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Sammenligning af forskellige typer kirurgi til behandling af patienter med fase IA ikke-småcellet lungekræft

20. januar 2026 opdateret af: Alliance for Clinical Trials in Oncology

Et fase III randomiseret forsøg med lobektomi versus sublobar resektion for små (≤ 2 cm) perifer ikke-småcellet lungekræft

RATIONALE: Kileresektion eller segmentektomi kan være mindre invasive typer operationer end lobektomi for ikke-småcellet lungekræft og kan have færre bivirkninger og forbedre restitutionen. Det vides endnu ikke, om kileresektion eller segmentektomi er mere effektive end lobektomi til behandling af ikke-småcellet lungecancer i stadium IA.

FORMÅL: Dette randomiserede fase III-forsøg studerer forskellige typer operationer for at sammenligne, hvor godt de virker til at behandle patienter med fase IA ikke-småcellet lungekræft.

Studieoversigt

Status

Afsluttet

Betingelser

Lungekræft

Intervention / Behandling

Detaljeret beskrivelse

OVERSIGT: Dette er en multicenter, randomiseret undersøgelse. Patienterne stratificeres efter tumorstørrelse (< 1 cm vs. 1-1,5 cm vs. > 1,5-2,0 cm) (baseret på den maksimale dimension bestemt fra den præoperative CT-scanning), histologi (pladecellekarcinom vs adenokarcinom vs andet) og rygestatus (aldrig røget [røget < 100 cigaretter i løbet af livet] vs tidligere ryger [røget > 100 cigaretter OG holdt op for ≥ 1 år siden] vs. nuværende ryger [stop for < 1 år siden eller ryger i øjeblikket]). Patienterne randomiseres til 1 ud af 2 behandlingsarme. For mere information, se venligst afsnittet Arms.

Primært mål:

For at bestemme, om DFS efter sublobar resektion (segmentektomi eller kile) er ikke ringere end efter lobektomi hos patienter med lille perifer (≤ 2 cm) NSCLC.

Sekundære mål:

For at bestemme, om den samlede overlevelse (OS) (efter sublobar resektion) er ikke ringere end efter lobektomi.
At bestemme frekvensen af loko-regional og systemisk gentagelse (eksklusive sekundære primære) efter lobar og sublobar resektion.
For at bestemme forskellen mellem de to arme af undersøgelsen i lungefunktion som bestemt ved ekspiratoriske flowhastigheder målt 6 måneder efter operationen.
Billeddiagnostisk delstudie: At udforske forholdet mellem karakteristika ved den primære lungecancer, som afsløret af præoperativ CT- og PET-billeddannelse, og resultater; en bestemmelse af den falsk-negative rate af den præoperative PET-scanning til identifikation af involverede hilarand mediastinale lymfeknuder; og en vurdering af nytten af årlig opfølgende CT-billeddannelse efter kirurgisk resektion af lille stadium IA NSCLC.

Efter afsluttet undersøgelsesbehandling følges patienterne hver 6. måned i 2 år og derefter årligt i 5 år.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

