Effects of Learning and Food Form on Intake in Humans
Due to the rising incidence of obesity, much emphasis has been placed on identifying mechanisms of increased energy intake. At this point, the mechanisms responsible for the recent increase in obesity prevalence have not been thoroughly examined. Pre-ingestive influences, such as cognitive factors, may play a larger role in creating an energy surplus than previously thought. Expectations about the satiating effect of a food may override the post-ingestive influences in dictating further consumption. In addition, obese individuals may exhibit a decreased compensatory response to foods as compared to lean individuals.
Understanding the effects of energy content, food form, and learning on satiation, satiety, and energy intake will allow for a greater understanding of the mechanisms of energy imbalance as a whole. Food choice is dictated by sensory properties and post-ingestive effects. By utilizing foods with similar sensory properties, the acquired knowledge derived from ingesting these foods can be monitored by analyzing subsequent intake at the same meal and at subsequent eating occurrences. It is hypothesized that the liquid food form will elicit weaker dietary compensation; that is, energy intake at other eating events will not be adjusted to compensate for that food. In addition, it is posited that the lower energy food will cause lower compensation postprandially. By having participants consume the same test food daily over a two week learning period, it is thought that they will show improved dietary compensation when the initial testing is repeated due to learned associations between food properties and metabolism.
Studieoversigt
Status
Betingelser
Detaljeret beskrivelse
Undersøgelsestype
Tilmelding (Forventet)
Fase
- Ikke anvendelig
Kontakter og lokationer
Studiesteder
-
-
Indiana
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W. Lafayette, Indiana, Forenede Stater, 47907
- Purdue Univeristy
-
-
Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Beskrivelse
Inclusion Criteria:
- Weight stable (<3 kg weight change within last 3 months)
- Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
- Constant habitual diet patterns within last 3 months
- Willingness to eat a chocolate-flavored snack at test sessions and two week training period
- No allergies to any test foods
- Not planning to change use of medications known to influence appetite or metabolism
- Not diabetic
- No history of GI pathology
- Non-smoker for one year or more
Exclusion Criteria:
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Grundvidenskab
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Enkelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Eksperimentel: Energy dense beverage
Metabolic effects of consuming energy dense beverages before and after regular consumption
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Consumption of energy dense beverages for 2 weeks and monitoring physiological responses
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Eksperimentel: Energy dense solid food form
Metabolic effects of consuming energy dense solid foods before and after regular exposure.
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Effects of consuming energy dense solid food for two weeks on physiological responses
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Eksperimentel: Eenergy dilute beverages
Metabolic effects of consumption of energy dilute beverages on a regular basis.
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Effects of consuming energy dilute beverages for two weeks on physiological responses.
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Eksperimentel: Energy dilute solid food form
Metabolic effects of consuming energy dilute sold foods before and after regular exposure.
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Effects of consuming energy dilute solid food for two weeks on physiological responses
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
energy intake
Tidsramme: 12 weeks
|
Energy consumed over 12 weeks of intervention.
|
12 weeks
|
|
dietary compensation
Tidsramme: 12 weeks
|
spontaneous dietary adjustment in response to intervention
|
12 weeks
|
|
appetite
Tidsramme: 12 weeks
|
Effects of intervention on appetitive sensation such as hunger and fullness
|
12 weeks
|
|
effects of learning on energy intake
Tidsramme: 12 weeks
|
The effects of learning based on exposure to products that are high or low in energy and liquid or solid
|
12 weeks
|
|
Effects of food form on energy intake
Tidsramme: 12 weeks
|
The effects of food form on energy intake before and after chronic exposure to foods varying in food form and energy density
|
12 weeks
|
|
Effects of BMI on sensory learning
Tidsramme: 12 weeks
|
The effects of BMI on appetite, energy intake and dietary compensation
|
12 weeks
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Effects of personality traits on appetite, energy intake and compensation
Tidsramme: 12 weeks
|
Effects of personality traits related to feeding on appetite, energy intake and compensation following exposure to foods of different physical form, energy density and before and after learning.
|
12 weeks
|
Samarbejdspartnere og efterforskere
Sponsor
Publikationer og nyttige links
Datoer for undersøgelser
Studer store datoer
Studiestart
Primær færdiggørelse (Faktiske)
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Skøn)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Skøn)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- R01DK079913-3
- R01DK079913 (U.S. NIH-bevilling/kontrakt)
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