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Kemoterapi Plus strålebehandling til behandling af patienter med trin II eller trin III anal cancer

30. december 2016 opdateret af: Radiation Therapy Oncology Group

En fase III randomiseret undersøgelse af 5-Fluorouracil, Mitomycin-C og strålebehandling versus 5-fluorouracil, cisplatin og strålebehandling ved karcinom i analkanalen

RATIONALE: Lægemidler, der bruges i kemoterapi, bruger forskellige måder til at forhindre tumorceller i at dele sig, så de holder op med at vokse eller dør. Kombination af mere end ét lægemiddel eller kombination af strålebehandling med kemoterapi kan dræbe flere tumorceller. Det vides endnu ikke, om fluorouracil og mitomycin plus strålebehandling er mere effektiv end fluorouracil og cisplatin plus strålebehandling til analkræft.

FORMÅL: Dette randomiserede fase III forsøg studerer fluorouracil og mitomycin plus strålebehandling for at se, hvor godt det virker sammenlignet med fluorouracil og cisplatin plus strålebehandling til behandling af patienter med stadium II eller stadium III anal cancer.

Studieoversigt

Status

Afsluttet

Betingelser

Anal kræft

Intervention / Behandling

Detaljeret beskrivelse

MÅL:

Sammenlign de initiale og totale lokal- og fjernsvigtfrekvenser hos patienter med analkanalcancer behandlet med enten fluorouracil (5-FU) plus mitomycin samtidig med strålebehandling eller 5-FU plus cisplatin efterfulgt af 5-FU plus cisplatin samtidig med strålebehandling.
Identificer eventuelle forskelle i lokal kontrol og kolostomifrekvenser efter 2 år hos patienter behandlet med disse regimer.
Bestem enhver forskel i kolostomifri, sygdomsfri eller samlet overlevelse hos patienter behandlet med disse regimer.
Sammenlign de toksiske virkninger af disse kure hos disse patienter.
Evaluer de prognostiske virkninger af tumormarkører P53-overekspression, human papillomavirusstatus og enzym HAP1 hos patienter behandlet med disse regimer.

OVERSIGT: Dette er en randomiseret undersøgelse. Patienterne stratificeres efter køn, nodalstatus (positiv vs negativ) og primær tumorstørrelse (større end 2 cm til 5 cm vs. større end 5 cm). Patienterne randomiseres til 1 ud af 2 behandlingsarme.

Arm I: Patienterne får fluorouracil (5-FU) IV kontinuerligt over 96 timer begyndende på dag 1 og 29 og mitomycin IV på dag 1 og 29 med samtidig strålebehandling.
Arm II: Patienter modtager induktionskemoterapi omfattende 5-FU IV kontinuerligt over 96 timer begyndende på dag 1, 29, 57 og 85 og cisplatin IV over 1 time på dag 1, 29, 57 og 85. Fra dag 57 modtager patienter samtidig strålebehandling.

I begge arme administreres strålebehandling dagligt, 5 dage om ugen, i 5-6,5 uger. Patienter med T3, T4 eller N+ læsioner eller T2 læsioner med resterende sygdom modtager yderligere strålebehandling til et reduceret felt.

Patienterne følges hver 3. måned i 1 år, hver 6. måned i 1 år og derefter årligt.

PROJEKTERET TILSLUTNING: I alt 650 patienter vil blive akkumuleret til denne undersøgelse inden for 5 år.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

682

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Forenede Stater
- Alabama
  - Birmingham, Alabama, Forenede Stater, 35294
    - Comprehensive Cancer Center at University of Alabama at Birmingham
  - Mobile, Alabama, Forenede Stater, 36607
    - Mobile Infirmary Medical Center
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Regional Hospital
- Arizona
  - Phoenix, Arizona, Forenede Stater, 85013
    - Foundation for Cancer Research and Education
  - Scottsdale, Arizona, Forenede Stater, 85259
    - CCOP - Mayo Clinic Scottsdale Oncology Program
- Arkansas
  - Ft. Smith, Arkansas, Forenede Stater, 72903
    - Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
- California
  - Berkeley, California, Forenede Stater, 94705
    - Alta Bates Comprehensive Cancer Center
  - Burbank, California, Forenede Stater, 91505
    - Providence Saint Joseph Medical Center - Burbank
  - Burlingame, California, Forenede Stater, 94010
    - Mills-Peninsula Health Services
  - Concord, California, Forenede Stater, 94520
    - Mount Diablo Regional Cancer Center
  - Duarte, California, Forenede Stater, 91010
    - City of Hope Comprehensive Cancer Center
  - Fresno, California, Forenede Stater, 93720
    - California Cancer Center - Woodward Park Office
  - Greenbrae, California, Forenede Stater, 94904
    - Sutter Health Western Division Cancer Research Group
  - Greenbrae, California, Forenede Stater, 94904
    - Marin Cancer Institute at Marin General Hospital
  - Hayward, California, Forenede Stater, 94545
    - Saint Rose Hospital
  - Livermore, California, Forenede Stater, 94550
    - Valley Memorial Hospital
  - Loma Linda, California, Forenede Stater, 92354
    - Loma Linda University Cancer Institute at Loma Linda University Medical Center
  - Los Angeles, California, Forenede Stater, 90033-0804
    - USC/Norris Comprehensive Cancer Center and Hospital
  - Mission Hills, California, Forenede Stater, 91346-9600
    - Providence Holy Cross Cancer Center
  - Modesto, California, Forenede Stater, 95355
    - Memorial Medical Center Cancer Services
  - Northridge, California, Forenede Stater, 91325
    - Leavey Cancer Center at Northridge Hospital Medical Center
  - Oakland, California, Forenede Stater, 94602
    - Highland General Hospital
  - Oakland, California, Forenede Stater, 94609
    - CCOP - Bay Area Tumor Institute
  - Oakland, California, Forenede Stater, 94609
    - Summit Medical Center
  - Palo Alto, California, Forenede Stater, 94301
    - Palo Alto Medical Foundation
  - Pomona, California, Forenede Stater, 91767
    - Pomona Valley Hospital Medical Center
  - Sacramento, California, Forenede Stater, 95817
    - University of California Davis Cancer Center
  - Sacramento, California, Forenede Stater, 95815
    - Radiological Associates of Sacramento Medical Group, Inc.
  - San Diego, California, Forenede Stater, 92134
    - Naval Medical Center - San Diego
  - San Francisco, California, Forenede Stater, 94118
    - California Pacific Medical Center - California Campus
  - San Pablo, California, Forenede Stater, 94806
    - J.C. Robinson, M.D. Regional Cancer Center
  - Sana Rosa, California, Forenede Stater, 95405
    - CCOP - Santa Rosa Memorial Hospital
  - Torrance, California, Forenede Stater, 90509
    - Torrance Memorial Medical Center
  - Vallejo, California, Forenede Stater, 94589
    - Sutter Solano Medical Center
- Colorado
  - Aurora, Colorado, Forenede Stater, 80012
    - Aurora Presbyterian Hospital
  - Boulder, Colorado, Forenede Stater, 80301
    - Boulder Community Hospital
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Memorial Hospital Cancer Center
  - Colorado Springs, Colorado, Forenede Stater, 80933
    - Penrose Cancer Center at Penrose Hospital
  - Denver, Colorado, Forenede Stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forenede Stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forenede Stater, 80218
    - Presbyterian - St. Luke's Medical Center
  - Denver, Colorado, Forenede Stater, 80218
    - St. Joseph Hospital
  - Denver, Colorado, Forenede Stater, 80224-2522
    - CCOP - Colorado Cancer Research Program, Incorporated
  - Englewood, Colorado, Forenede Stater, 80110
    - Swedish Medical Center
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Front Range Cancer Specialists
  - Grand Junction, Colorado, Forenede Stater, 81502
    - St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
  - Lone Tree, Colorado, Forenede Stater, 80124
    - Sky Ridge Medical Center
  - Longmont, Colorado, Forenede Stater, 80502
    - Hope Cancer Care Center at Longmont United Hospital
  - Pueblo, Colorado, Forenede Stater, 81004
    - St. Mary-Corwin Regional Medical Center
  - Thorton, Colorado, Forenede Stater, 80229
    - North Suburban Medical Center
- Connecticut
  - Middletown, Connecticut, Forenede Stater, 06457
    - Middlesex Hospital Cancer Center
- Delaware
  - Lewes, Delaware, Forenede Stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forenede Stater, 19718
    - CCOP - Christiana Care Health Services
  - Wilmington, Delaware, Forenede Stater, 19805
    - St. Francis Hospital
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20007
    - Lombardi Cancer Center at Georgetown University Medical Center
- Florida
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
  - Fort Myers, Florida, Forenede Stater, 33901
    - 21st Century Oncology - Fort Myers
  - Hollywood, Florida, Forenede Stater, 33021
    - Memorial Cancer Institute at Memorial Regional Hospital
  - Jacksonville, Florida, Forenede Stater, 32207
    - Baptist Cancer Institute - Jacksonville
  - Jacksonville, Florida, Forenede Stater, 32224-9980
    - Mayo Clinic - Jacksonville
  - Jupiter, Florida, Forenede Stater, 33458
    - Ella Milbank Foshay Cancer Center at Jupiter Medical Center
  - Miami, Florida, Forenede Stater, 33136
    - University of Miami Sylvester Comprehensive Cancer Center
  - Miami, Florida, Forenede Stater, 33176
    - Baptist-South Miami Regional Cancer Program
  - Miami Beach, Florida, Forenede Stater, 33140
    - CCOP - Mount Sinai Medical Center
  - Panama City, Florida, Forenede Stater, 32405
    - Gulf Coast Cancer Treatment Center
  - Tallahassee, Florida, Forenede Stater, 32308
    - Tallahassee Memorial Hospital
  - Tampa, Florida, Forenede Stater, 33612
    - H. Lee Moffitt Cancer Center and Research Institute at University of South Florida
- Georgia
  - Altanta, Georgia, Forenede Stater, 30322
    - Emory University Hospital - Atlanta
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast Georgia Medical Center
  - Valdosta, Georgia, Forenede Stater, 31603
    - Pearlman Comprehensive Cancer Center at South Georgia Medical Center
- Idaho
  - Boise, Idaho, Forenede Stater, 83706
    - Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
  - Boise, Idaho, Forenede Stater, 83712
    - Mountain States Tumor Institute - Boise
- Illinois
  - Alton, Illinois, Forenede Stater, 62002
    - Saint Anthony's Hospital at Saint Anthony's Health Center
  - Arlington Heights, Illinois, Forenede Stater, 60005
    - Northwest Community Hospital
  - Aurora, Illinois, Forenede Stater, 60507
    - Rush-Copley Cancer Care Center
  - Barrington, Illinois, Forenede Stater, 60010
    - Good Shepherd Hospital
  - Bloomington, Illinois, Forenede Stater, 61701
    - St. Joseph Medical Center
  - Canton, Illinois, Forenede Stater, 61520
    - Graham Hospital
  - Carthage, Illinois, Forenede Stater, 62321
    - Memorial Hospital
  - Chicago, Illinois, Forenede Stater, 60611
    - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
  - Chicago, Illinois, Forenede Stater, 60657
    - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
  - Downers Grove, Illinois, Forenede Stater, 60515
    - Cancer Care Center at Advocate Good Samaritan Hospital
  - Effingham, Illinois, Forenede Stater, 62401
    - St. Anthony's Memorial Hospital
  - Eureka, Illinois, Forenede Stater, 61530
    - Eureka Hospital
  - Evanston, Illinois, Forenede Stater, 60201
    - Evanston Northwestern Health Care - Evanston Hospital
  - Galesburg, Illinois, Forenede Stater, 61401
    - Galesburg Cottage Hospital
  - Galesburg, Illinois, Forenede Stater, 61401
    - Galesburg Clinic
  - Galesburg, Illinois, Forenede Stater, 61401
    - InterCommunity Cancer Center of Western Illinois
  - Havana, Illinois, Forenede Stater, 62644
    - Mason District Hospital
  - Hinsdale, Illinois, Forenede Stater, 60521
    - Hinsdale Hematology Oncology Associates
  - Hopedale, Illinois, Forenede Stater, 61747
    - Hopedale Medical Complex
  - Joliet, Illinois, Forenede Stater, 60435
    - Joliet Oncology Hematology Associates, Limited - West
  - Kewanee, Illinois, Forenede Stater, 61443
    - Kewanee Hospital
  - Macomb, Illinois, Forenede Stater, 61455
    - Mcdonough District Hospital
  - Naperville, Illinois, Forenede Stater, 60566