701

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Australien
- Victoria
  - Fitzroy, Victoria, Australien, 3065
    - Saint Vincent's Hospital
Canada
- - Québec, Canada, G1V 4G5
    - University Institute of Cardiology and Pneumology of Quebec (Laval Hospital)
- British Columbia
  - Surrey, British Columbia, Canada, V3V 1Z2
    - Surrey Memorial Hospital
- New Brunswick
  - Moncton, New Brunswick, Canada, E1C 6Z8
    - The Moncton Hospital
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V8
    - QEII Health Sciences Centre/Capital District Health Authority
- Ontario
  - Hamilton, Ontario, Canada, L8N 4A6
    - Saint Joseph's Healthcare Charlton Campus
  - London, Ontario, Canada, N6A 4L6
    - London Regional Cancer Program
  - Ottawa, Ontario, Canada, K1H 8L6
    - Ottawa Hospital and Cancer Center-General Campus
  - Toronto, Ontario, Canada, M5G 2M9
    - University Health Network-Princess Margaret Hospital
  - Toronto, Ontario, Canada, M6R 1B5
    - Saint Joseph's Health Centre
- Quebec
  - Montreal, Quebec, Canada, H2L 4M1
    - CHUM - Hopital Notre-Dame
  - Montreal, Quebec, Canada, H1T 2M4
    - CIUSSSEMTL-Hopital Maisonneuve-Rosemont
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Forenede Stater
- Alabama
  - Birmingham, Alabama, Forenede Stater, 35233
    - University of Alabama at Birmingham Cancer Center
- Alaska
  - Anchorage, Alaska, Forenede Stater, 98508
    - Anchorage Associates in Radiation Medicine
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Breast Care and Surgery LLC
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Oncology and Hematology LLC
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Women's Cancer Care
  - Anchorage, Alaska, Forenede Stater, 99508
    - Anchorage Oncology Centre
  - Anchorage, Alaska, Forenede Stater, 99508
    - Katmai Oncology Group
  - Anchorage, Alaska, Forenede Stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forenede Stater, 99504
    - Anchorage Radiation Therapy Center
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Regional Hospital
- Arizona
  - Scottsdale, Arizona, Forenede Stater, 85259
    - Mayo Clinic in Arizona
  - Tucson, Arizona, Forenede Stater, 85724
    - The University of Arizona Medical Center-University Campus
- Arkansas
  - Hot Springs, Arkansas, Forenede Stater, 71913
    - Mercy Cancer Center-Hot Springs
  - Little Rock, Arkansas, Forenede Stater, 72205
    - University of Arkansas for Medical Sciences
  - Rogers, Arkansas, Forenede Stater, 72758
    - Highlands Oncology Group-Rogers
- California
  - Burbank, California, Forenede Stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Carmichael, California, Forenede Stater, 95608
    - Mercy San Juan Medical Center
  - Fullerton, California, Forenede Stater, 92835
    - Saint Jude Medical Center
  - Loma Linda, California, Forenede Stater, 92354
    - Loma Linda University Medical Center
  - Loma Linda, California, Forenede Stater, 92357
    - Veterans Affairs Loma Linda Healthcare System
  - Long Beach, California, Forenede Stater, 90822
    - Veterans Administration Long Beach Medical Center
  - Orange, California, Forenede Stater, 92868
    - UC Irvine Health/Chao Family Comprehensive Cancer Center
  - Riverside, California, Forenede Stater, 92505
    - Kaiser Permanente-Riverside
  - Sacramento, California, Forenede Stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - San Diego, California, Forenede Stater, 92103
    - University Of California San Diego
- Colorado
  - Aurora, Colorado, Forenede Stater, 80045
    - University of Colorado Cancer Center - Anschutz Cancer Pavilion
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - Rocky Mountain Cancer Centers-Penrose
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Memorial Hospital Colorado Springs
  - Denver, Colorado, Forenede Stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forenede Stater, 80217-3364
    - University of Colorado
  - Durango, Colorado, Forenede Stater, 81301
    - Mercy Medical Center
  - Durango, Colorado, Forenede Stater, 81301
    - Southwest Oncology PC
  - Golden, Colorado, Forenede Stater, 80401
    - Mountain Blue Cancer Care Center
  - Lakewood, Colorado, Forenede Stater, 80228
    - Saint Anthony Hospital
  - Lakewood, Colorado, Forenede Stater, 80228
    - Rocky Mountain Cancer Centers-Lakewood
  - Littleton, Colorado, Forenede Stater, 80122
    - Littleton Adventist Hospital
  - Longmont, Colorado, Forenede Stater, 80501
    - Longmont United Hospital
  - Longmont, Colorado, Forenede Stater, 80501
    - Rocky Mountain Cancer Centers-Longmont
  - Parker, Colorado, Forenede Stater, 80138
    - Parker Adventist Hospital
  - Parker, Colorado, Forenede Stater, 80138
    - Rocky Mountain Cancer Centers-Parker
  - Pueblo, Colorado, Forenede Stater, 81004
    - Saint Mary Corwin Medical Center
  - Pueblo, Colorado, Forenede Stater, 81008
    - Rocky Mountain Cancer Centers - Pueblo
  - Thornton, Colorado, Forenede Stater, 80260
    - Rocky Mountain Cancer Centers-Thornton
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06606
    - Saint Vincent's Medical Center
  - Hartford, Connecticut, Forenede Stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - Stamford, Connecticut, Forenede Stater, 06904
    - Stamford Hospital/Bennett Cancer Center
- Delaware
  - Lewes, Delaware, Forenede Stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forenede Stater, 19713
    - Helen F Graham Cancer Center
  - Newark, Delaware, Forenede Stater, 19713
    - Delaware Clinical and Laboratory Physicians PA
  - Newark, Delaware, Forenede Stater, 19713
    - Medical Oncology Hematology Consultants PA
  - Newark, Delaware, Forenede Stater, 19718
    - Christiana Care Health System-Christiana Hospital
  - Newark, Delaware, Forenede Stater, 19713
    - Christiana Gynecologic Oncology LLC
  - Newark, Delaware, Forenede Stater, 19713
    - Regional Hematology and Oncology PA
  - Rehoboth Beach, Delaware, Forenede Stater, 19971
    - Beebe Health Campus
  - Seaford, Delaware, Forenede Stater, 19973
    - Nanticoke Memorial Hospital
  - Wilmington, Delaware, Forenede Stater, 19801
    - Christiana Care Health System-Wilmington Hospital
- Florida
  - Boca Raton, Florida, Forenede Stater, 33486
    - Boca Raton Regional Hospital
  - Jacksonville, Florida, Forenede Stater, 32224-9980
    - Mayo Clinic in Florida
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forenede Stater, 30322
    - Emory University/Winship Cancer Institute
  - Decatur, Georgia, Forenede Stater, 30033
    - Atlanta VA Medical Center
  - Savannah, Georgia, Forenede Stater, 31404
    - Memorial University Medical Center
- Idaho
  - Boise, Idaho, Forenede Stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forenede Stater, 83712
    - Saint Luke's Mountain States Tumor Institute
  - Caldwell, Idaho, Forenede Stater, 83605
    - Saint Alphonsus Cancer Care Center-Caldwell
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - Kootenai Medical Center
  - Emmett, Idaho, Forenede Stater, 83617
    - Walter Knox Memorial Hospital
  - Fruitland, Idaho, Forenede Stater, 83619
    - Saint Luke's Mountain States Tumor Institute - Fruitland
  - Lewiston, Idaho, Forenede Stater, 83501
    - Saint Joseph Regional Medical Center
  - Meridian, Idaho, Forenede Stater, 83642
    - Idaho Urologic Institute-Meridian
  - Meridian, Idaho, Forenede Stater, 83642
    - Saint Luke's Mountain States Tumor Institute - Meridian
  - Nampa, Idaho, Forenede Stater, 83686
    - Saint Alphonsus Medical Center-Nampa
  - Nampa, Idaho, Forenede Stater, 83686
    - Saint Luke's Mountain States Tumor Institute - Nampa
  - Pocatello, Idaho, Forenede Stater, 83201
    - Portneuf Medical Center
  - Post Falls, Idaho, Forenede Stater, 83854
    - Kootenai Cancer Center
  - Sandpoint, Idaho, Forenede Stater, 83864
    - Kootenai Cancer Clinic
  - Twin Falls, Idaho, Forenede Stater, 83301
    - Saint Luke's Mountain States Tumor Institute-Twin Falls
- Illinois
  - Chicago, Illinois, Forenede Stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Springfield, Illinois, Forenede Stater, 62702
    - Southern Illinois University School of Medicine
  - Springfield, Illinois, Forenede Stater, 62702
    - Saint John's Hospital
- Indiana
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Indiana University/Melvin and Bren Simon Cancer Center
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Sidney and Lois Eskenazi Hospital
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Richard L. Roudebush Veterans Affairs Medical Center
  - Mishawaka, Indiana, Forenede Stater, 46544
    - Memorial Regional Cancer Center Day Road
  - South Bend, Indiana, Forenede Stater, 46601
    - Memorial Hospital of South Bend
- Iowa
  - Clive, Iowa, Forenede Stater, 50325
    - Mercy Cancer Center-West Lakes
  - Clive, Iowa, Forenede Stater, 50325
    - Medical Oncology and Hematology Associates-West Des Moines
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Alegent Health Mercy Hospital
  - Creston, Iowa, Forenede Stater, 50801
    - Greater Regional Medical Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forenede Stater, 50314
    - Medical Oncology and Hematology Associates-Laurel
  - West Des Moines, Iowa, Forenede Stater, 50266
    - Mercy Medical Center-West Lakes
- Kansas
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Cancer Center
  - Olathe, Kansas, Forenede Stater, 66061
    - Olathe Cancer Center
  - Overland Park, Kansas, Forenede Stater, 66209
    - Menorah Medical Center
  - Overland Park, Kansas, Forenede Stater, 66213
    - Saint Luke's South Hospital
  - Shawnee Mission, Kansas, Forenede Stater, 66204
    - Shawnee Mission Medical Center-KCCC
- Kentucky
  - Bardstown, Kentucky, Forenede Stater, 40004
    - Flaget Memorial Hospital
  - Corbin, Kentucky, Forenede Stater, 40701
    - Commonwealth Cancer Center-Corbin
  - Lexington, Kentucky, Forenede Stater, 40536
    - University of Kentucky/Markey Cancer Center
  - Lexington, Kentucky, Forenede Stater, 40504
    - Saint Joseph Radiation Oncology Resource Center
  - Lexington, Kentucky, Forenede Stater, 40509
    - Saint Joseph Hospital East
  - Louisville, Kentucky, Forenede Stater, 40202
    - Jewish Hospital
  - Louisville, Kentucky, Forenede Stater, 40215
    - Saints Mary and Elizabeth Hospital
  - Louisville, Kentucky, Forenede Stater, 40245
    - Jewish Hospital Medical Center Northeast
  - Shepherdsville, Kentucky, Forenede Stater, 40165
    - Jewish Hospital Medical Center South
- Louisiana
  - New Orleans, Louisiana, Forenede Stater, 70121
    - Ochsner Medical Center Jefferson
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - Anne Arundel Medical Center
  - Baltimore, Maryland, Forenede Stater, 21201
    - University of Maryland/Greenebaum Cancer Center
  - Bel Air, Maryland, Forenede Stater, 21014
    - Upper Chesapeake Medical Center
  - Elkton, Maryland, Forenede Stater, 21921
    - Union Hospital of Cecil County
  - Silver Spring, Maryland, Forenede Stater, 20910
    - Holy Cross Hospital
- Massachusetts
  - Boston, Massachusetts, Forenede Stater, 02215
    - Dana-Farber Cancer Institute
  - Boston, Massachusetts, Forenede Stater, 02115
    - Brigham and Women's Hospital
  - Boston, Massachusetts, Forenede Stater, 02118
    - Boston Medical Center
  - Boston, Massachusetts, Forenede Stater, 02114
    - Massachusetts General Hospital Cancer Center
  - Pittsfield, Massachusetts, Forenede Stater, 01201
    - Berkshire Hematology Oncology PC
  - Springfield, Massachusetts, Forenede Stater, 01107
    - D'Amour Center for Cancer Care
  - Worcester, Massachusetts, Forenede Stater, 01605
    - University of Massachusetts Memorial Health Care
- Michigan
  - Ann Arbor, Michigan, Forenede Stater, 48106-0995
    - Saint Joseph Mercy Hospital
  - Ann Arbor, Michigan, Forenede Stater, 48109
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Michigan Cancer Research Consortium NCORP
  - Brighton, Michigan, Forenede Stater, 48114
    - Saint Joseph Mercy Brighton
  - Brighton, Michigan, Forenede Stater, 48114
    - IHA Hematology Oncology Consultants-Brighton
  - Canton, Michigan, Forenede Stater, 48188
    - IHA Hematology Oncology Consultants-Canton
  - Canton, Michigan, Forenede Stater, 48188
    - Saint Joseph Mercy Canton Health Center
  - Caro, Michigan, Forenede Stater, 48723
    - Caro Cancer Center
  - Chelsea, Michigan, Forenede Stater, 48118
    - Saint Joseph Mercy Chelsea
  - Chelsea, Michigan, Forenede Stater, 48118
    - IHA Hematology Oncology Consultants-Chelsea
  - Clarkston, Michigan, Forenede Stater, 48346
    - Hematology Oncology Consultants-Clarkston
  - Clarkston, Michigan, Forenede Stater, 48346
    - Newland Medical Associates-Clarkston
  - Dearborn, Michigan, Forenede Stater, 48124
    - Beaumont Hospital-Dearborn
  - Detroit, Michigan, Forenede Stater, 48202
    - Henry Ford Hospital
  - Detroit, Michigan, Forenede Stater, 48236
    - Saint John Hospital and Medical Center
  - East China Township, Michigan, Forenede Stater, 48054
    - Great Lakes Cancer Management Specialists-Doctors Park
  - Flint, Michigan, Forenede Stater, 48502
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48532
    - Genesys Regional Medical Center-West Flint Campus
  - Flint, Michigan, Forenede Stater, 48503
    - Genesee Cancer and Blood Disease Treatment Center
  - Flint, Michigan, Forenede Stater, 48503
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forenede Stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Blanc, Michigan, Forenede Stater, 48439
    - Genesys Regional Medical Center
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Michigan Breast Specialists-Grosse Pointe Woods
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Lymphoma Clinic of Michigan
  - Jackson, Michigan, Forenede Stater, 49201
    - Allegiance Health
  - Lansing, Michigan, Forenede Stater, 48912
    - Sparrow Hospital
  - Livonia, Michigan, Forenede Stater, 48154
    - Saint Mary Mercy Hospital
  - Livonia, Michigan, Forenede Stater, 48154
    - Hope Cancer Clinic
  - Macomb, Michigan, Forenede Stater, 48044
    - Michigan Breast Specialists-Macomb Township
  - Macomb, Michigan, Forenede Stater, 48044
    - Hematology Oncology Associates East PC
  - Pontiac, Michigan, Forenede Stater, 48341
    - Saint Joseph Mercy Oakland
  - Pontiac, Michigan, Forenede Stater, 48341
    - 21st Century Oncology-Pontiac
  - Pontiac, Michigan, Forenede Stater, 48341
    - Hope Cancer Center
  - Pontiac, Michigan, Forenede Stater, 48341
    - Newland Medical Associates-Pontiac
  - Port Huron, Michigan, Forenede Stater, 48060
    - Lake Huron Medical Center
  - Rochester Hills, Michigan, Forenede Stater, 48309
    - Great Lakes Cancer Management Specialists-Rochester Hills
  - Saginaw, Michigan, Forenede Stater, 48601
    - Saint Mary's of Michigan
  - Saginaw, Michigan, Forenede Stater, 48604
    - Oncology Hematology Associates of Saginaw Valley PC
  - Sterling Heights, Michigan, Forenede Stater, 48312
    - Bhadresh Nayak MD PC-Sterling Heights
  - Warren, Michigan, Forenede Stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Warren, Michigan, Forenede Stater, 48093
    - Great Lakes Cancer Management Specialists-Macomb Professional Building
  - Warren, Michigan, Forenede Stater, 48093
    - Macomb Hematology Oncology PC
  - Warren, Michigan, Forenede Stater, 48093
    - Michigan Breast Specialists-Warren
  - West Branch, Michigan, Forenede Stater, 48661
    - Saint Mary's Oncology/Hematology Associates of West Branch
  - Ypsilanti, Michigan, Forenede Stater, 48106
    - Huron Gastroenterology PC
  - Ypsilanti, Michigan, Forenede Stater, 48197
    - IHA Hematology Oncology Consultants-Ann Arbor
- Minnesota
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic
- Missouri
  - Cape Girardeau, Missouri, Forenede Stater, 63701
    - Southeast Missouri Hospital
  - Kansas City, Missouri, Forenede Stater, 64116
    - North Kansas City Hospital
  - Kansas City, Missouri, Forenede Stater, 64111
    - Saint Luke's Hospital of Kansas City
  - Kansas City, Missouri, Forenede Stater, 64132
    - Research Medical Center
  - Kansas City, Missouri, Forenede Stater, 64108
    - Truman Medical Center
  - Kansas City, Missouri, Forenede Stater, 64118
    - Heartland Hematology and Oncology Associates Incorporated
  - Kansas City, Missouri, Forenede Stater, 64114
    - Saint Joseph Health Center
  - Lee's Summit, Missouri, Forenede Stater, 64086
    - Saint Luke's East - Lee's Summit
  - Liberty, Missouri, Forenede Stater, 64068
    - Liberty Radiation Oncology Center
  - Saint Joseph, Missouri, Forenede Stater, 64506
    - Heartland Regional Medical Center
  - Saint Joseph, Missouri, Forenede Stater, 64507
    - Saint Joseph Oncology Inc
  - St Louis, Missouri, Forenede Stater, 63136
    - Christian Hospital
  - St Louis, Missouri, Forenede Stater, 63110
    - Washington University School of Medicine
- Montana
  - Anaconda, Montana, Forenede Stater, 59711
    - Community Hospital of Anaconda
  - Billings, Montana, Forenede Stater, 59101
    - Billings Clinic Cancer Center
  - Billings, Montana, Forenede Stater, 59101
    - Saint Vincent Healthcare
  - Bozeman, Montana, Forenede Stater, 59715
    - Bozeman Deaconess Hospital
  - Butte, Montana, Forenede Stater, 59701
    - Saint James Community Hospital and Cancer Treatment Center
  - Great Falls, Montana, Forenede Stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forenede Stater, 59405
    - Benefis Healthcare- Sletten Cancer Institute
  - Great Falls, Montana, Forenede Stater, 59405
    - Big Sky Oncology
  - Helena, Montana, Forenede Stater, 59601
    - Saint Peter's Community Hospital
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Regional Medical Center
  - Missoula, Montana, Forenede Stater, 59804
    - Community Medical Hospital
  - Missoula, Montana, Forenede Stater, 59802
    - Saint Patrick Hospital - Community Hospital
- Nebraska
  - Grand Island, Nebraska, Forenede Stater, 68803
    - CHI Health Saint Francis
  - Kearney, Nebraska, Forenede Stater, 68847
    - CHI Health Good Samaritan
  - Kearney, Nebraska, Forenede Stater, 68845
    - Heartland Hematology and Oncology
  - Lincoln, Nebraska, Forenede Stater, 68510
    - Saint Elizabeth Regional Medical Center
  - Omaha, Nebraska, Forenede Stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forenede Stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forenede Stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forenede Stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Hemotology and Oncology Consultants PC
  - Papillion, Nebraska, Forenede Stater, 68046
    - Midlands Community Hospital
- New Jersey
  - Basking Ridge, New Jersey, Forenede Stater, 07920
    - Memorial Sloan Kettering Cancer Center at Basking Ridge
  - Brick, New Jersey, Forenede Stater, 08724
    - Ocean Medical Center
  - Camden, New Jersey, Forenede Stater, 08103
    - Cooper Hospital University Medical Center
  - Edison, New Jersey, Forenede Stater, 08818
    - John F Kennedy Medical Center
  - Manahawkin, New Jersey, Forenede Stater, 08050
    - Southern Ocean County Medical Center
  - Neptune City, New Jersey, Forenede Stater, 07753
    - Jersey Shore Medical Center
  - Paramus, New Jersey, Forenede Stater, 07652
    - The Valley Hospital-Luckow Pavilion
  - Red Bank, New Jersey, Forenede Stater, 07701
    - Riverview Medical Center/Booker Cancer Center
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - Valley Hospital
  - Westwood, New Jersey, Forenede Stater, 07675
    - Valley Health System-Hematology/Oncology
- New York
  - Buffalo, New York, Forenede Stater, 14263
    - Roswell Park Cancer Institute
  - Commack, New York, Forenede Stater, 11725
    - Memorial Sloan Kettering Commack
  - East Syracuse, New York, Forenede Stater, 13057
    - Hematology Oncology Associates of Central New York-East Syracuse
  - Flushing, New York, Forenede Stater, 11355
    - The New York Hospital Medical Center of Queens
  - Harrison, New York, Forenede Stater, 10604
    - Memorial Sloan-Kettering Cancer Center West Harrison
  - New York, New York, Forenede Stater, 10065
    - Memorial Sloan-Kettering Cancer Center
  - New York, New York, Forenede Stater, 10065
    - Weill Medical College of Cornell University
  - New York, New York, Forenede Stater, 10016
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
  - Rochester, New York, Forenede Stater, 14642
    - University of Rochester
  - Rockville Centre, New York, Forenede Stater, 11570
    - Memorial Sloan Kettering Rockville Centre
  - Syracuse, New York, Forenede Stater, 13210
    - State University of New York Upstate Medical University
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28805
    - Asheville VA Medical Center
  - Clinton, North Carolina, Forenede Stater, 28328
    - Southeastern Medical Oncology Center-Clinton
  - Durham, North Carolina, Forenede Stater, 27710
    - Duke University Medical Center
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Wayne Memorial Hospital
  - Jacksonville, North Carolina, Forenede Stater, 28546
    - Southeastern Medical Oncology Center-Jacksonville
  - Wilson, North Carolina, Forenede Stater, 27893
    - Southeastern Medical Oncology Center-Wilson
- Ohio
  - Bellefontaine, Ohio, Forenede Stater, 43311
    - Mary Rutan Hospital
  - Canton, Ohio, Forenede Stater, 44708
    - Mercy Medical Center
  - Chillicothe, Ohio, Forenede Stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forenede Stater, 45220
    - Good Samaritan Hospital - Cincinnati
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forenede Stater, 45247
    - TriHealth Cancer Institute-Westside
  - Cincinnati, Ohio, Forenede Stater, 45255
    - TriHealth Cancer Institute-Anderson
  - Columbus, Ohio, Forenede Stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forenede Stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forenede Stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forenede Stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forenede Stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forenede Stater, 43222
    - Mount Carmel Health Center West
  - Columbus, Ohio, Forenede Stater, 43215
    - Columbus NCI Community Oncology Research Program
  - Delaware, Ohio, Forenede Stater, 43015
    - Grady Memorial Hospital
  - Lancaster, Ohio, Forenede Stater, 43130
    - Fairfield Medical Center
  - Marietta, Ohio, Forenede Stater, 45750
    - Marietta Memorial Hospital
  - Mount Vernon, Ohio, Forenede Stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Licking Memorial Hospital
  - Portsmouth, Ohio, Forenede Stater, 45662
    - Southern Ohio Medical Center
  - Springfield, Ohio, Forenede Stater, 45505
    - Springfield Regional Medical Center
  - Westerville, Ohio, Forenede Stater, 43081
    - Saint Ann's Hospital
  - Youngstown, Ohio, Forenede Stater, 44501
    - Tod Children's Hospital - Forum Health
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - University of Oklahoma Health Sciences Center
- Oregon
  - Baker City, Oregon, Forenede Stater, 97814
    - Saint Alphonsus Medical Center-Baker City
  - Bend, Oregon, Forenede Stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forenede Stater, 97015
    - Clackamas Radiation Oncology Center
  - Clackamas, Oregon, Forenede Stater, 97015
    - Providence Oncology and Hematology Care Southeast
  - Coos Bay, Oregon, Forenede Stater, 97420
    - Bay Area Hospital
  - Milwaukie, Oregon, Forenede Stater, 97222
    - Providence Milwaukie Hospital
  - Newberg, Oregon, Forenede Stater, 97132
    - Providence Newberg Medical Center
  - Ontario, Oregon, Forenede Stater, 97914
    - Saint Alphonsus Medical Center-Ontario
  - Oregon City, Oregon, Forenede Stater, 97045
    - Providence Willamette Falls Medical Center
  - Portland, Oregon, Forenede Stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forenede Stater, 97225
    - Providence Saint Vincent Medical Center
  - Portland, Oregon, Forenede Stater, 97239
    - Portland Veterans Administration Medical Center
- Pennsylvania
  - Allentown, Pennsylvania, Forenede Stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Bethlehem, Pennsylvania, Forenede Stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Danville, Pennsylvania, Forenede Stater, 17822
    - Geisinger Medical Center
  - Kittanning, Pennsylvania, Forenede Stater, 16201
    - Armstrong Center for Medicine and Health
  - Lewisburg, Pennsylvania, Forenede Stater, 17837
    - Geisinger Medical Oncology-Lewisburg
  - Monroeville, Pennsylvania, Forenede Stater, 15146
    - Forbes Hospital
  - Natrona Heights, Pennsylvania, Forenede Stater, 15065
    - Allegheny Valley Hospital
  - New Castle, Pennsylvania, Forenede Stater, 16105
    - Jameson Health System North Campus
  - Philadelphia, Pennsylvania, Forenede Stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Thomas Jefferson University Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15224
    - West Penn Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15213
    - UPMC-Magee Womens Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - UPMC-Shadyside Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15213
    - UPMC-Presbyterian Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15215
    - UPMC-Saint Margaret
  - Pittsburgh, Pennsylvania, Forenede Stater, 15237
    - UPMC-Passavant Hospital
  - Pottsville, Pennsylvania, Forenede Stater, 17901
    - Geisinger Medical Oncology-Pottsville
  - Reading, Pennsylvania, Forenede Stater, 19605
    - Penn State Health Saint Joseph Medical Center
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Guthrie Medical Group PC-Robert Packer Hospital
- South Carolina
  - Charleston, South Carolina, Forenede Stater, 29425
    - Medical University of South Carolina
  - Easley, South Carolina, Forenede Stater, 29640
    - Greenville Health System Cancer Institute-Easley
  - Greenville, South Carolina, Forenede Stater, 29605
    - Greenville Memorial Hospital
  - Greenville, South Carolina, Forenede Stater, 29605
    - Greenville Health System Cancer Institute-Butternut
  - Seneca, South Carolina, Forenede Stater, 29672
    - Greenville Health System Cancer Institute-Seneca
  - Spartanburg, South Carolina, Forenede Stater, 29307
    - Greenville Health System Cancer Institute-Spartanburg
- Tennessee
  - Chattanooga, Tennessee, Forenede Stater, 37404
    - Memorial Hospital
  - Hixson, Tennessee, Forenede Stater, 37343
    - Pulmonary Medicine Center of Chattanooga-Hixson
  - Knoxville, Tennessee, Forenede Stater, 37920
    - University of Tennessee - Knoxville
  - Ooltewah, Tennessee, Forenede Stater, 37363
    - Memorial GYN Plus
- Texas
  - Bryan, Texas, Forenede Stater, 77802
    - Saint Joseph Regional Cancer Center
  - Dallas, Texas, Forenede Stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Dallas, Texas, Forenede Stater, 75230
    - Medical City Dallas Hospital
  - Houston, Texas, Forenede Stater, 77030
    - M D Anderson Cancer Center
- Utah
  - American Fork, Utah, Forenede Stater, 84003
    - American Fork Hospital / Huntsman Intermountain Cancer Center
- Vermont
  - Berlin Corners, Vermont, Forenede Stater, 05602
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forenede Stater, 05405
    - University of Vermont College of Medicine
- Virginia
  - Charlottesville, Virginia, Forenede Stater, 22908
    - University of Virginia Cancer Center
  - Fredericksburg, Virginia, Forenede Stater, 22401
    - Mary Washington Hospital
  - Hampton, Virginia, Forenede Stater, 23666
    - Virginia Oncology Associates-Hampton
  - Hampton, Virginia, Forenede Stater, 23666
    - Sentara Cancer Institute at Sentara CarePlex Hospital
  - Norfolk, Virginia, Forenede Stater, 23507
    - Sentara Norfolk General Hospital
  - Norfolk, Virginia, Forenede Stater, 23502
    - Virginia Oncology Associates - Lake Wright
  - Richmond, Virginia, Forenede Stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - Williamsburg, Virginia, Forenede Stater, 23188
    - Sentara Williamsburg Regional Medical Center
- Washington
  - Aberdeen, Washington, Forenede Stater, 98520
    - Providence Regional Cancer System-Aberdeen
  - Anacortes, Washington, Forenede Stater, 98221
    - Cancer Care Center at Island Hospital
  - Auburn, Washington, Forenede Stater, 98001
    - MultiCare Auburn Medical Center
  - Bellevue, Washington, Forenede Stater, 98005
    - Swedish Cancer Institute-Eastside Oncology Hematology
  - Bellevue, Washington, Forenede Stater, 98004
    - Overlake Hospital Medical Center
  - Bellingham, Washington, Forenede Stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Bremerton, Washington, Forenede Stater, 98310
    - Harrison Medical Center
  - Burien, Washington, Forenede Stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forenede Stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forenede Stater, 98026
    - Swedish Medical Center-Edmonds
  - Enumclaw, Washington, Forenede Stater, 98022
    - Saint Elizabeth Hospital
  - Everett, Washington, Forenede Stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forenede Stater, 98003
    - Saint Francis Hospital
  - Issaquah, Washington, Forenede Stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forenede Stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Kirkland, Washington, Forenede Stater, 98034
    - Seattle Cancer Care Alliance at EvergreenHealth
  - Lacey, Washington, Forenede Stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forenede Stater, 98499
    - Saint Clare Hospital
  - Longview, Washington, Forenede Stater, 98632
    - PeaceHealth Saint John Medical Center
  - Mount Vernon, Washington, Forenede Stater, 98274
    - Skagit Valley Hospital
  - Olympia, Washington, Forenede Stater, 98506-5166
    - Providence - Saint Peter Hospital
  - Poulsbo, Washington, Forenede Stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Puyallup, Washington, Forenede Stater, 98372
    - MultiCare Good Samaritan Hospital
  - Seattle, Washington, Forenede Stater, 98109
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forenede Stater, 98195
    - University of Washington Medical Center
  - Seattle, Washington, Forenede Stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forenede Stater, 98101
    - Virginia Mason Medical Center
  - Seattle, Washington, Forenede Stater, 98107
    - Swedish Medical Center-Ballard Campus
  - Seattle, Washington, Forenede Stater, 98104
    - Minor and James Medical PLLC
  - Seattle, Washington, Forenede Stater, 98104
    - Pacific Gynecology Specialists
  - Seattle, Washington, Forenede Stater, 98112
    - Group Health Cooperative-Seattle
  - Seattle, Washington, Forenede Stater, 98122-4307
    - Swedish Medical Center-First Hill
  - Sedro-Woolley, Washington, Forenede Stater, 98284
    - United General Hospital
  - Shelton, Washington, Forenede Stater, 98584
    - Providence Regional Cancer System-Shelton
  - Spokane, Washington, Forenede Stater, 99204
    - Rockwood Cancer Treatment Center-DHEC-Downtown
  - Spokane, Washington, Forenede Stater, 99218
    - Evergreen Hematology and Oncology PS
  - Spokane, Washington, Forenede Stater, 99202
    - Cancer Care Northwest - Spokane South
  - Spokane, Washington, Forenede Stater, 99220
    - Rockwood Clinic
  - Spokane, Washington, Forenede Stater, 99218
    - Rockwood North Cancer Treatment Center
  - Spokane Valley, Washington, Forenede Stater, 99216
    - Rockwood Clinic Cancer Treatment Center-Valley
  - Tacoma, Washington, Forenede Stater, 98405
    - Northwest Medical Specialties PLLC
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - Franciscan Research Center-Northwest Medical Plaza
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Allenmore Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - Saint Joseph Medical Center
  - Vancouver, Washington, Forenede Stater, 98664
    - PeaceHealth Southwest Medical Center
  - Vancouver, Washington, Forenede Stater, 98684
    - Compass Oncology Vancouver
  - Walla Walla, Washington, Forenede Stater, 99362
    - Providence Saint Mary Regional Cancer Center
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Hospital and Clinics
  - Yakima, Washington, Forenede Stater, 98902
    - North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
  - Yelm, Washington, Forenede Stater, 98597
    - Providence Regional Cancer System-Yelm
- Wisconsin
  - Appleton, Wisconsin, Forenede Stater, 54911
    - Fox Valley Surgical Associates Limited
  - Madison, Wisconsin, Forenede Stater, 53792
    - University of Wisconsin Hospital and Clinics
  - Milwaukee, Wisconsin, Forenede Stater, 53226
    - Froedtert and the Medical College of Wisconsin
- Wyoming
  - Cody, Wyoming, Forenede Stater, 82414
    - Big Horn Basin Cancer Center
  - Cody, Wyoming, Forenede Stater, 82414
    - Billings Clinic-Cody
  - Sheridan, Wyoming, Forenede Stater, 82801
    - Welch Cancer Center

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Kvalifikationskriterier for forhåndsregistrering:

Perifer lungeknude ≤ 2 cm ved præoperativ CT-scanning og formodes at være lungekræft. Tumorens centrum, som det ses på CT, skal være placeret i den yderste tredjedel af lungen i enten det tværgående, koronale eller sagittale plan. Patienter med opaciteter af rent malet glas eller patologisk bekræftet N1- eller N2-sygdom er ikke kvalificerede.
Tumorplaceringen skal være egnet til enten lobar eller sublobar resektion (kile eller segment).
ECOG-ydelsesstatus på 0-2.
Ingen tidligere malignitet inden for 3 år bortset fra ikke-melanom hudkræft, overfladisk blærekræft eller CIS i livmoderhalsen.
Ingen forudgående kemoterapi eller strålebehandling for denne malignitet.
Ingen tegn på lokalt fremskreden eller metastatisk sygdom.
Alder ≥ 18 år

Intraoperativ randomiseringsberettigelseskriterier:

Histologisk bekræftelse af NSCLC (hvis ikke allerede opnået)
Bekræftelse af N0-status ved frysesektionsundersøgelse. Højresidede tumorer kræver, at nodeniveauer 4, 7 og 10 udtages og diagnosticeres som negative på frosset snit. Venstresidede tumorer kræver, at nodeniveauer 5 eller 6, 7 og 10 udtages og diagnosticeres som negative på frosset snit. Niveau 4 og 7 noder kan udtages ved mediastinoskopi, endobronchial ultralyd (EBUS) og/eller endoskopisk ultralyd (EUS), eller på tidspunktet for thorakotomi eller VATS-udforskning. Noder, der tidligere er udtaget ved mediastinoskopi (eller EBUS og/eller EUS), enten umiddelbart før eller inden for 6 uger efter den endelige kirurgiske procedure (thorakotomi eller VATS), behøver ikke at blive genudtaget.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Ingen (Åben etiket)

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Andet: Arm A Patienter gennemgår en standardoperation for lungekræft kaldet en lobektomi.	Procedure: lobektomi
Eksperimentel: Arm B Patenter gennemgår en begrænset resektion (segentektomi eller kileresektion), hvor en mindre del af lungen fjernes.	Procedure: segmentektomi eller kileresektion

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Tidsramme
sygdomsfri overlevelse Tidsramme: Op til 7 år	Op til 7 år

Sekundære resultatmål

Resultatmål	Tidsramme
samlet overlevelse Tidsramme: Op til 7 år	Op til 7 år
frekvens af loko-regionalt og systemisk tilbagefald Tidsramme: Op til 7 år	Op til 7 år
lungefunktion målt ved ekspiratorisk flowhastighed 6 måneder postoperativt Tidsramme: ved 6 måneder	ved 6 måneder

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Alliance for Clinical Trials in Oncology

Samarbejdspartnere

National Cancer Institute (NCI)

Efterforskere

Studiestol: Nasser Altorki, MD, Weill Medical College of Cornell University

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

12. oktober 2007

Primær færdiggørelse (Faktiske)

30. september 2025

Studieafslutning (Faktiske)

30. september 2025

Datoer for studieregistrering

Først indsendt

10. juli 2007

Først indsendt, der opfyldte QC-kriterier

10. juli 2007

Først opslået (Anslået)

11. juli 2007

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

22. januar 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

20. januar 2026

Sidst verificeret

1. januar 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

CALGB 140503
CALGB-140503
CDR0000555324 (Registry Identifier: NCI Physician Data Query)
NCI-2009-00447 (Registry Identifier: NCI Clinical Trial Reporting Program)

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Lungekræft

Seoul National University Hospital

Afsluttet

Effektiviteten af Lung Sono i One-lung Ventilation

One Lung Ventilation

Korea, Republikken
Seoul National University Hospital

Afsluttet

Forkonditionering af One-lung Ventilation

One Lung Ventilation

Korea, Republikken
Yonsei University

Afsluttet

Positivt endeekspiratorisk tryk og alveolær rekruttering til én lungeventilation

One Lung Ventilation

Korea, Republikken
Sichuan University
West China Hospital

Midlertidigt ikke tilgængelig

Ændringen af pulmonal blodgennemstrømning under én lungeventilation

One Lung Ventilation
Chinese Chronic Respiratory Disease Research Network

Rekruttering

Kohorteundersøgelse af lungeknudeintervention (LNICS)

Hændelse Lung Nodule

Kina
Mansoura University

Afsluttet

Sammenligning af tre metoder til PEEP-titrering under én lungeventilation i liggende stilling

One Lung Ventilation

Egypten
Dokuz Eylul University

Afsluttet

Evaluering af en lungeventilation med ultralyd ved thoraxkirurgiske operationer

One Lung Ventilation

Kalkun
Luca Brazzi
A.O.U. Città della Salute e della Scienza - Molinette Hospital

Ikke rekrutterer endnu

Videolaryngoskopi vs direkte laryngoskopi til placering af lumenrør med dobbelt lumen - Et multicenter randomiseret-kontrolleret forsøg (VOLCANO-undersøgelse) (VOLCANO)

Intubationskomplikation | One Lung Ventilation
Ankara Ataturk Sanatorium Training and Research...

Ikke rekrutterer endnu

Korrelation mellem iltnings- og mætningsindekser i enlungeventilation (OLV-INDICES)

One-lung Ventilation (OLV)

Tyrkiet (Türkiye)
Joseph D. Tobias

Afsluttet

Intracuff-tryk under en-lungeventilation hos spædbørn og børn

One-lung Ventilation (OLV)

Forenede Stater

Sammenligning af forskellige typer kirurgi til behandling af patienter med fase IA ikke-småcellet lungekræft

Et fase III randomiseret forsøg med lobektomi versus sublobar resektion for små (≤ 2 cm) perifer ikke-småcellet lungekræft

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Tidsramme

Sekundære resultatmål

Resultatmål

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Anslået)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Lungekræft

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Kosovo

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer