- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT00085826
Et fase III-studie af effekten af Taxotere/Aptosyn versus Taxotere/Placebo hos ikke-småcellet lungekræftpatienter
En fase III, randomiseret, dobbeltblind, multicenterundersøgelse af effekten af Taxotere (Docetaxel) i kombination med Aptosyn (Exisulind) versus Taxotere (Docetaxel) og placebo hos patienter med ikke-småcellet lungekræft (NSCLC) efter svigt af Tidligere platinbaseret kemoterapi
Taxotere er blevet godkendt af FDA og betragtes som en standardbehandling til patienter med lungekræft, som har fejlet tidligere platinholdige regimer. Hovedformålet med denne forskningsundersøgelse er at bestemme, om Aptosyn, når det gives i kombination med Taxotere, vil resultere i forlænget overlevelse sammenlignet med Taxotere alene.
Denne undersøgelse vil også hjælpe med at bestemme tumorresponsrater og sikkerhedsprofilen for Aptosyn i kombination med Taxotere.
Denne undersøgelse er afsluttet, og en publikation afventer.
Studieoversigt
Undersøgelsestype
Tilmelding
Fase
- Fase 3
Kontakter og lokationer
Studiesteder
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Alabama
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Birmingham, Alabama, Forenede Stater, 35205
- Birmingham Hematology Oncology Associates
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Birmingham, Alabama, Forenede Stater, 35235
- Birmingham Hematology and Oncology Associates, LLC
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Arizona
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Flagstaff, Arizona, Forenede Stater, 86001
- Northern Arizona Hematology and Oncology Associates
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Phoenix, Arizona, Forenede Stater, 85012
- Hematology & Oncology Associates
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Sedona, Arizona, Forenede Stater, 86336
- Northern Arizona Hematology & Oncology Associates
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Tucson, Arizona, Forenede Stater, 85715
- Arizona Clinical Research Center
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Arkansas
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Little Rock, Arkansas, Forenede Stater, 72207
- Arkansas Oncology Associates, PA
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California
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Fountain Valley, California, Forenede Stater, 92708
- Pacific Coast Hematology/Oncology Medical Group, Inc.
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Greenbrae, California, Forenede Stater, 94904
- California Cancer Care, Inc.
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San Diego, California, Forenede Stater, 92123
- Sharp Clinical Oncology Research
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SanDiego, California, Forenede Stater, 92121
- Scripps Cancer Center
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Santa Rosa, California, Forenede Stater, 95403
- Redwood Regional Medical Group
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Colorado
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Boulder, Colorado, Forenede Stater, 80304
- Rocky Mountain Cancer Center
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Colorado Springs, Colorado, Forenede Stater, 80909
- Rocky Mountain Cancer Centers
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Denver, Colorado, Forenede Stater, 80218
- RMCC
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Englewood, Colorado, Forenede Stater, 80110
- 12. Rocky Mountain Cancer Centers-Englewood
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Englewood, Colorado, Forenede Stater, 80110
- Rocky Mountain Cancer Centers
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Fort Collins, Colorado, Forenede Stater, 80524
- Rocky Mountain Cancer Centers
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Littleton, Colorado, Forenede Stater, 80120
- Rocky Mountain Cancer Centers
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Thornton, Colorado, Forenede Stater, 80260
- Rocky Mountain Cancer Centers
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Florida
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Boca Raton, Florida, Forenede Stater, 33428
- Boca Raton Comprehensive Cancer Center
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Boca Raton, Florida, Forenede Stater, 33428
- Comprehensive Cancer Care Specialists at Boca Raton
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Jacksonville, Florida, Forenede Stater, 32207
- Florida Oncology Associates
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Jacksonville, Florida, Forenede Stater, 32204
- North Florida Hematology & Oncology Association
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Lauderhill, Florida, Forenede Stater, 33319
- South Florida Oncology & Hematology Consultants
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New Port Richey, Florida, Forenede Stater, 34655
- Florida Cancer Institute
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Ocala, Florida, Forenede Stater, 34474
- Ocala Oncology Center
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Orange Park, Florida, Forenede Stater, 32073
- Florida Oncology Associates
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Orlando, Florida, Forenede Stater, 32806
- Cancer Centers of Florida
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Plantation, Florida, Forenede Stater, 33324
- Lauderhill Lakes
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Illinois
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Evanston, Illinois, Forenede Stater, 60201
- Evanston Northwestern Healthcare
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Niles, Illinois, Forenede Stater, 60714
- Northwest Medical Specialists, PC
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Peoria, Illinois, Forenede Stater, 61602
- Onc/Hem Associates of Central Illinois
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Skokie, Illinois, Forenede Stater, 60077
- Hematology Oncology Associates of Illinois
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Indiana
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Indianapolis, Indiana, Forenede Stater, 46227
- Central Indiana Cancer Centers
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Iowa
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Cedar Rapids, Iowa, Forenede Stater, 52403
- Iowa Cancer Care, PLC
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Cedar Rapids, Iowa, Forenede Stater, 52403
- Iowa Oncology Associates
-
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Maryland
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Columbia, Maryland, Forenede Stater, 21044
- Central Maryland Oncology Center
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Towson, Maryland, Forenede Stater, 21204
- Central Maryland Oncology Group
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Massachusetts
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Franklin, Massachusetts, Forenede Stater, 02038
- Impath Predictive Oncology
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Minnesota
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Minneapolis, Minnesota, Forenede Stater, 55404
- Minnesota Oncology Hematology, Pa
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St. Paul, Minnesota, Forenede Stater, 55102
- Minnesota Oncology Hematology, Pa
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Missouri
-
Columbia, Missouri, Forenede Stater, 65201
- Missouri Cancer Associates
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Kansas City, Missouri, Forenede Stater, 64111
- Kansas City Oncology and Hematology Group
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St. Louis, Missouri, Forenede Stater, 63141
- The Center for Cancer Care & Research
-
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Montana
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Billings, Montana, Forenede Stater, 59101
- Hematology Oncology Centers of the Northern Rockies
-
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New Mexico
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Santa Fe, New Mexico, Forenede Stater, 87501
- New Mexico Cancer Center Associates
-
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New York
-
Albany, New York, Forenede Stater, 12208
- New York Oncology Hematology, PC
-
Albany, New York, Forenede Stater, 12208
- New York Oncology Hematology
-
Brooklyn, New York, Forenede Stater, 11235
- HemOnCare, PC
-
East Setauket, New York, Forenede Stater, 11733
- North Shore Hematology/Oncology Associates, P.C.
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Great Neck, New York, Forenede Stater, 11023
- Cancer Research of Long Island
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Rochester, New York, Forenede Stater, 14623
- Interlakes Oncology & Hematology, P.C.
-
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North Carolina
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Asheville, North Carolina, Forenede Stater, 28801
- Asheville Hematology & Oncology Associates, PA
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Cary, North Carolina, Forenede Stater, 27511
- Raleigh Hematology Oncology Clini
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Durham, North Carolina, Forenede Stater, 27704
- Regional Hamatology Oncology Associates
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Hickory, North Carolina, Forenede Stater, 28602
- Northeastern Carolina Hematology & Oncology, PA
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Raleigh, North Carolina, Forenede Stater, 27607
- Raleigh Hematology Oncology Clinic
-
Raleigh, North Carolina, Forenede Stater, 27609
- Raleigh Hematology Oncology Clinic
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Winston-Salem, North Carolina, Forenede Stater, 27103
- Piedmont Hematology Onccology Associates, P.A.
-
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Ohio
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Kettering, Ohio, Forenede Stater, 45409
- Dayton Oncology/Hematology, PA
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Oklahoma
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Oklahoma City, Oklahoma, Forenede Stater, 73112
- Cancer Care Associates - Baptist Campus
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Tulsa, Oklahoma, Forenede Stater, 74136-1902
- Cancer Care Associates
-
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Oregon
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Eugene, Oregon, Forenede Stater, 97401
- Willamette Valley Cancer Center
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Pennsylvania
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Dunmore, Pennsylvania, Forenede Stater, 18512
- Hematology & Oncolgy Assoc of NE PA
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Kingston, Pennsylvania, Forenede Stater, 18704
- Medical Oncology Associates of Wymoning Valley, PC
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Philadelphia, Pennsylvania, Forenede Stater, 19107
- Thomas Jefferson University Hospital
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Philadelphia, Pennsylvania, Forenede Stater, 19140
- Temple Cancer Center
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Pittsburgh, Pennsylvania, Forenede Stater, 15215
- Oncology-Hematology Associates
-
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South Carolina
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Greenville, South Carolina, Forenede Stater, 29615
- Cancer Centers of the Carolinas
-
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Tennessee
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Memphis, Tennessee, Forenede Stater, 38104
- University of Tennessee Cancer Institute
-
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Texas
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Abilene, Texas, Forenede Stater, 79601-2301
- Texas Oncology, PA
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Arlington, Texas, Forenede Stater, 76012
- Texas Oncology, P.A
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Austin, Texas, Forenede Stater, 78745
- South Austin Cancer Center
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Beaumont, Texas, Forenede Stater, 77702-1449
- Mamie McFadden Ward Cancer Center
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Bedford, Texas, Forenede Stater, 76022
- Texas Oncology, P.A.
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Dallas, Texas, Forenede Stater, 75246
- Texas Oncology, PA
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Dallas, Texas, Forenede Stater, 75204
- US Oncology Research
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Dallas, Texas, Forenede Stater, 75230-2510
- Texas Cancer Center at Medical City
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Dallas, Texas, Forenede Stater, 75231
- Texas Onclology, PA
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Dallas, Texas, Forenede Stater, 75237
- The Texas Cancer Center - Dallas Southwest
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Denison, Texas, Forenede Stater, 75020-2088
- Texoma Cancer Center
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Fort Worth, Texas, Forenede Stater, 76104
- Texas Oncology, PA
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Fredicksburg, Texas, Forenede Stater, 78624
- San Antonio Tumor and Blood Clinic
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Ft. Worth, Texas, Forenede Stater, 76104
- Texas Cancer Center
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Garland, Texas, Forenede Stater, 75042-5788
- Texas Oncology, PA
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Houston, Texas, Forenede Stater, 77024
- Texas Oncology, PA
-
Houston, Texas, Forenede Stater, 77029
- Texas Oncology, PA
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Houston, Texas, Forenede Stater, 77030
- Texas Oncology, PA
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Houston, Texas, Forenede Stater, 77074-1811
- Texas Oncology, PA
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Irving, Texas, Forenede Stater, 75061
- Texas Oncology, PA
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Lewisville, Texas, Forenede Stater, 75067
- Lake Vista Cancer Center
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Mesquite, Texas, Forenede Stater, 75150
- Texas Cancer Center of Mesquite
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Midland, Texas, Forenede Stater, 79701-5946
- Allison Cancer Center
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Odessa, Texas, Forenede Stater, 79761
- West Texas Cancer Center
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San Antonio, Texas, Forenede Stater
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San Antonio, Texas, Forenede Stater, 78217
- an Antonio Tumor and Blood Clinic
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San Antonio, Texas, Forenede Stater, 78229
- Hematology Oncology Associates of South Texas
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Tyler, Texas, Forenede Stater, 75702
- Tyler Cancer Center
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Waco, Texas, Forenede Stater, 76712
- Waco Cancer Care & Research Center
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Webster, Texas, Forenede Stater, 77589
- Deke Slayton Cancer Center
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Wichita Falls, Texas, Forenede Stater, 76310
- Texoma Cancer Center
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Utah
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Salt Lake City, Utah, Forenede Stater, 84106
- Utah Cancer Specialists
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Virginia
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Fairfax, Virginia, Forenede Stater, 22031
- Fairfax Northern Virginia Hematology-Oncology, PC
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Newport News, Virginia, Forenede Stater, 23606
- Virginia Oncology Associates
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Norfolk, Virginia, Forenede Stater, 23502
- Virginia Oncology Associates
-
Salem, Virginia, Forenede Stater, 24153
- Oncology & Hematology Associates of South West Virginia, Inc.
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Washington
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Edmonds, Washington, Forenede Stater, 98026
- Puget Sound Cancer Centers
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Puyallup, Washington, Forenede Stater, 98372
- Ranier Oncology Professional Services
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Seattle, Washington, Forenede Stater, 98133
- Washington Cancer Center, P.C.Puget Sound Cancer Cente
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Spokane, Washington, Forenede Stater, 99218
- Cancer Care Northwest
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Tacoma, Washington, Forenede Stater, 98405
- MultiCare Health System
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Vancouver, Washington, Forenede Stater, 98684
- Northwest Cancer Specialists, PC
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Wisconsin
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Madison, Wisconsin, Forenede Stater, 53792
- University of Wisconsin Comprehensive Cancer Center
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
- Barn
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Beskrivelse
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Dobbelt
Samarbejdspartnere og efterforskere
Sponsor
Samarbejdspartnere
Datoer for undersøgelser
Studer store datoer
Studiestart
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Skøn)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Skøn)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
- Luftvejssygdomme
- Neoplasmer
- Lungesygdomme
- Neoplasmer efter sted
- Neoplasmer i luftvejene
- Thoracale neoplasmer
- Karcinom, bronkogent
- Bronkiale neoplasmer
- Lungeneoplasmer
- Karcinom, ikke-småcellet lunge
- Lægemidlers fysiologiske virkninger
- Molekylære mekanismer for farmakologisk virkning
- Agenter fra det perifere nervesystem
- Enzymhæmmere
- Analgetika
- Sensoriske systemagenter
- Anti-inflammatoriske midler, ikke-steroide
- Analgetika, ikke-narkotisk
- Anti-inflammatoriske midler
- Antirheumatiske midler
- Cyclooxygenase-hæmmere
- Antineoplastiske midler
- Beskyttelsesagenter
- Antikarcinogene midler
- Sulindac sulfon
Andre undersøgelses-id-numre
- 028
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .
Kliniske forsøg med Ikke-småcellet lungekræft
-
AHS Cancer Control AlbertaCross Cancer InstituteAfsluttetOmfattende Stage Small Cel Lung CancerCanada
-
Universitaire Ziekenhuizen KU LeuvenUkendtLymfom | Hodgkin lymfom | Non-Hodgkin lymfom (follikulært, diffust B-cel lymfom, PTLD og Mantle Cel lymfom)Belgien
Kliniske forsøg med Exisulind
-
Mayo ClinicOSI PharmaceuticalsAfsluttetProstatiske neoplasmerForenede Stater
-
National Cancer Institute (NCI)Afsluttet
-
Astellas Pharma IncOSI PharmaceuticalsAfsluttet
-
Mayo ClinicNational Cancer Institute (NCI)Afsluttet
-
University of UtahNational Cancer Institute (NCI)Trukket tilbageKolorektal cancer | Tyndtarmskræft
-
M.D. Anderson Cancer CenterCell PathwaysAfsluttetBrystneoplasmer | Metastaser, NeoplasmaForenede Stater
-
Eastern Cooperative Oncology GroupNational Cancer Institute (NCI)AfsluttetLungekræftForenede Stater, Australien, Puerto Rico, Sydafrika
-
Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI)AfsluttetLungekræftForenede Stater, Canada, Puerto Rico
-
Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI)AfsluttetProstatakræftForenede Stater, Canada, Puerto Rico
-
University of WashingtonOSI PharmaceuticalsAfsluttetProstatakræftForenede Stater