Denne side blev automatisk oversat, og nøjagtigheden af oversættelsen er ikke garanteret. Der henvises til engelsk version for en kildetekst.

DN-101 i kombination med docetaxel i androgen-uafhængig prostatacancer (AIPC) (AIPC-undersøgelse af calcitriolforstærkende taxotere [ASCENT-2])

2. november 2007 opdateret af: Novacea

Et fase 3, randomiseret, åbent studie, der evaluerer DN-101 i kombination med docetaxel i androgen-uafhængig prostatacancer (AIPC) (ASCENT-2)

Det primære formål med denne undersøgelse er:

At evaluere effekten af DN-101 i kombination med docetaxel (ASCENT regime) på overlevelse ved metastatisk androgen-uafhængig prostatacancer

De sekundære mål for denne undersøgelse er:

For at bestemme effekten af ASCENT-regimet på frekvensen af tromboemboliske hændelser (blodpropper)
For at bestemme effekten af ASCENT-kuren på forebyggelse af skeletrelaterede hændelser (frakturer)
En separat delundersøgelse vil blive udført på udvalgte undersøgelsessteder i Nordamerika for at bestemme populationens PK af DN-101.

Studieoversigt

Status

Afsluttet

Betingelser

Prostatakræft

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Forventet)

1200

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Canada
- Alberta
  - Calgary, Alberta, Canada, T2N4N2
    - Tom Baker Cancer Center-Medical Oncology
  - Edmonton, Alberta, Canada, T6G 1Z2
    - Cross Cancer Institute
- British Columbia
  - Kelowna, British Columbia, Canada, V1Y 5L3
    - BCCA-Centre for the Southern Interior
  - Vancouver, British Columbia, Canada, V5Z4E6
    - BCCA-Vancouver
  - Victoria, British Columbia, Canada, V8R 6V5
    - British Columbia Cancer Agency - Vancouver Island Centre
- Manitoba
  - Winnipeg, Manitoba, Canada, R3E0V9
    - Cancer Care Manitoba
- New Brunswick
  - Moncton, New Brunswick, Canada, E1C 6Z8
    - The Moncton Hospital (SERHA)
  - Moncton, New Brunswick, Canada, EIC8X3
    - Dr. Leon Richard Oncology Center
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V7
    - Centre for Clinical Research Cancer Care Program
- Ontario
  - Hamilton, Ontario, Canada, L8V 5C2
    - Jaravinski Cancer Centre Hamilton Health Services
  - Kingston, Ontario, Canada, K7L 5P9
    - Cancer Centre of Southeastern Ontario
  - London, Ontario, Canada, N6A 4L6
    - London Regional Cancer Program
  - Ottawa, Ontario, Canada, K1H 8L6
    - The Ottawa Hospital Regional Cancer Centre
  - Sudbury, Ontario, Canada, P3E 5J1
    - Regional Cancer Program de l'Hopital Regional de Sudbury
  - Toronto, Ontario, Canada, M4N 3M5
    - Toronto Sunnybrook Regional Cancer Centre
  - Windsor, Ontario, Canada, N8W 2X3
    - Windsor Regional Cancer Centre
- Quebec
  - Montreal, Quebec, Canada, H2W 1S6
    - McGill University
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7N 4H4
    - Saskatoon Cancer Centre
Forenede Stater
- Alabama
  - Birmingham, Alabama, Forenede Stater, 35223
    - Birmingham Hematology & Oncology Associates, LLC
  - Muscle Shoals, Alabama, Forenede Stater, 35661
    - Northwest Alabama Cancer Center
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Clinical Research Center
- Arizona
  - Phoenix, Arizona, Forenede Stater, 85012
    - Hematology Associates - AOA
  - Scottsdale, Arizona, Forenede Stater, 85260
    - Premiere Oncology of Arizona
  - Sedona, Arizona, Forenede Stater, 86336
    - Northern Arizona Hematology & Oncology Associates, AOA
  - Tucson, Arizona, Forenede Stater, 85723
    - Southern Arizona VA Healthcare System
  - Tucson, Arizona, Forenede Stater, 85724
    - U of Arizona / Arizona Cancer Center
- Arkansas
  - Hot Springs, Arkansas, Forenede Stater, 71913
    - Genesis Cancer Center
- California
  - Beverly Hills, California, Forenede Stater, 90211-1850
    - Tower Cancer Research Foundation
  - Long Beach, California, Forenede Stater, 90813
    - Pacific Shores Medical Group
  - Los Angeles, California, Forenede Stater, 90025
    - The Angeles Clinic and Research Institute, Inc.
  - Los Angeles, California, Forenede Stater, 90095-1738
    - UCLA Department of Urology
