické standardy kontroly kvality.
Hlavní termíny studia
Začátek studia (Aktuální)
1. dubna 2022
Primární dokončení (Očekávaný)
30. září 2022
Dokončení studie (Očekávaný)
31. prosince 2022
Termíny zápisu do studia
První předloženo
16. března 2022
První předloženo, které splnilo kritéria kontroly kvality
27. března 2022
První zveřejněno (Aktuální)
5. dubna 2022
Aktualizace studijních záznamů
Poslední zveřejněná aktualizace (Aktuální)
13. května 2022
Odeslaná poslední aktualizace, která splnila kritéria kontroly kvality
9. května 2022
Naposledy ověřeno
1. května 2022
Více informací
Termíny související s touto studií
Klíčová slova
Další identifikační čísla studie
- PACNL_202201HM012
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