- ICH GCP
- Registro degli studi clinici negli Stati Uniti
- Sperimentazione clinica NCT05311202
The Effect of Acute Resistance Exercise on Inhibitory Control
9 maggio 2022 aggiornato da: Yu-Kai Chang, National Taiwan Normal University
The Effect of Training Volume and Intensity of Acute Resistance Exercise on Inhibitory Control: An Event-Related Potential Study
The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.
Panoramica dello studio
Stato
Reclutamento
Condizioni
Descrizione dettagliata
The current study is expected that 175 healthy adults will be recruited and randomly assigned to control group, low volume-moderate intensity, moderate volume-moderate intensity, high volume-moderate intensity, or moderate volume-low intensity group, with 35 participants in each group.
Participants will be required to conduct two experiments.
The first was the familiarity experiment, which consisted of the experiment description, the familiarity test, and the 6 Repetition Maximum (RM) test.
The process lasted about 3 hours.
The exercise group was given a warm-up exercise before the intervention, followed by resistance exercise, including Bench Press, Rowing, Deadlift, and Squat, all completed on the Smith machine.
After the exercise, the group was given a cool down, while the control group was given 30 minutes of reading.
Before and after the intervention, Stroop, event-related potential and fingertip blood lactate were measured, and another fingertip blood lactate was measured 10 minutes after the intervention, which lasted about 3 hours.
Tipo di studio
Interventistico
Iscrizione (Anticipato)
175
Fase
- Non applicabile
Contatti e Sedi
Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.
Luoghi di studio
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Taipei, Taiwan, 106
- Reclutamento
- National Taiwan Normal University
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Contatto:
- Yan-Ho Lo, Master
- Numero di telefono: 0903679058
- Email: yanholo@hotmail.com
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Investigatore principale:
- Yan-Ho Lo, Master
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Criteri di partecipazione
I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.
Criteri di ammissibilità
Età idonea allo studio
Da 20 anni a 26 anni (Adulto)
Accetta volontari sani
Sì
Sessi ammissibili allo studio
Tutto
Descrizione
Inclusion Criteria:
- The dominant hand is right-handed
- 18.5 < BMI < 26
- Can cooperate with fingertip blood collection
- No color blindness and epilepsy
- Not taking medications that affect brain function
- Irregular exercise (more than 150 minutes per week for 3 months)
Exclusion Criteria:
- The participants who do not meet the inclusion or The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) Criteria.
Piano di studio
Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.
Come è strutturato lo studio?
Dettagli di progettazione
- Scopo principale: Ricerca sui servizi sanitari
- Assegnazione: Randomizzato
- Modello interventistico: Assegnazione parallela
- Mascheramento: Nessuno (etichetta aperta)
Armi e interventi
Gruppo di partecipanti / Arm |
Intervento / Trattamento |
|---|---|
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Sperimentale: low-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 30 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 20 minutes of two sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
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Sperimentale: moderate-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 40 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 30 minutes of three sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
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Sperimentale: high-volume moderate-intensity group
Participants will attend the trainer-supervised resistance exercise program for 50 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 40 minutes of four sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down
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Sperimentale: moderate-volume low-intensity group
Participants will attend the trainer-supervised resistance exercise program for 45 minutes
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The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 35 minutes of four sets of low intensity resistance exercise with 20 repetitions; (3) 5 minutes of cool down
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Sperimentale: Control group
Reading for 40 minutes
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Reading a book related to cognitive function & exercise for 40 minutes
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Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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Changes In Inhibitory Control
Lasso di tempo: 30 minutes each before & after intervention
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The computerized Stroop test will be administrated to assess participants' inhibitory function, and the changes in Emotional Stroop test performance (i.e., response time and accuracy) before (pre-test) and after (post-test) intervention will be examined.
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30 minutes each before & after intervention
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Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis
Lasso di tempo: 30 minutes each before & after intervention
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The continuous electroencephalogram (EEG) activity of each participant will be recorded throughout the entire Stroop task using a Neuroscan Quick-Cap, with 32 Ag/AgCl electrodes arranged following the international 10-20 system (NeuroScan Inc., El Paso, TX, USA).
Changes in the neuroelectrical activities before and after the intervention will be examined.
The time windows for each ERP component will be determined based on a visual inspection of the averaged grand waveform.
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30 minutes each before & after intervention
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Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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Changes In Positive & Negative Affect
Lasso di tempo: 5 minutes after pre-test and post-test of Stroop test
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The changes in the Positive & Negative affect after pre-and post-test will be assessed by The Positive and Negative Affect Schedule (PANAS) questionnaire, which is made up of two 10-item scales that assess both positive and negative emotions.
Each item is scored on a scale of 1 (not at all) to 5 (very much).
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5 minutes after pre-test and post-test of Stroop test
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Muscular Fitness Measurements (1RM)-Deadlift
Lasso di tempo: 2 hours on the first day
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The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 10-20% for lower body exercises.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
The 1RM will be caculated by the results of 6-RM protocol.
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2 hours on the first day
|
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Muscular Fitness Measurements (1RM)-Bench Press
Lasso di tempo: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 5-10%.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
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2 hours on the first day
|
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Muscular Fitness Measurements (1RM)-Squat
Lasso di tempo: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 10-20% for.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
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2 hours on the first day
|
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Muscular Fitness Measurements (1RM)-Rowing
Lasso di tempo: 2 hours on the first day
|
The greatest weight an individual is capable of lifting for one repetition (1RM) will be examined using the 6-RM assessment according to the American College of Sports Medicine (ACSM) protocol.
There were multiple steps in the resistance exercise assessment process.
Warming up at a low intensity for 1 minute will be followed by a 1-minute rest break.
For the first set of exercises, each person's workload (lbs) will be increased by 5-10%.
Participants will be told to do 10 repetitions followed by a 2-minute rest break during this step.
Following that, a steadily increasing load will be applied until the load can only be completed less than 6 repetitions.
The numbers of set will be limited to the minimum 1set to maximum 4sets.
1RM will be caculated by the results of 6-RM protocol.
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2 hours on the first day
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Changes In Concentration Of Blood Lactate
Lasso di tempo: 2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test)
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Fingertip Blood samples will be collected using Lactate Analyzer in three times point: before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test, and analysed the change in concentration of blood lactate between the three time points.
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2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test)
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Collaboratori e investigatori
Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.
Investigatori
- Investigatore principale: Yu-Kai Chang, Ph.D., Department of Physical Education and Sport Sciences, National Taiwan Normal University
Studiare le date dei record
Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.
Studia le date principali
Inizio studio (Effettivo)
1 aprile 2022
Completamento primario (Anticipato)
30 settembre 2022
Completamento dello studio (Anticipato)
31 dicembre 2022
Date di iscrizione allo studio
Primo inviato
16 marzo 2022
Primo inviato che soddisfa i criteri di controllo qualità
27 marzo 2022
Primo Inserito (Effettivo)
5 aprile 2022
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
13 maggio 2022
Ultimo aggiornamento inviato che soddisfa i criteri QC
9 maggio 2022
Ultimo verificato
1 maggio 2022
Maggiori informazioni
Termini relativi a questo studio
Parole chiave
Altri numeri di identificazione dello studio
- PACNL_202201HM012
Piano per i dati dei singoli partecipanti (IPD)
Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?
NO
Informazioni su farmaci e dispositivi, documenti di studio
Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti
No
Studia un dispositivo regolamentato dalla FDA degli Stati Uniti
No
Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .
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