    - Edward Hospital Cancer Center
  - Normal, Illinois, Forenede Stater, 61761
    - Bromenn Regional Medical Center
  - Normal, Illinois, Forenede Stater, 61761
    - Community Cancer Center
  - Ottawa, Illinois, Forenede Stater, 61350
    - Community Hospital of Ottawa
  - Ottawa, Illinois, Forenede Stater, 61350
    - Oncology Hematology Associates of Central Illinois - Ottawa
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Lutheran General Cancer Care Center
  - Pekin, Illinois, Forenede Stater, 61554
    - Cancer Treatment Center at Pekin Hospital
  - Peoria, Illinois, Forenede Stater, 61614
    - Proctor Hospital
  - Peoria, Illinois, Forenede Stater, 61603
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forenede Stater, 61637
    - OSF St. Francis Medical Center
  - Peoria, Illinois, Forenede Stater, 61615
    - CCOP - Illinois Oncology Research Association
  - Peoria, Illinois, Forenede Stater, 61615
    - Oncology/Hematology Associates of Central Illinois, P.C.
  - Peru, Illinois, Forenede Stater, 61354
    - Illinois Valley Community Hospital
  - Princeton, Illinois, Forenede Stater, 61356
    - Perry Memorial Hospital
  - Rockford, Illinois, Forenede Stater, 61104
    - Swedish American Hospital
  - Spring Valley, Illinois, Forenede Stater, 61362
    - St. Margaret's Hospital
  - Spring Valley, Illinois, Forenede Stater, 61362
    - Valley Cancer Center
  - Urbana, Illinois, Forenede Stater, 61801
    - Carle Cancer Center at Carle Foundation Hospital
  - Urbana, Illinois, Forenede Stater, 61801
    - CCOP - Carle Cancer Center
- Indiana
  - Beech Grove, Indiana, Forenede Stater, 46107
    - St. Francis Hospital and Health Centers
  - Bloomington, Indiana, Forenede Stater, 47403
    - Bloomington Hospital
  - Elkhart, Indiana, Forenede Stater, 46515
    - Elkhart General Hospital
  - La Porte, Indiana, Forenede Stater, 46350
    - Center for Cancer Therapy at LaPorte Hospital and Health Services
  - Michigan City, Indiana, Forenede Stater, 46360
    - Saint Anthony Memorial Health Centers
  - Muncie, Indiana, Forenede Stater, 47303
    - Cancer Center at Ball Memorial Hospital
  - Plymouth, Indiana, Forenede Stater, 46544
    - Saint Joseph Regional Medical Center - Plymouth Campus
  - South Bend, Indiana, Forenede Stater, 46601
    - Memorial Hospital of South Bend
  - South Bend, Indiana, Forenede Stater, 46601
    - CCOP - Northern Indiana CR Consortium
  - Terre Haute, Indiana, Forenede Stater, 47804
    - Union Hospital
- Iowa
  - Ames, Iowa, Forenede Stater, 50010
    - McFarland Clinic, P.C.
  - Carroll, Iowa, Forenede Stater, 51401
    - Saint Anthony Regional Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52402
    - St. Luke's Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Cedar Rapids Oncology Associates
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Mercy Cancer Center at Mercy Medical Center
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Alegent Health Mercy Hospital
  - Davenport, Iowa, Forenede Stater, 52804
    - Genesis Medical Center - West Campus
  - Davenport, Iowa, Forenede Stater, 52803
    - Genesis Regional Cancer Center at Genesis Medical Center
  - Des Moines, Iowa, Forenede Stater, 50309
    - CCOP - Iowa Oncology Research Association
  - Des Moines, Iowa, Forenede Stater, 50309
    - John Stoddard Cancer Center at Iowa Methodist Medical Center
  - Des Moines, Iowa, Forenede Stater, 50309
    - Medical Oncology and Hematology Associates at John Stoddard Cancer Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Medical Oncology and Hematology Associates at Mercy Cancer Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mercy Cancer Center at Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forenede Stater, 50316
    - John Stoddard Cancer Center at Iowa Lutheran Hospital
  - Des Moines, Iowa, Forenede Stater, 50307
    - Mercy Capitol Hospital
  - Dubuque, Iowa, Forenede Stater, 52001
    - Wendt Regional Cancer Center at Finley Hospital
  - Iowa City, Iowa, Forenede Stater, 52242
    - Holden Comprehensive Cancer Center at University of Iowa
  - Mason City, Iowa, Forenede Stater, 50401
    - Mercy Cancer Center at Mercy Medical Center - North Iowa
  - Missouri Valley, Iowa, Forenede Stater, 51555
    - Alegent Health Community Memorial Hospital
  - Onawa, Iowa, Forenede Stater, 51040
    - Burgess Health Center
  - Sioux City, Iowa, Forenede Stater, 51104
    - St. Luke's Regional Medical Center
  - Sioux City, Iowa, Forenede Stater, 51104
    - Mercy Medical Center - Sioux City
  - Sioux City, Iowa, Forenede Stater, 51101
    - Siouxland Hematology-Oncology Associates
  - West Des Moines, Iowa, Forenede Stater, 50266
    - Medical Oncology and Hematology Associates - West Des Moines
- Kansas
  - Arkansas City, Kansas, Forenede Stater, 67005
    - South Central Kansas Regional Medical Center
  - Chanute, Kansas, Forenede Stater, 66720
    - Cancer Center of Kansas - Chanute
  - Dodge City, Kansas, Forenede Stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forenede Stater, 67042
    - Cancer Center of Kansas, P.A. - El Dorado
  - Kansas City, Kansas, Forenede Stater, 66160
    - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
  - Kingman, Kansas, Forenede Stater, 67068
    - Cancer Center of Kansas - Kingman
  - Liberal, Kansas, Forenede Stater, 67901
    - Southwest Medical Center
  - Newton, Kansas, Forenede Stater, 67114
    - Cancer Center of Kansas - Newton
  - Ottawa, Kansas, Forenede Stater, 66067
    - Cancer Center of Kansas - Ottawa
  - Parsons, Kansas, Forenede Stater, 67357
    - Cancer Center of Kansas, P.A. - Parsons
  - Pratt, Kansas, Forenede Stater, 67124
    - Pratt Cancer Center of Kansas
  - Salina, Kansas, Forenede Stater, 67042
    - Cancer Center of Kansas - Salina
  - Wellington, Kansas, Forenede Stater, 67152
    - Cancer Center of Kansas - Wellington
  - Wichita, Kansas, Forenede Stater, 67214
    - Wesley Medical Center
  - Wichita, Kansas, Forenede Stater, 67214
    - CCOP - Wichita
  - Wichita, Kansas, Forenede Stater, 67214
    - Via Christi Cancer Center at Via Christi Regional Medical Center
  - Wichita, Kansas, Forenede Stater, 67203
    - Associates In Womens Health
  - Wichita, Kansas, Forenede Stater, 67208
    - Cancer Center of Kansas, P.A.
  - Wichita, Kansas, Forenede Stater, 67214
    - Cancer Center of Kansas, P.A. - Wichita
  - Winfield, Kansas, Forenede Stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Bowling Green, Kentucky, Forenede Stater, 42101
    - Cancer Treatment Center at the Medical Center - Bowling Green
  - Lexington, Kentucky, Forenede Stater, 40536
    - Markey Cancer Center at University of Kentucky Chandler Medical Center
  - Lexington, Kentucky, Forenede Stater, 40503
    - Central Baptist Hospital
  - Madisonville, Kentucky, Forenede Stater, 42431
    - Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
- Louisiana
  - Monroe, Louisiana, Forenede Stater, 71210
    - Louisiana State University Health Sciences Center - Monroe
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Tulane Cancer Center
  - Shreveport, Louisiana, Forenede Stater, 71101
    - Veterans Affairs Medical Center - Shreveport
  - Shreveport, Louisiana, Forenede Stater, 71130
    - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
- Maine
  - Bangor, Maine, Forenede Stater, 04401
    - CancerCare of Maine at Eastern Maine Medial Center
  - Lewiston, Maine, Forenede Stater, 04240
    - Central Maine Medical Center
  - Waterville, Maine, Forenede Stater, 04901
    - Maine General Medical Center - Waterville
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - DeCesaris Cancer Institute at Anne Arundel Medical Center
  - Baltimore, Maryland, Forenede Stater, 21287-8936
    - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  - Elkton MD, Maryland, Forenede Stater, 21921
    - Union Hospital Cancer Center at Union Hospital
- Massachusetts
  - Boston, Massachusetts, Forenede Stater, 02115
    - Brigham and Women's Hospital
  - Boston, Massachusetts, Forenede Stater, 02115
    - Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
  - Boston, Massachusetts, Forenede Stater, 02114
    - Massachusetts General Hospital Cancer Center
  - Boston, Massachusetts, Forenede Stater, 02118
    - Cancer Research Center at Boston Medical Center
  - Concord, Massachusetts, Forenede Stater, 01742
    - Bethke Cancer Center at Emerson Hospital
  - Fall River, Massachusetts, Forenede Stater, 02721
    - Hudner Oncology Center at Saint Anne's Hospital
  - Hyannis, Massachusetts, Forenede Stater, 02601
    - Cape Cod Hospital
  - Newton, Massachusetts, Forenede Stater, 02162
    - Newton - Wellesley Hospital
  - Quincy, Massachusetts, Forenede Stater, 02169
    - South Suburban Oncology Center
- Michigan
  - Adrian, Michigan, Forenede Stater, 49221
    - Hickman Cancer Center at Bixby Medical Center
  - Ann Arbor, Michigan, Forenede Stater, 48109
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106-0995
    - St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital
  - Ann Arbor, Michigan, Forenede Stater, 48100
    - CCOP - Michigan Cancer Research Consortium
  - Battle Creek, Michigan, Forenede Stater, 49017
    - Battle Creek Health System
  - Big Rapids, Michigan, Forenede Stater, 49307
    - Mecosta County General Hospital
  - Detroit, Michigan, Forenede Stater, 48202
    - Josephine Ford Cancer Center at Henry Ford Health System
  - Flint, Michigan, Forenede Stater, 48502
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48532
    - Genesys Hurley Cancer Institute
  - Flint, Michigan, Forenede Stater, 48532
    - Great Lakes Cancer Institute at McLaren Regional Medical Center
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - CCOP - Grand Rapids
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Lacks Cancer Center at Saint Mary's Mercy Medical Center
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Spectrum Health Cancer Care - Butterworth Campus
  - Grand Rapids, Michigan, Forenede Stater, 49506
    - Metropolitan Hospital
  - Grand Rapids, Michigan, Forenede Stater, 49506
    - Spectrum Health Hospital - Blodgett Campus
  - Holland, Michigan, Forenede Stater, 49423
    - Holland Community Hospital
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - Bronson Methodist Hospital
  - Kalamazooaa, Michigan, Forenede Stater, 49001
    - Borgess Medical Center
  - Marquette, Michigan, Forenede Stater, 49855
    - Upper Michigan Cancer Center at Marquette General Hospital
  - Muskegon, Michigan, Forenede Stater, 49443
    - Hackley Hospital
  - Petoskey, Michigan, Forenede Stater, 49770
    - Northern Michigan Hospital
  - Port Huron, Michigan, Forenede Stater, 48060
    - Mercy Hospital
  - Saginaw, Michigan, Forenede Stater, 48601
    - Seton Cancer Institute - Saginaw
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Oncology Care Associates, P.L.L.C.
  - Southfield, Michigan, Forenede Stater, 48075
    - Providence Cancer Institute at Providence Hospital - Southfield Campus
  - Traverse City, Michigan, Forenede Stater, 49684
    - Munson Medical Center
  - Warren, Michigan, Forenede Stater, 48903
    - St. John Macomb Hospital
- Minnesota
  - Bemidji, Minnesota, Forenede Stater, 56601
    - MeritCare Clinic - Bemidji
  - Brainerd, Minnesota, Forenede Stater, 56401
    - Brainerd Medical Center
  - Burnsville, Minnesota, Forenede Stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forenede Stater, 55433
    - Mercy Hospital
  - Duluth, Minnesota, Forenede Stater, 55805
    - CCOP - Duluth
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Mary's - Duluth Clinic Cancer Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Miller-Dwan Medical Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Cancer Care Center at St. Luke's Hospital
  - Edina, Minnesota, Forenede Stater, 55435
    - Fairview Southdale Hospital
  - Fridley, Minnesota, Forenede Stater, 55432
    - Mercy and Unity Cancer Center at Mercy and Unity Hospitals
  - Hutchinson, Minnesota, Forenede Stater, 55350
    - Hutchinson Area Health Care
  - Litchfield, Minnesota, Forenede Stater, 55355
    - Meeker County Memorial Hospital
  - Maplewood, Minnesota, Forenede Stater, 55109
    - St. John's Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55415
    - Hennepin County Medical Center - Minneapolis
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Virginia Piper Cancer Institute at Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - Fairview University Medical Center - University Campus
  - Montevideo, Minnesota, Forenede Stater, 56265
    - Chippewa County - Montevideo Hospital
  - Robbinsdale, Minnesota, Forenede Stater, 55422
    - Hubert H. Humphrey Cancer Center at North Memorial Medical Center
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic Cancer Center
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - CCOP - Metro-Minnesota
  - Saint Paul, Minnesota, Forenede Stater, 55101
    - Cancer Care Center at Regions Hospital
  - Shakopee, Minnesota, Forenede Stater, 55379
    - Saint Francis Cancer Center
  - St Paul, Minnesota, Forenede Stater, 55102
    - St. Joseph's Hospital
  - St. Cloud, Minnesota, Forenede Stater, 56303
    - CentraCare Clinic - River Campus
  - St. Cloud, Minnesota, Forenede Stater, 56303
    - Adult and Pediatric Urology, P.L.L.P.
  - St. Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Clinic
  - St. Paul, Minnesota, Forenede Stater, 55102
    - United Hospital
  - Waconia, Minnesota, Forenede Stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forenede Stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Woodwinds Hospital
- Mississippi
  - Jackson, Mississippi, Forenede Stater, 39216
    - Veterans Affairs Medical Center - Jackson
  - Jackson, Mississippi, Forenede Stater, 39216
    - University of Mississippi Medical Center
  - Pascagoula, Mississippi, Forenede Stater, 39581
    - Regional Cancer Center at Singing River Hospital
- Missouri
  - Cape Girardeau, Missouri, Forenede Stater, 63701
    - St. Francis Medical Center
  - Chesterfield, Missouri, Forenede Stater, 63017
    - Saint Luke's Hospital
  - Columbia, Missouri, Forenede Stater, 65203
    - Ellis Fischel Cancer Center at University of Missouri - Columbia
  - Columbia, Missouri, Forenede Stater, 65201
    - Missouri Cancer Associates
  - Gape Girardeau, Missouri, Forenede Stater, 63701
    - Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital
  - Kansas City, Missouri, Forenede Stater, 64131
    - CCOP - Kansas City
  - Springfield, Missouri, Forenede Stater, 65804
    - St. John's Regional Health Center
  - Springfield, Missouri, Forenede Stater, 65807
    - Hulston Cancer Center at Cox Medical Center South
  - St Louis, Missouri, Forenede Stater, 63110
    - Siteman Cancer Center at Barnes-Jewish Hospital
  - St. Louis, Missouri, Forenede Stater, 63131
    - Missouri Baptist Cancer Center
  - St. Louis, Missouri, Forenede Stater, 63141
    - CCOP - St. Louis-Cape Girardeau
  - St. Louis, Missouri, Forenede Stater, 63141
    - David C. Pratt Cancer Center at St. John's Mercy
  - St. Louis, Missouri, Forenede Stater, 63141
    - Center for Cancer Care and Research
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - CCOP - Montana Cancer Consortium
  - Great Falls, Montana, Forenede Stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forenede Stater, 59405
    - Sletten Regional Cancer Institute
- Nebraska
  - Fremont, Nebraska, Forenede Stater, 68025
    - Fremont Area Medical Center
  - Kearney, Nebraska, Forenede Stater, 68847
    - Cancer Center at the Good Samaritan Health Systems
  - Lincoln, Nebraska, Forenede Stater, 68502
    - Bryan LGH Medical Center West
  - Lincoln, Nebraska, Forenede Stater, 68510
    - Cancer Resource Center - Lincoln
  - Lincoln, Nebraska, Forenede Stater, 68510
    - St. Elizabeth Regional Medical Center
  - Omaha, Nebraska, Forenede Stater, 68106
    - CCOP - Missouri Valley Cancer Consortium
  - Omaha, Nebraska, Forenede Stater, 68114
    - Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha
  - Omaha, Nebraska, Forenede Stater, 68124
    - Bergan Mercy Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Alegent Health - Immanuel Medical Center
  - Omaha, Nebraska, Forenede Stater, 68131
    - Cancer Center at Creighton University Medical Center
  - Papillion, Nebraska, Forenede Stater, 68046
    - Midlands Cancer Center at Midlands Community Hospital
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89106
    - CCOP - Southern Nevada Cancer Research Foundation
  - Las Vegas, Nevada, Forenede Stater, 89109
    - Sunrise Hospital and Medical Center
  - Las Vegas, Nevada, Forenede Stater, 89102
    - University Medical Center of Southern Nevada
  - Reno, Nevada, Forenede Stater, 89502
    - Washoe Cancer Services at Washoe Medical Center - Reno
- New Hampshire
  - Lebanon, New Hampshire, Forenede Stater, 03756
    - Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
- New Jersey
  - Camden, New Jersey, Forenede Stater, 08103
    - Cancer Institute of New Jersey at the Cooper University Hospital
  - Hackensack, New Jersey, Forenede Stater, 07601
    - CCOP - Northern New Jersey
  - Long Branch, New Jersey, Forenede Stater, 07740
    - Monmouth Medical Center
  - Millville, New Jersey, Forenede Stater, 08332
    - South Jersey Healthcare Regional Cancer Center
  - Montclair, New Jersey, Forenede Stater, 07042
    - Cancer Center at the Mountainside Hospital
  - Mount Holly, New Jersey, Forenede Stater, 08060
    - Fox Chase Virtua Health Cancer Program - Marlton
  - Newark, New Jersey, Forenede Stater, 07112
    - Newark Beth Israel Medical Center
  - Pomona, New Jersey, Forenede Stater, 08240
    - Atlantic City Medical Center - Mainland Division
  - Red Bank, New Jersey, Forenede Stater, 07701
    - Booker Cancer Center at Riverview Medical Center
  - Toms River, New Jersey, Forenede Stater, 08755
    - Community Medical Center
  - Trenton, New Jersey, Forenede Stater, 08611
    - Fox Chase Cancer Center at St. Francis Medical Center
  - Trenton, New Jersey, Forenede Stater, 08618
    - Capital Health System Regional Cancer Center
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87106
    - University of New Mexico Cancer Research and Treatment Center
  - Albuquerque, New Mexico, Forenede Stater, 87108
    - Lovelace Medical Center at Lovelace Sandia Health System
  - Albuquerque, New Mexico, Forenede Stater, 87106
    - Hematology-Oncology Associates, PC
- New York
  - Brooklyn, New York, Forenede Stater, 11203
    - SUNY downstate Medical Center
  - Brooklyn, New York, Forenede Stater, 11215
    - New York Methodist Hospital
  - Clifton Springs, New York, Forenede Stater, 14432
    - Finger Lakes Hematology and Oncology
  - Cooperstown, New York, Forenede Stater, 13326
    - Louis Busch Hager Cancer Center at Mary Imogene Bassett Hospital
  - Harris, New York, Forenede Stater, 12742
    - Catskill Regional Medical Center
  - Manhasset, New York, Forenede Stater, 11030
    - CCOP - North Shore University Hospital
  - New York, New York, Forenede Stater, 10021
    - New York Weill Cornell Cancer Center at Cornell University
  - Rochester, New York, Forenede Stater, 14642
    - James P. Wilmot Cancer Center at University of Rochester Medical Center
  - Rochester, New York, Forenede Stater, 14620
    - Highland Hospital of Rochester
  - Syracuse, New York, Forenede Stater, 13210
    - Veterans Affairs Medical Center - Syracuse
  - Syracuse, New York, Forenede Stater, 13057
    - CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.
  - Syracuse, New York, Forenede Stater, 13215
    - Community General Hospital of Greater Syracuse
  - Syracuse, New York, Forenede Stater, 13210
    - Crouse Hospital
- North Carolina
  - Asheboro, North Carolina, Forenede Stater, 27203
    - Randolph Hospital
  - Charlotte, North Carolina, Forenede Stater, 28233
    - Presbyterian Cancer Center at Presbyterian Hospital
  - Charlotte, North Carolina, Forenede Stater, 28203
    - Blumenthal Cancer Center at Carolinas Medical Center
  - Eden, North Carolina, Forenede Stater, 27288
    - John Smith, Jr./Dalton McMichael Cancer Center at Morehead Memorial Hospital
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Wayne Radiation Oncology
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Wayne Memorial Hospital, Incorporated
  - Greensboro, North Carolina, Forenede Stater, 27401
    - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
  - Kinston, North Carolina, Forenede Stater, 28501
    - Lenoir Memorial Cancer Center
  - Reidsville, North Carolina, Forenede Stater, 27320
    - Annie Penn Cancer Center
  - Wilmington, North Carolina, Forenede Stater, 28401
    - Zimmer Cancer Center at New Hanover Regional Medical Center
  - Wilson, North Carolina, Forenede Stater, 27893
    - Wilson Medical Center
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Forsyth Regional Cancer Center at Forsyth Medical Center
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Medcenter One Health System
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Mid Dakota Clinic, P.C.
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Bismarck Cancer Center
  - Bismarck, North Dakota, Forenede Stater, 58501
    - St. Alexius Medical Center
  - Fargo, North Dakota, Forenede Stater, 58122
    - CCOP - MeritCare Hospital
  - Fargo, North Dakota, Forenede Stater, 58122
    - MeritCare Medical Group
  - Grand Forks, North Dakota, Forenede Stater, 58201
    - Altru Cancer Center at Altru Hospital
  - Minot, North Dakota, Forenede Stater, 58701
    - Trinity Cancer Care Center
- Ohio
  - Akron, Ohio, Forenede Stater, 44307
    - McDowell Cancer Center at Akron General Medical Center
  - Akron, Ohio, Forenede Stater, 44304
    - Akron City Hospital at Summa Health System
  - Canton, Ohio, Forenede Stater, 44708
    - University Hospitals Ireland Cancer Center at Mercy Medical Center
  - Chillicothe, Ohio, Forenede Stater, 54601
    - Adena Regional Medical Center
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic Taussig Cancer Center
  - Cleveland, Ohio, Forenede Stater, 44109
    - MetroHealth's Cancer Care Center at MetroHealth Medical Center
  - Cleveland, Ohio, Forenede Stater, 44106
    - Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University
  - Cleveland, Ohio, Forenede Stater, 44112
    - Huron Hospital Cancer Care Center
  - Cleveland, Ohio, Forenede Stater, 44119
    - Euclid Hospital
  - Columbus, Ohio, Forenede Stater, 43215
    - CCOP - Columbus
  - Columbus, Ohio, Forenede Stater, 43228
    - Doctors Hospital at Ohio Health
  - Columbus, Ohio, Forenede Stater, 43214
    - Riverside Methodist Hospital Cancer Care
  - Columbus, Ohio, Forenede Stater, 43215
    - Grant Riverside Cancer Services
  - Columbus, Ohio, Forenede Stater, 43222
    - Mount Carmel West Hospital
  - Columbus, Ohio, Forenede Stater, 43210
    - Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University
  - Dayton, Ohio, Forenede Stater, 45428
    - Veterans Affairs Medical Center - Dayton
  - Dayton, Ohio, Forenede Stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forenede Stater, 45405
    - Grandview Hospital
  - Dayton, Ohio, Forenede Stater, 45406
    - Good Samaritan Hospital
  - Dayton, Ohio, Forenede Stater, 45415
    - Samaritan North Cancer Care Center
  - Dayton, Ohio, Forenede Stater, 45429
    - CCOP - Dayton
  - Delaware, Ohio, Forenede Stater, 43015
    - Grady Memorial Hospital
  - Kettering, Ohio, Forenede Stater, 45429
    - Charles F. Kettering Memorial Hospital
  - Lancaster, Ohio, Forenede Stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forenede Stater, 45804
    - Lima Memorial Hospital
  - Lima, Ohio, Forenede Stater, 45801
    - St. Rita's Medical Center
  - Marietta, Ohio, Forenede Stater, 45750
    - Strecker Cancer Center at Marietta Memorial Hospital
  - Maumee, Ohio, Forenede Stater, 43537
    - St. Luke's Hospital
  - Mayfield Heights, Ohio, Forenede Stater, 44124
    - Hillcrest Cancer Center at Hillcrest Hospital
  - Middletown, Ohio, Forenede Stater, 45044
    - Middletown Regional Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Licking Memorial Cancer Care Program at Licking Memorial Hospital
  - Oregon, Ohio, Forenede Stater, 43616
    - St. Charles Mercy Hospital
  - Salem, Ohio, Forenede Stater, 44460
    - Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford
  - Sandusky, Ohio, Forenede Stater, 44870
    - Firelands Regional Medical Center
  - Springfield, Ohio, Forenede Stater, 45505
    - Community Hospital of Springfield and Clark County
  - Springfield, Ohio, Forenede Stater, 45504
    - Mercy Medical Center Oncology Unit
  - Sylvania, Ohio, Forenede Stater, 43560
    - Promedica Cancer Center at Flower Hospital
  - Tiffin, Ohio, Forenede Stater, 44883
    - Mercy Hospital of Tiffin
  - Toledo, Ohio, Forenede Stater, 43608
    - St. Vincent Mercy Medical Center
  - Toledo, Ohio, Forenede Stater, 43606
    - Toledo Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - CCOP - Toledo Community Hospital
  - Toledo, Ohio, Forenede Stater, 43614
    - Medical College of Ohio Cancer Institute
  - Toledo, Ohio, Forenede Stater, 43623
    - Toledo Clinic, Incorporated
  - Troy, Ohio, Forenede Stater, 45373
    - UVMC Cancer Care Center at Upper Valley Medical Center
  - Warrensville Heights, Ohio, Forenede Stater, 44122
    - South Pointe Hospital Cancer Care Center
  - Westerville, Ohio, Forenede Stater, 43081
    - Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital
  - Wooster, Ohio, Forenede Stater, 44691
    - Cancer Treatment Center
  - Xenia, Ohio, Forenede Stater, 45385
    - Ruth G. McMillan Cancer Center at Greene Memorial Hospital
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis - Good Samaritan Hospital
- Oklahoma
  - Tulsa, Oklahoma, Forenede Stater, 74136
    - Natalie Warren Bryant Cancer Center at St. Francis Hospital
  - Tulsa, Oklahoma, Forenede Stater, 74104
    - LaFortune Cancer Center at St. John Health System
- Oregon
  - Glesham, Oregon, Forenede Stater, 97030
    - Legacy Mount Hood Medical Center
  - Milwaukie, Oregon, Forenede Stater, 97222
    - Providence Milwaukie Hospital
  - Portland, Oregon, Forenede Stater, 97225
    - CCOP - Columbia River Oncology Program
  - Portland, Oregon, Forenede Stater, 97225
    - Providence St. Vincent Medical Center
  - Portland, Oregon, Forenede Stater, 97210
    - Comprehensive Cancer Center at Legacy Good Samaritan Hospital & Medical Center
  - Portland, Oregon, Forenede Stater, 97213
    - Providence Cancer Center at Providence Portland Medical Center
  - Portland, Oregon, Forenede Stater, 97227
    - Institute of Oncology at Vilnius University
  - Portland, Oregon, Forenede Stater, 97232
    - Kaiser Permanente Health Care - Portland
  - Portland, Oregon, Forenede Stater, 97239
    - Cancer Institute at Oregon Health and Science University
  - Salem, Oregon, Forenede Stater, 97309
    - Salem Hospital Regional Cancer Center
  - Tualatin, Oregon, Forenede Stater, 97062
    - Legacy Meridian Park Hospital
- Pennsylvania
  - Allentown, Pennsylvania, Forenede Stater, 18105
    - John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital
  - Bethlehem, Pennsylvania, Forenede Stater, 18015
    - St. Luke's Hospital Cancer Center
  - Bryn Mawr, Pennsylvania, Forenede Stater, 19010
    - Bryn Mawr Hospital
  - Danville, Pennsylvania, Forenede Stater, 17822-2001
    - Geisinger Medical Center
  - Drexel Hill, Pennsylvania, Forenede Stater, 19026
    - Delaware County Regional Cancer Center at Delaware County Memorial Hospital
  - Hershey, Pennsylvania, Forenede Stater, 17033-0850
    - Penn State Cancer Institute at Milton S. Hershey Medical Center
  - Langhorne, Pennsylvania, Forenede Stater, 19047
    - St. Mary Regional Cancer Center
  - Lewistown, Pennsylvania, Forenede Stater, 17044
    - Lewistown Hospital
  - Paoli, Pennsylvania, Forenede Stater, 19301
    - Cancer Center at Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19111-2497
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19141
    - Albert Einstein Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Joan Karnell Cancer Center at Pennsylvania Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny Cancer Center at Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15219
    - Mercy Hospital of Pittsburgh
  - Pittsburgh, Pennsylvania, Forenede Stater, 15224-1791
    - Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
  - Pottstown, Pennsylvania, Forenede Stater, 19464
    - Pottstown Memorial Regional Cancer Center
  - Reading, Pennsylvania, Forenede Stater, 19604
    - St. Joseph Medical Center
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Guthrie Medical Center - Sayre
  - Scranton, Pennsylvania, Forenede Stater, 18501
    - Mercy Hospital Cancer Center - Scranton
  - State College, Pennsylvania, Forenede Stater, 16801
    - Geisinger Medical Group
  - State College, Pennsylvania, Forenede Stater, 16803
    - Mount Nittany Medical Center
  - West Reading, Pennsylvania, Forenede Stater, 19612
    - Reading Hospital and Medical Center
  - Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
    - Geisinger Wyoming Valley Medical Center
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - CCOP - MainLine Health
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - Lankenau Cancer Center at Lankenau Hospital
- South Carolina
  - Greenville, South Carolina, Forenede Stater, 29615
    - CCOP - Greenville
  - Greenville, South Carolina, Forenede Stater, 29601
    - Bon Secours St. Francis Health System
  - Greenville, South Carolina, Forenede Stater, 29605
    - Greenville Hospital System Cancer Center
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forenede Stater, 57105
    - Medical X-Ray Center
  - Sioux Falls, South Dakota, Forenede Stater, 57104
    - Sioux Valley Hospital and University of South Dakota Medical Center
  - Sioux Falls, South Dakota, Forenede Stater, 57105
    - Avera McKennan Hospital and University Health Center
- Tennessee
  - Memphis, Tennessee, Forenede Stater, 38146
    - Baptist Centers for Cancer Care
- Texas
  - Amarillo, Texas, Forenede Stater, 79106
    - Harrington Cancer Center
  - Bryan, Texas, Forenede Stater, 77802
    - St. Joseph Regional Cancer Center
  - Fort Sam Houston, Texas, Forenede Stater, 78234
    - Brooke Army Medical Center
  - Houston, Texas, Forenede Stater, 77030
    - M.D. Anderson Cancer Center at University of Texas
  - Lackland AFB, Texas, Forenede Stater, 78236
    - Wilford Hall Medical Center
  - Lubbock, Texas, Forenede Stater, 79410
    - Joe Arrington Cancer Research and Treatment Center
  - San Antonio, Texas, Forenede Stater, 78229
    - Cancer Therapy and Research Center
  - San Antonio, Texas, Forenede Stater, 78209
    - Veterans Affairs Medical Center - San Antonio (Murphy)
  - San Antonio, Texas, Forenede Stater, 78229
    - University Hospital - San Antonio
  - San Antonio, Texas, Forenede Stater, 78284
    - University of Texas Health Science Center at San Antonio
- Utah
  - Murray, Utah, Forenede Stater, 84107
    - Cottonwood Hospital Medical Center
  - Ogden, Utah, Forenede Stater, 84403
    - McKay-Dee Hospital Center
  - Provo, Utah, Forenede Stater, 84603
    - Utah Valley Regional Medical Center - Provo
  - Salt Lake City, Utah, Forenede Stater, 84143
    - LDS Hospital
  - Salt Lake City, Utah, Forenede Stater, 84112
    - Huntsman Cancer Institute at University of Utah
  - Salt Lake City, Utah, Forenede Stater, 84106
    - Utah Cancer Specialists at UCS Cancer Center
  - St. George, Utah, Forenede Stater, 84770
    - Dixie Regional Medical Center
- Vermont
  - Berlin, Vermont, Forenede Stater, 05602
    - Mountainview Medical
  - Burlington, Vermont, Forenede Stater, 05401
    - Fletcher Allen Health Care - University Health Center Campus
- Virginia
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Regional Medical Center
  - Hampton, Virginia, Forenede Stater, 23666
    - Virginia Oncology Associates - Hampton
  - Richmond, Virginia, Forenede Stater, 23226
    - Bon Secours Cancer Care at St. Mary's Hospital
- Washington
  - Bellingham, Washington, Forenede Stater, 98225
    - St. Joseph Hospital Community Cancer Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Olympic Hematology and Oncology
  - Everett, Washington, Forenede Stater, 98201
    - Providence Cancer Institute at Providence Everett Medical Center - Pacific Campus
  - Mt. Vernon, Washington, Forenede Stater, 98273
    - Cancer Care Center at Skagit Valley Hospital
  - Seattle, Washington, Forenede Stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forenede Stater, 98101
    - CCOP - Virginia Mason Research Center
  - Seattle, Washington, Forenede Stater, 98104
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forenede Stater, 98195
    - University Cancer Center at University of Washington Medical Center
  - Seattle, Washington, Forenede Stater, 98104
    - Group Health Central Hospital
  - Seattle, Washington, Forenede Stater, 98114
    - Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
  - Spokane, Washington, Forenede Stater, 99202
    - Cancer Care Northwest - Spokane South
  - Tacoma, Washington, Forenede Stater, 98431
    - Madigan Army Medical Center
  - Vancouver, Washington, Forenede Stater, 98668
    - Cancer Center at Southwest Washington Medical Center
  - Wenatchee, Washington, Forenede Stater, 98801
    - Central Washington Hospital
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Clinic
- West Virginia
  - Morgantown, West Virginia, Forenede Stater, 26506
    - Mary Babb Randolph Cancer Center at West Virginia University Hospitals
  - Parkersburg, West Virginia, Forenede Stater, 26101
    - Camden-Clark Memorial Hospital
- Wisconsin
  - Eau Claire, Wisconsin, Forenede Stater, 54702
    - Luther Mildelfort Hospital
  - Eau Claire, Wisconsin, Forenede Stater, 54702
    - Midelfort Clinic - Luther
  - Fond Du Lac, Wisconsin, Forenede Stater, 54935
    - Central Wisconsin Cancer Program at Agnesian Health Care
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Green Bay Oncology, Limited at St. Mary's Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54301-3526
    - Green Bay Oncology, Limited at St. Vincent Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54301
    - St. Vincent Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - St. Mary's Hospital Medical Center
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center
  - Madison, Wisconsin, Forenede Stater, 53792
    - University of Wisconsin Comprehensive Cancer Center
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Bay Area Cancer Care Center at Bay Area Medical Center
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Marshfield Clinic - Marshfield Center
  - Menomonee Falls, Wisconsin, Forenede Stater, 53051
    - Community Memorial Hospital
  - Milwaukee, Wisconsin, Forenede Stater, 53295
    - Veterans Affairs Medical Center - Milwaukee (Zablocki)
  - Milwaukee, Wisconsin, Forenede Stater, 53226
    - Medical College of Wisconsin Cancer Center
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Vince Lombardi Cancer Clinic at St. Luke's Medical Center
  - Racine, Wisconsin, Forenede Stater, 53405
    - All Saints Cancer Center at All Saints Healthcare
  - West Allis, Wisconsin, Forenede Stater, 53227
    - West Allis Memorial Hospital
Sydafrika
- - Pretoria, 0001, Sydafrika
    - Pretoria Academic Hospital

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år til 120 år (VOKSEN, OLDER_ADULT)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

SYGDOMS KARAKTERISTIKA:

Histologisk bekræftet primært planocellulært, basaloid- eller kloakogent karcinom i analkanalen, bortset fra carcinom in situ
- T2-4, enhver N, M0 (trin II eller III)
Intet lokalt eller regionalt tilbagefald efter lokal excision eller abdominal peritoneal resektion

PATIENT KARAKTERISTIKA:

Alder:

18 og derover

Ydeevnestatus:

Karnofsky 60-100 %

Forventede levealder:

Ikke specificeret

Hæmatopoietisk:

WBC mindst 4.000/mm^3
Absolut neutrofiltal mindst 1.800/mm^3
Blodpladetal mindst 100.000/mm^3
Hæmoglobin mindst 10 g/dL

Hepatisk:

Bilirubin mindre end 1,4 mg/dL

Nyre:

Kreatinin ikke større end 1,5 mg/dL ELLER
Kreatininclearance mindst 80 ml/min

Kardiovaskulær:

Ingen ukompenseret hjertesygdom
Intet ukontrolleret højt blodtryk

Andet:

Ingen AIDS
Ingen aktiv systemisk infektion
Ingen ukontrolleret diabetes
Ingen anden tidligere malignitet inden for de seneste 5 år undtagen non-melanom hudkræft
Ingen psykisk tilstand, der ville udelukke studiedeltagelse
Ikke gravid eller ammende
Fertile patienter skal bruge effektiv prævention

FORUDSÆTNING SAMTYDLIG TERAPI:

Biologisk terapi:

Tidligere epoetin alfa tilladt i stedet for blodtransfusioner

Kemoterapi:

Mindst 5 år siden tidligere kemoterapi

Endokrin terapi:

Ikke specificeret

Strålebehandling:

Mindst 5 år siden tidligere strålebehandling

Kirurgi:

Ingen forudgående operation af analkanalen undtagen biopsi af undersøgelsesstedet

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: BEHANDLING
Tildeling: TILFÆLDIGT

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Radiation Therapy Oncology Group

Samarbejdspartnere

National Cancer Institute (NCI)

Eastern Cooperative Oncology Group

Southwest Oncology Group

Cancer and Leukemia Group B

North Central Cancer Treatment Group

Efterforskere

Studiestol: Joel E. Tepper, MD, UNC Lineberger Comprehensive Cancer Center

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Ben-Josef E, Moughan J, Ajani JA, Flam M, Gunderson L, Pollock J, Myerson R, Anne R, Rosenthal SA, Willett C. Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11. J Clin Oncol. 2010 Dec 1;28(34):5061-6. doi: 10.1200/JCO.2010.29.1351. Epub 2010 Oct 18.
Glynne-Jones R, Mawdsley S. Anal cancer: is neoadjuvant cisplatin chemotherapy or chemoradiotherapy friend or foe? Nat Clin Pract Oncol. 2008 Dec;5(12):692-3. doi: 10.1038/ncponc1258. Epub 2008 Oct 14.
Gunderson LL, Winter KA, Ajani JA, et al.: Long-term update of U.S. GI intergroup RTOG 98-11 phase III trial for anal carcinoma: disease-free and overall survival with RT+5FU-mitomycin versus RT+5FU-cisplatin. [Abstract] J Clin Oncol 29 (Suppl 15): A-4005, 2011.
Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG. Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11). Cancer. 2010 Sep 1;116(17):4007-13. doi: 10.1002/cncr.25188.
Gunderson LL, Moughan J, Ajani JA, et al.: Anal carcinoma: Impact of TN category of disease on survival, disease relapse, and colostomy failure in U.S. GI Intergroup RTOG 98-11 phase III trial. [Abstract] American Society of Clinical Oncology 2010 Gastrointestinal Cancers Symposium, 22-24 January 2010, Orlando, Florida. A-285, 2010.
Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG. US intergroup anal carcinoma trial: tumor diameter predicts for colostomy. J Clin Oncol. 2009 Mar 1;27(7):1116-21. doi: 10.1200/JCO.2008.19.6857. Epub 2009 Jan 12.
Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett C. Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA. 2008 Apr 23;299(16):1914-21. doi: 10.1001/jama.299.16.1914.
Ajani JA, Winter KA, Gunderson LL, et al.: Intergroup RTOG 98-11: a phase III randomized study of 5-fluorouracil (5-FU), mitomycin, and radiotherapy versus 5-fluorouracil, cisplatin and radiotherapy in carcinoma of the anal canal. [Abstract] J Clin Oncol 24 (Suppl 18): A-4009, 2006.
Gunderson LL, Winter KA, Ajani JA, et al.: Intergroup RTOG 9811 phase III comparison of chemoradiation with 5-FU and mitomycin vs 5-FU and cisplatin for anal canal carcinoma: impact on disease-free, overall and colostomy-free survival. [Abstract] Int J Radiat Oncol Biol Phys 66 (3 Suppl 1): A-43, S24, 2006.
Gunderson LL, Winter KA, Ajani JA, Pedersen JE, Moughan J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG. Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin. J Clin Oncol. 2012 Dec 10;30(35):4344-51. doi: 10.1200/JCO.2012.43.8085. Epub 2012 Nov 13.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. oktober 1998

Primær færdiggørelse (FAKTISKE)

1. oktober 2005

Studieafslutning (FAKTISKE)

1. december 2016

Datoer for studieregistrering

Først indsendt

1. november 1999

Først indsendt, der opfyldte QC-kriterier

26. januar 2003

Først opslået (SKØN)

27. januar 2003

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (SKØN)

4. januar 2017

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

30. december 2016

Sidst verificeret

1. december 2016

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

RTOG-9811
CDR0000066667
CALGB-89808
ECOG-R9811
NCCTG-R9811
SWOG-R9811
GUMC-00125

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Anal kræft

Cairo University

Rekruttering

IFOC Sammenlignet Med LIFT ved Høj Anal Fistel: Et Pilot RCT

Høj anal fistel | Anal fistelkirurgi

Egypten
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Aktiv, ikke rekrutterende

Lavere dosis kemoradiation i behandling af patienter med tidligt stadie af anal kræft, DECREASE-undersøgelsen

Anal basaloid karcinom | Anal Canal Cloacogenic Carcinom | Anal kanal planocellulært karcinom | Anal margin planocellulært karcinom | Stadie I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

Forenede Stater
The Cleveland Clinic
Bard Ltd

Afsluttet

Sammenlignende undersøgelse mellem to fækale styringssystemer

Anal erosion

Forenede Stater
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Afsluttet

LET-IMPT og standardkemoterapi til behandling af patienter med nyligt diagnosticeret trin I-III analkanalpladecellekræft

Stage III anal cancer AJCC v8 | Anal kanal planocellulært karcinom | Stadie IIB Anal Cancer AJCC v8 | Stadie IIIA anal cancer AJCC v8 | Stadie IIIB anal cancer AJCC v8 | Stadie IIIC anal cancer AJCC v8 | Stadie I Anal Cancer AJCC v8 | Stadie II anal kræft AJCC v8 | Stage IIA Anal Cancer AJCC v8

Forenede Stater
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Aktiv, ikke rekrutterende

Nivolumab efter kombineret modalitetsterapi til behandling af patienter med højrisiko trin II-IIIB analcancer

Anal basaloid karcinom | Anal Canal Cloacogenic Carcinom | Stage III anal cancer AJCC v8 | Anal margin planocellulært karcinom | Stadie IIB Anal Cancer AJCC v8

Forenede Stater, Canada
National Cancer Institute (NCI)

Aktiv, ikke rekrutterende

EA2176: Fase 3 klinisk forsøg med Carboplatin og Paclitaxel +/- Nivolumab hos patienter med metastatisk analcancer

Anal basaloid karcinom | Anal Canal Cloacogenic Carcinom | Metastatisk anal planocellulært karcinom | Tilbagevendende anal planocellulært karcinom | Stage III anal cancer AJCC v8 | Stadie IV analkræft AJCC v8 | Uoperabelt anal planocellulært karcinom

Forenede Stater
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Afsluttet

4-punkts terapiresponsscore med PET/CT for anal pladecellekræft

Anal planocellulært karcinom | Stage III anal cancer AJCC v8 | Stadie IIB Anal Cancer AJCC v8 | Stadie IIIA anal cancer AJCC v8 | Stadie IIIB anal cancer AJCC v8 | Stadie IIIC anal cancer AJCC v8 | Stadie I Anal Cancer AJCC v8 | Stadie II anal kræft AJCC v8 | Stage IIA Anal Cancer AJCC v8 | Trin 0 Anal Cancer...

Forenede Stater
Hospices Civils de Lyon

Afsluttet

Vurdering af den prædiktive værdi af eddikesyretesten i kirurgisk tilstand til påvisning af dysplastiske læsioner hos patienter med anal kondylomatose

Anal kondylom

Frankrig
Sun Yat-sen University

Afsluttet

Neoadjuverende PD-1-blokade kombineret med kemoterapi efterfulgt af samtidig immunradioterapi til lokalt avancerede analkanalpladecellekarcinompatienter

Anal Canal Cancer | Anal planocellulært karcinom | Anal kræft | Anal Cancer Stadium I | Anal Cancer Stadium II | Anal Cancer Stadium III

Kina
Cairo University

Rekruttering

TROPIS versus coring out fistulektomi ved høj anal fistel (TROCO-HAF)

Høj anal fistel

Egypten

Kliniske forsøg med fluorouracil

Guangdong Provincial People's Hospital
Shanghai Henlius Biotech

Aktiv, ikke rekrutterende

En randomiseret kontrolleret undersøgelse af serplulimab kombineret med kemoterapi til lokal avanceret gastrisk adenokarcinom

Mavekræft stadie III

Kina
Combined Military Hospital (CMH) institute of Medical...

Rekruttering

SAMMENLIGNING AF EFFEKTIVITET AF INTRALESIONALE INJEKTIONER AF 5-FLUORURACIL ALENE VERSUS DETS KOMBINATION MED KRYOTERAPI I BEHANDLINGEN AF KELOIDER

Keloider

Pakistan
Washington University School of Medicine
The Joseph Sanchez Foundation

Rekruttering

5-Fluorouracil Respons- og Optimering Studie (FROST-forsøget)

Planocellulært karcinom i hoved og hals | Tilbagevendende planocellulært karcinom i hoved og hals | Metastatisk planocellulært karcinom

Forenede Stater
Northern Jiangsu People's Hospital

Rekruttering

Effektivitet og sikkerhed af postoperativ adjuvant hepatic arterial infusion kemoterapi med mFOLFOX i hepatocellular karcinom med højrisiko recidivfaktorer

Hepatocellulært karcinom (HCC)

Kina
M.D. Anderson Cancer Center

Rekruttering

Et pilot klinisk forsøg, der sammenligner topisk fluorouracil med fluorouracil plus calcipotriene feltbehandlinger hos patienter med flere aktiniske keratoser

Flere aktiniske keratoser

Forenede Stater
Instituto de Oftalmología Fundación Conde de Valenciana

Rekruttering

Anvendelse af intralæsional 5-fluorouracil til behandling af hypertrofe ansigtsar i den periokulære region forårsaget af traumer og kirurgiske indgreb hos personer over 18 år (AI5FMHFSPRFSOE)

Ardannelse i ansigtet

Mexico
Zhongshan Ophthalmic Center, Sun Yat-sen University

Rekruttering

Effektevaluering af 5-fluorouracil som en adjuvans til endoskopisk dacryocystorhinostomi ved håndtering af primær erhvervet nasolacrimal kanalobstruktion med lille lacrimal sac: en randomiseret kontrolleret undersøgelse

Primær erhvervet nasolacrimal kanalobstruktion

Kina
CStone Pharmaceuticals

Aktiv, ikke rekrutterende

En undersøgelse af CS1001 hos personer med esophageal pladecellecarcinom

Ikke-operabelt lokalt avanceret, tilbagevendende eller metastatisk spiserørspladecellecarcinom

Kina
Sun Yat-sen University
Zhejiang Cancer Hospital; Fudan University; Peking University Cancer Hospital... og andre samarbejdspartnere

Ukendt

Adjuverende kemoterapi hos patienter med lokoregionalt avanceret nasopharyngealt karcinom

Nasopharyngealt karcinom

Kina
Sun Yat-sen University

Ukendt

Neoadjuverende FOLFOX6 kemoterapi med eller uden stråling ved endetarmskræft (FOWARC)

Endetarmskræft

Kina

Kemoterapi Plus strålebehandling til behandling af patienter med trin II eller trin III anal cancer

En fase III randomiseret undersøgelse af 5-Fluorouracil, Mitomycin-C og strålebehandling versus 5-fluorouracil, cisplatin og strålebehandling ved karcinom i analkanalen

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart

Primær færdiggørelse (FAKTISKE)

Studieafslutning (FAKTISKE)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (SKØN)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (SKØN)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Anal kræft

Kliniske forsøg med fluorouracil

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Bahrain

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer