Effects of Learning and Food Form on Intake in Humans
Due to the rising incidence of obesity, much emphasis has been placed on identifying mechanisms of increased energy intake. At this point, the mechanisms responsible for the recent increase in obesity prevalence have not been thoroughly examined. Pre-ingestive influences, such as cognitive factors, may play a larger role in creating an energy surplus than previously thought. Expectations about the satiating effect of a food may override the post-ingestive influences in dictating further consumption. In addition, obese individuals may exhibit a decreased compensatory response to foods as compared to lean individuals.
Understanding the effects of energy content, food form, and learning on satiation, satiety, and energy intake will allow for a greater understanding of the mechanisms of energy imbalance as a whole. Food choice is dictated by sensory properties and post-ingestive effects. By utilizing foods with similar sensory properties, the acquired knowledge derived from ingesting these foods can be monitored by analyzing subsequent intake at the same meal and at subsequent eating occurrences. It is hypothesized that the liquid food form will elicit weaker dietary compensation; that is, energy intake at other eating events will not be adjusted to compensate for that food. In addition, it is posited that the lower energy food will cause lower compensation postprandially. By having participants consume the same test food daily over a two week learning period, it is thought that they will show improved dietary compensation when the initial testing is repeated due to learned associations between food properties and metabolism.
調査の概要
状態
条件
詳細な説明
研究の種類
入学 (予想される)
段階
- 適用できない
連絡先と場所
研究場所
-
-
Indiana
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W. Lafayette、Indiana、アメリカ、47907
- Purdue Univeristy
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-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Weight stable (<3 kg weight change within last 3 months)
- Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
- Constant habitual diet patterns within last 3 months
- Willingness to eat a chocolate-flavored snack at test sessions and two week training period
- No allergies to any test foods
- Not planning to change use of medications known to influence appetite or metabolism
- Not diabetic
- No history of GI pathology
- Non-smoker for one year or more
Exclusion Criteria:
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:基礎科学
- 割り当て:ランダム化
- 介入モデル:並列代入
- マスキング:独身
武器と介入
参加者グループ / アーム |
介入・治療 |
---|---|
実験的:Energy dense beverage
Metabolic effects of consuming energy dense beverages before and after regular consumption
|
Consumption of energy dense beverages for 2 weeks and monitoring physiological responses
|
実験的:Energy dense solid food form
Metabolic effects of consuming energy dense solid foods before and after regular exposure.
|
Effects of consuming energy dense solid food for two weeks on physiological responses
|
実験的:Eenergy dilute beverages
Metabolic effects of consumption of energy dilute beverages on a regular basis.
|
Effects of consuming energy dilute beverages for two weeks on physiological responses.
|
実験的:Energy dilute solid food form
Metabolic effects of consuming energy dilute sold foods before and after regular exposure.
|
Effects of consuming energy dilute solid food for two weeks on physiological responses
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
energy intake
時間枠:12 weeks
|
Energy consumed over 12 weeks of intervention.
|
12 weeks
|
dietary compensation
時間枠:12 weeks
|
spontaneous dietary adjustment in response to intervention
|
12 weeks
|
appetite
時間枠:12 weeks
|
Effects of intervention on appetitive sensation such as hunger and fullness
|
12 weeks
|
effects of learning on energy intake
時間枠:12 weeks
|
The effects of learning based on exposure to products that are high or low in energy and liquid or solid
|
12 weeks
|
Effects of food form on energy intake
時間枠:12 weeks
|
The effects of food form on energy intake before and after chronic exposure to foods varying in food form and energy density
|
12 weeks
|
Effects of BMI on sensory learning
時間枠:12 weeks
|
The effects of BMI on appetite, energy intake and dietary compensation
|
12 weeks
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Effects of personality traits on appetite, energy intake and compensation
時間枠:12 weeks
|
Effects of personality traits related to feeding on appetite, energy intake and compensation following exposure to foods of different physical form, energy density and before and after learning.
|
12 weeks
|
協力者と研究者
スポンサー
出版物と役立つリンク
研究記録日
主要日程の研究
研究開始
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (見積もり)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。