  - Martinez, California, Forenede Stater, 94553
    - Veterans Affairs Northern California Health Care System
  - Modesto, California, Forenede Stater, 95355
    - Sutter Gould Medical Foundation
  - Monterey, California, Forenede Stater, 93940
    - Monterey Bay Oncology
  - Palm Springs, California, Forenede Stater, 92262
    - Comprehensive Cancer Center at
  - Sacramento, California, Forenede Stater, 95816
    - Sutter Cancer Center
  - Sacramento, California, Forenede Stater, 95817
    - UCD Cancer Center-Clinical Trials
  - San Diego, California, Forenede Stater, 92123
    - Sharp Memorial Hospital
  - San Francisco, California, Forenede Stater, 94115
    - California Pacific Medical Center
  - Stanford, California, Forenede Stater, 94305
    - Stanford University
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Rocky Mountain Cancer Centers
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20007
    - Georgetown University Lombardi Cancer Center
- Florida
  - 14529 Cortez Blvd., Florida, Forenede Stater, 34613
    - Pasco Hernando Oncology Associates, P.A.
  - Deerfield Beach, Florida, Forenede Stater, 33064
    - North Broward Medical Center
  - Fort Myers, Florida, Forenede Stater, 33901
    - Florida Cancer Specialists
  - Ft. Lauderdale, Florida, Forenede Stater, 33308
    - Broward Oncology Associates
  - Ft. Lauderdale, Florida, Forenede Stater, 33308
    - Michael and Dianne Bienes Comprehensive Cancer Center
  - Gainesville, Florida, Forenede Stater, 32605
    - Gainesville Hematology Oncology Associates
  - Gainesville, Florida, Forenede Stater, 32611
    - University of Florida Shands Cancer Center
  - Jacksonville, Florida, Forenede Stater, 32256
    - Integrated Community Oncology Network
  - Miami, Florida, Forenede Stater, 33136
    - Sylvester Comprehensive Cancer Center, U of Miami
  - N. Miami Beach, Florida, Forenede Stater, 33179
    - Innovative Medical Research of South Florida Inc.
  - New Port Richey, Florida, Forenede Stater, 34655
    - Florida Cancer Institute
  - New Port Richey, Florida, Forenede Stater, 34652
    - Pasco Hernando Oncology Associates P.A.
  - Ocala, Florida, Forenede Stater, 34474
    - Ocala Oncology Center
  - Ocoee, Florida, Forenede Stater, 34761
    - Cancer Centers of Florida, P.A.
  - Trinity, Florida, Forenede Stater, 34655
    - AYS Urology
- Georgia
  - Albany, Georgia, Forenede Stater, 31701
    - Phoebe Cancer Center
  - Athens, Georgia, Forenede Stater, 30607
    - Northeast Georgia Cancer Care, LLC
  - Atlanta, Georgia, Forenede Stater, 30342
    - Atlanta Cancer Care
  - Atlanta, Georgia, Forenede Stater, 30309
    - Peachtree Hematology-Oncology Consultants, PC
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast GA Medical Center
  - Tucker, Georgia, Forenede Stater, 30084
    - Georgia Cancer Specialist
  - Valdosta, Georgia, Forenede Stater, 31602
    - South Georgia Medical Center
- Illinois
  - Chicago, Illinois, Forenede Stater, 60611
    - Hematology Oncology Associates of Illinois
  - Chicago, Illinois, Forenede Stater, 60640
    - Midwest Prostate & Urology Health Center
  - Niles, Illinois, Forenede Stater, 60714
    - Cancer Care & Hematology Specialists of Chicagoland
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Oncology Specialists
  - Rockford, Illinois, Forenede Stater, 61104
    - Swedish American Regional Cancer Center
  - Skokie, Illinois, Forenede Stater, 60077
    - Hematology Oncology Associates of Illinois, L.L.C
- Indiana
  - Indianapolis, Indiana, Forenede Stater, 46227
    - Central Indiana Cancer Centers
  - Muncie, Indiana, Forenede Stater, 47303
    - Medical Consultants, PC c/o Ball Cancer Center
  - South Bend, Indiana, Forenede Stater, 46601
    - Northern Indiana Cancer Research Consortium
  - Terre Haute, Indiana, Forenede Stater, 47802
    - Hope Center
  - Vincennes, Indiana, Forenede Stater, 47591
    - Medical Center of Vincennes
- Iowa
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Iowa Cancer Care
  - Mason City, Iowa, Forenede Stater, 50401
    - Mercy Medical Center, North Iowa
  - Sioux City, Iowa, Forenede Stater, 51101
    - Siouxland Hematology-Oncology Associates
- Kansas
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Medical Center
- Louisiana
  - Alexandria, Louisiana, Forenede Stater, 71301
    - Hematology Oncology Life Center
- Maine
  - Scarborough, Maine, Forenede Stater, 04074
    - Maine Center for Cancer Medicine & Blood Disorders
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21229
    - St. Agnes Health System
  - Columbia, Maryland, Forenede Stater, 21044
    - Maryland Oncology Hematology, P.A.
  - Frederick, Maryland, Forenede Stater, 21701
    - Frederick Memorial Hospital
- Michigan
  - Detroit, Michigan, Forenede Stater, 48202
    - Henry Ford Health System
- Minnesota
  - Minneapolis, Minnesota, Forenede Stater, 55404
    - Minnesota Oncology Hematology, P.A.
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - MN Cooperative Group Outreach Prg.
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Institute
  - St. Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Institute
- Missouri
  - Columbia, Missouri, Forenede Stater, 65201
    - Missouri Cancer Associates
  - Columbia, Missouri, Forenede Stater, 65203
    - University of Missouri, Ellis Fischel Cancer Center
  - St. Joseph, Missouri, Forenede Stater, 64507
    - St. Joseph Oncology, Inc.
- Nebraska
  - Lincoln, Nebraska, Forenede Stater, 68506
    - Nebraska Hematology-Oncology, PC
  - Omaha, Nebraska, Forenede Stater, 68144
    - Nebraska Methodist Hospital - Oncology Research Dept
  - Scottsbluff, Nebraska, Forenede Stater, 69361
    - Horizon's West Medical Group
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89109
    - Comprehensive Cancer Centers of Nevada
  - Las Vegas, Nevada, Forenede Stater, 89135
    - Nevada Cancer Institute
- New Jersey
  - Newark, New Jersey, Forenede Stater, 07101
    - UMDNJ-Newark
  - Paramus, New Jersey, Forenede Stater, 07652
    - The Valley Hospital
  - Summit, New Jersey, Forenede Stater, 07901
    - Overlook Oncology Center
- New Mexico
  - Sante Fe, New Mexico, Forenede Stater, 87505
    - New Mexico Cancer Care Associates
- New York
  - Brooklyn, New York, Forenede Stater, 11203
    - SUNY Downstate Medical Center
  - New City, New York, Forenede Stater, 10956
    - Hematology Oncology Associates of
  - New York, New York, Forenede Stater, 10021
    - Memorial Sloan-Kett
  - Rochester, New York, Forenede Stater, 14642
    - University of Rochester Medical Center
  - Rochester, New York, Forenede Stater, 14623
    - Interlakes Foundation Inc.
  - Staten Island, New York, Forenede Stater, 10304
    - Staten Island Urological Research, PC
- North Carolina
  - Cary, North Carolina, Forenede Stater, 27511
    - Raleigh Hematology Oncology Associates
  - Fayetteville, North Carolina, Forenede Stater, 28304
    - Carolina Cancer Management, Inc.
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Piedmont Hematology Oncology Associates, PLLC
- North Dakota
  - Fargo, North Dakota, Forenede Stater, 58103
    - Dakota Cancer Institute
- Ohio
  - Canton, Ohio, Forenede Stater, 44718
    - Gabrail Cancer Center
  - Canton, Ohio, Forenede Stater, 44710
    - Aultman Hospital
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Oncology Hematology Care, Inc.
  - Cleveland, Ohio, Forenede Stater, 44195
    - The Cleveland Clinic Foundation
  - Columbus, Ohio, Forenede Stater, 43213
    - Mid Ohio Oncology/Hematology, Inc.
  - Kettering, Ohio, Forenede Stater, 45409
    - Dayton Oncology & Hematology, P.A.
- Oklahoma
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - University of Oklahoma
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - Cancer Care Associates
  - Tulsa, Oklahoma, Forenede Stater, 74136
    - Cancer Care Associates
- Oregon
  - Eugene, Oregon, Forenede Stater, 97401-8122
    - Willamette Valley Cancer Center
- Pennsylvania
  - Drexel Hill, Pennsylvania, Forenede Stater, 19026
    - Consultants in Medical Oncology & Hematology
  - Dunmore, Pennsylvania, Forenede Stater, 18512
    - Hematology & Oncology Associates of Northeastern PA
  - Kingston, Pennsylvania, Forenede Stater, 18704
    - Medical Oncology Associates of Wyoming Valley, PC
  - Langhorne, Pennsylvania, Forenede Stater, 19047
    - St. Mary Medical Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19114
    - Greater Philadelphia Cancer
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - Univeristy of Pittsburgh Cancer Institute
  - Pottsville, Pennsylvania, Forenede Stater, 17901
    - Pottsville Cancer Care
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Guthrie Clinic
- South Carolina
  - Charleston, South Carolina, Forenede Stater, 29425
    - Medical University of South Carolina
  - Charleston, South Carolina, Forenede Stater, 29406
    - Charleston Cancer Center
  - Charleston, South Carolina, Forenede Stater, 29403
    - Charleston Hematology Oncology PA
  - Greenville, South Carolina, Forenede Stater, 29615
    - Cancer Centers of the Carolina
  - Hilton Head Island, South Carolina, Forenede Stater, 29926
    - South Carolina Cancer Specialists
- Tennessee
  - Chattanooga, Tennessee, Forenede Stater, TN
    - Chattanooga Oncology & Hematology Assoc.
  - Germantown, Tennessee, Forenede Stater, 38138
    - The Jones Clinic
  - Nashville, Tennessee, Forenede Stater, 37203
    - Sarah Cannon Research Institute
- Texas
  - Abilene, Texas, Forenede Stater, 79606-5208
    - Texas Cancer Center-Abilene
  - Amarillo, Texas, Forenede Stater, 79106
    - Texas Oncology, PA
  - Arlington, Texas, Forenede Stater, 76014
    - Texas Cancer Center
  - Arlington, Texas, Forenede Stater, 76017
    - Urology Associates of North Texas (UANT)
  - Austin, Texas, Forenede Stater, 78731
    - Texas Oncology Cancer Center
  - Beaumont, Texas, Forenede Stater, 77702-1449
    - MamieMcFaddin Ward Cancer Center
  - Dallas, Texas, Forenede Stater, 75231-4400
    - Texas Oncology, P.A.
  - Dallas, Texas, Forenede Stater, 75237
    - The Texas Cancer Center
  - Dallas, Texas, Forenede Stater, 75230
    - Center for Oncology Research and Treatment, PA
  - Dallas, Texas, Forenede Stater, 75230-2510
    - Texas Cancer Center ar Medical City
  - El Paso, Texas, Forenede Stater, 79915
    - El Paso Cancer Treatment Center-East
  - Fort Worth, Texas, Forenede Stater, 76104
    - Texas Oncology, P.A.
  - Fort Worth, Texas, Forenede Stater, 76104
    - The Center for Cancer & Blood Disorders
  - Garland, Texas, Forenede Stater, 75042-5788
    - Texas Oncology, P.A.
  - Houston, Texas, Forenede Stater, 77024
    - Texas Oncology, P.A.
  - Lewisville, Texas, Forenede Stater, 75067
    - Lake Vista Cancer Center
  - Longview, Texas, Forenede Stater, 75601
    - Texas Oncology, P.A.
  - Lubbock, Texas, Forenede Stater, 79415
    - Southwest Cancer Treatment And Research Center
  - McAllen, Texas, Forenede Stater, 78503
    - South Texas Cancer Center - McAllen
  - Mesquite, Texas, Forenede Stater, 75150
    - Texas Cancer Center of Mesquite
  - Midland, Texas, Forenede Stater, 79701-5946
    - Allison Cancer Center
  - New Braunfels, Texas, Forenede Stater, 78131
    - Cancer Care Network of South Texas, HOAST
  - Odessa, Texas, Forenede Stater, 79761
    - West Texas Cancer Center
  - Paris, Texas, Forenede Stater, 75460-5004
    - Paris Regional Cancer Center
  - San Antonio, Texas, Forenede Stater, 78229
    - South Texas Oncology and Hematology, PA
  - San Antonio, Texas, Forenede Stater, 78233
    - InVisions Consultants LLC
  - Sherman, Texas, Forenede Stater, 75090-0504
    - Texas Cancer Center- Sherman
  - Sugar Land, Texas, Forenede Stater, 77479
    - Texas Oncology Cancer Center-Sugar Land
  - Waco, Texas, Forenede Stater, 76712
    - Texas Oncology Cancer Care and Research Center
  - Waco, Texas, Forenede Stater, 76022
    - Texas Oncology
- Virginia
  - Fairfax, Virginia, Forenede Stater, 22031
    - Fairfax Northern Virginia Hematology Oncology, PC
  - Norfolk, Virginia, Forenede Stater, 23502
    - Virginia Oncology Associates
  - Salem, Virginia, Forenede Stater, 24153
    - Oncology & Hematology Associates of Southwest Virginia, Inc.
- Washington
  - Burien, Washington, Forenede Stater, 98166
    - Highline Medical Oncology
  - Edmonds, Washington, Forenede Stater, 98026
    - Puget Sound Cancer Centers
  - Seattle, Washington, Forenede Stater, 98109
    - University of Washington
  - Seattle, Washington, Forenede Stater, 98133
    - Puget Sound Cancer Centers
  - Vancouver, Washington, Forenede Stater, 98684
    - Northwest Cancer Specialists, P.C.
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Medical Center
  - Yakima, Washington, Forenede Stater, 98902
    - Yakima Valley Memorial Hospital/North Star Lodge
- Wisconsin
  - Milwaukee, Wisconsin, Forenede Stater, 53226
    - Medical College of Wisconsin
Puerto Rico
- - San Juan, Puerto Rico, 00921
    - San Juan VA Medical Center, Reseach Dept
Rumænien
- - Arad, Rumænien, 310175
    - Cabinetul de Urologie
  - Brasov, Rumænien, 500366
    - Policlinica de Diagnostic Rapid
  - Bucuresti, Rumænien
    - Institutul Oncologic Bucuresti
  - Cluj Napoca, Rumænien, 400046
    - Euro S.R.L.
  - Constanta, Rumænien, 900635
    - ProVita 2000
Slovakiet
- - Banska Bystrica, Slovakiet, 97517
    - Theaching Hospital of F.D. Roosevelt
  - Martin, Slovakiet, 03659
    - Faculty Hospital Martin
  - Presov, Slovakiet
    - Faculty Hospital of J. A. Reiman
Tidligere Serbien og Montenegro
- - Belgrade, Tidligere Serbien og Montenegro, 18000
    - Clinical Center Niš - Clinic of Urology
Tjekkiet
- - Prague, Tjekkiet, 180 81
    - Institute of Radiation Oncology of Teaching Hospital Na Bulovce
  - Prague, Tjekkiet
    - Department of Radiation and Oncology of Teaching Hospital Motol
  - Prague, Tjekkiet
    - Teaching Hospital Královské Vinohrady
Tyskland
- - Augsburg, Tyskland, 86150
    - Gemeinschaftspraxis für Hämatologie & Onkologie
  - Bad Schwartau, Tyskland, 23611
    - Facharzt f. Urologie
  - Bautzen, Tyskland, 02625
    - Urologische Praxis
  - Berlin, Tyskland, 10117
    - Universitätsmedizin Charité
  - Berlin, Tyskland, 10967
    - Klinik am Urban
  - Berlin, Tyskland, 12200
    - Universitätsmedizin Charité Campus Benjamin Franklin
  - Berlin, Tyskland
    - Urologische Praxis
  - Braunschweig, Tyskland, 38126
    - Städtisches Klinikum Braunschweig
  - Cottbus, Tyskland, 03046
    - Facharzt f. Urologie
  - Dresden, Tyskland, 01307
    - Urologische Klinik
  - Düsseldorf, Tyskland, 40225
    - Universitäsklinikum Düsseldorf
  - Düsseldorf, Tyskland, 40225
    - Urologische Klinik der Universitätsklink Düsseldorf
  - Essen, Tyskland
    - Universitätsklinikum Essen
  - Fulda, Tyskland, 36043
    - Klinikum Fulda, Urologische Klinik
  - Hagenow, Tyskland
    - Urologische Praxis
  - Hamburg, Tyskland, 22399
    - Urologische Gemeinschaftspraxis
  - Hannover, Tyskland, 30625
    - Medizinische Hochschule Hannover
  - Heidelberg, Tyskland, 69120
    - Nationales Centrum für Tumorerkrankungen
  - Homburg, Tyskland
    - Universitätsklinikum Homburg/Saar
  - Kassel, Tyskland, 34125
    - Klinikum Kassel Gmbh
  - Kirchheim/Teck, Tyskland, 73230
    - Gemeinschaftspraxis für Urologie
  - Leipzig, Tyskland
    - Gesellschaft f. klinische Studien und Urologisches Gesundheitszentrum
  - München, Tyskland, 81675
    - Oberarzt d. Urolog. Abteilung
  - Münster, Tyskland, 48149
    - Obearzt der Urologischen Klinik, Universitätsklinik Münster
  - Wilhelmshaven, Tyskland, 26389
    - Praxisgemeinschaft für Onkologie und Urologie
  - Wuppertal, Tyskland, 42103
    - Gemeinschaftspraxis f. Urologie
  - Zwickau, Tyskland
    - Urologische Praxis
- 50931
  - Köln, 50931, Tyskland
    - Universitätsklinikum Köln
Ungarn
- - Budapest, Ungarn, 1071
    - IRM Center Hospital and Institutes, II.Department of Oncology
  - Budapest, Ungarn, H-1145
    - Uzsoki Hospital of the Local Authority of Budapest, Oncoradiology
  - Debrecen, Ungarn, H4032
    - University of Debrecen, Medical and Health Science Center, Department of Oncology
  - Szeged, Ungarn
    - University of Szeged, Szent-Györgyi Albert Medical and Pharmacist Science Center, Clinic of Oncotherapy

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Han

Beskrivelse

Inklusionskriterier:

Histopatologisk eller cytologisk bevist adenocarcinom i prostata
Dokumenteret metastatisk prostata adenokarcinom
Dokumenteret progression under androgen-ablationsterapi påvist ved stigende prostataspecifikt antigen (PSA) og/eller billeddannelse
Alder >= 18 år
Eastern Cooperative Oncology Group (ECOG) præstationsstatus <= 2
Tilstrækkelig hæmatologisk, nyre- og leverfunktion
Forventet levetid >= 3 måneder

Ekskluderingskriterier:

Forudgående kemoterapi, undtagen estramustin
Forudgående kemoterapi med docetaxel
Tidligere isotopbehandling (f.eks. strontium-89, samarium-153 osv.)
En eller flere kontraindikationer til brugen af kortikosteroider
Anamnese med kræftrelateret hypercalcæmi

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Ingen (Åben etiket)

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Novacea

Efterforskere

Studiestol: Howard I. Scher, MD, Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center
Studiestol: Kim N. Chi, M.D., British Columbia Cancer Agency - Vancouver Centre
Studiestol: Ronald De-Wit, M.D., Erasmus University Medical Center (Netherlands)

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. januar 2006

Studieafslutning (Faktiske)

1. november 2007

Datoer for studieregistrering

Først indsendt

14. december 2005

Først indsendt, der opfyldte QC-kriterier

5. januar 2006

Først opslået (Skøn)

9. januar 2006

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

6. november 2007

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

2. november 2007

Sidst verificeret

1. november 2007

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

011-007

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .