- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT02306616
CCC Project- Acute Coronary Syndrome
26. januar 2021 opdateret af: Dong ZHAO, Beijing Institute of Heart, Lung and Blood Vessel Diseases
Improving Care for Cardiovascular Disease in China: A Collaborative Project of AHA and CSC (CCC Project) - Acute Coronary Syndrome
To develop and implement quality improvement programs for the treatment of acute coronary syndrome (ACS) in China based on the successful experience of the AHA-Get with the Guidelines program.
This program will use data collection, analysis, feedback, and process improvement to extend the use of evidence-based guidelines throughout the healthcare system and improve patient care of acute coronary syndrome.
Studieoversigt
Status
Afsluttet
Betingelser
Undersøgelsestype
Observationel
Tilmelding (Faktiske)
124363
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
-
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Beijing, Kina
- Beijing An Zhen Hospital
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Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Barn
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Ingen
Køn, der er berettiget til at studere
Alle
Prøveudtagningsmetode
Ikke-sandsynlighedsprøve
Studiebefolkning
Hospitalized patients with acute coronary syndrome
Beskrivelse
Inclusion Criteria:
Hospitalized patients with discharge diagnosis as acute coronary syndrome (including STEMI, NSTEMI and UAP) in 150 tertiary and 100 secondary hospitals.
Exclusion Criteria:
None
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
---|---|---|
The overall composite of 11 performance measures for ACS care
Tidsramme: Duration of hospital stay, an expected average of 1 week
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Performance measures for ACS care including:
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Duration of hospital stay, an expected average of 1 week
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Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Efterforskere
- Ledende efterforsker: Dong Zhao, Ph. D, Beijing Institute of Heart, Lung and Blood Vessel Diseases
Publikationer og nyttige links
Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.
Generelle publikationer
- Hao Y, Liu J, Liu J, Smith SC Jr, Huo Y, Fonarow GC, Ma C, Ge J, Taubert KA, Morgan L, Guo Y, Zhang Q, Wang W, Zhao D; CCC-ACS Investigators. Rationale and design of the Improving Care for Cardiovascular Disease in China (CCC) project: A national effort to prompt quality enhancement for acute coronary syndrome. Am Heart J. 2016 Sep;179:107-15. doi: 10.1016/j.ahj.2016.06.005. Epub 2016 Jun 18.
- Yang Q, Wang Y, Liu J, Liu J, Hao Y, Smith SC Jr, Huo Y, Fonarow GC, Ma C, Ge J, Taubert KA, Morgan L, Guo Y, Wang W, Zhou Y, Zhao D; CCC-ACS Investigators. Invasive Management Strategies and Antithrombotic Treatments in Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome in China: Findings From the Improving CCC Project (Care for Cardiovascular Disease in China). Circ Cardiovasc Interv. 2017 Jun;10(6):e004750. doi: 10.1161/CIRCINTERVENTIONS.116.004750.
- Zhao G, Zhou M, Ma C, Huo Y, Smith SC Jr, Fonarow GC, Ge J, Han Y, Liu J, Hao Y, Liu J, Wang X, Taubert KA, Morgan L, Zhao D, Nie S; CCC-ACS Investigators. In-Hospital Outcomes of Dual Loading Antiplatelet Therapy in Patients 75 Years and Older With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Findings From the CCC-ACS (Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome) Project. J Am Heart Assoc. 2018 Mar 30;7(7):e008100. doi: 10.1161/JAHA.117.008100.
- Zhou M, Liu J, Hao Y, Liu J, Huo Y, Smith SC Jr, Ge J, Ma C, Han Y, Fonarow GC, Taubert KA, Morgan L, Yang N, Xing Y, Zhao D; CCC-ACS Investigators. Prevalence and in-hospital outcomes of diabetes among patients with acute coronary syndrome in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome Project. Cardiovasc Diabetol. 2018 Nov 27;17(1):147. doi: 10.1186/s12933-018-0793-x.
- Xing Y, Liu J, Hao Y, Liu J, Huo Y, Smith SC Jr, Ge J, Ma C, Han Y, Fonarow GC, Taubert KA, Morgan L, Yang N, Zhou M, Zhao D; CCC-ACS Investigators. Prehospital statin use and low-density lipoprotein cholesterol levels at admission in acute coronary syndrome patients with history of myocardial infarction or revascularization: Findings from the Improving Care for Cardiovascular Disease in China (CCC) project. Am Heart J. 2019 Jun;212:120-128. doi: 10.1016/j.ahj.2019.02.019. Epub 2019 Mar 13.
- Yang N, Liu J, Liu J, Hao Y, Huo Y, Smith SC Jr, Ge J, Ma C, Han Y, Fonarow GC, Taubert KA, Morgan L, Zhou M, Xing Y, Zhao D; CCC-ACS Investigators. Performance on management strategies with Class I Recommendation and A Level of Evidence among hospitalized patients with non-ST-segment elevation acute coronary syndrome in China: Findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS) project. Am Heart J. 2019 Jun;212:80-90. doi: 10.1016/j.ahj.2019.02.012. Epub 2019 Mar 4.
- Hao Y, Liu J, Liu J, Yang N, Smith SC Jr, Huo Y, Fonarow GC, Ge J, Taubert KA, Morgan L, Zhou M, Xing Y, Ma CS, Han Y, Zhao D. Sex Differences in In-Hospital Management and Outcomes of Patients With Acute Coronary Syndrome. Circulation. 2019 Apr 9;139(15):1776-1785. doi: 10.1161/CIRCULATIONAHA.118.037655.
- Gong W, Yan Y, Wang X, Zheng W, Smith SC Jr, Fonarow GC, Morgan L, Liu J, Zhao D, Ma C, Han Y, Montalescot G, Nie S; CCC-ACS Investigators. Risk Factors for In-Hospital Cardiac Arrest in Patients With ST-Segment Elevation Myocardial Infarction. J Am Coll Cardiol. 2022 Nov 8;80(19):1788-1798. doi: 10.1016/j.jacc.2022.08.797.
- Wang Y, Yang N, Suo M, Liu X, Wang Z, Zhang X, Liu J, Zhao D, Wu X; CCC-ACS Investigators. In-hospital outcomes of Ticagrelor versus Clopidogrel in high bleeding risk patients with acute coronary syndrome: Findings from the CCC-ACS project. Thromb Res. 2022 Aug;216:43-51. doi: 10.1016/j.thromres.2022.04.004. Epub 2022 May 10.
- Xu S, Li Z, Yang T, Li L, Song X, Hao Y, Smith SC, Fonarow GC, Morgan L, Liu J, Liu J, Zhao D, Yang Q, Zhou X, Li Y. Association between Early Oral beta-Blocker Therapy and Risk for In-Hospital Major Bleeding after Percutaneous Coronary Intervention for Acute Coronary Syndrome: Findings from CCC-ACS Project. Eur Heart J Qual Care Clin Outcomes. 2022 Jun 17:qcac036. doi: 10.1093/ehjqcco/qcac036. Online ahead of print.
- Lin YW, Huang JL, Wei XB, Jiang M, Ran P, Li J, Qiu J, Zhong Q, Zhou YL, Chen JY, Yu DQ. Estimated glomerular filtration rate derived from different formulas and prognosis in acute coronary syndrome: Findings from the improving care for cardiovascular disease in China-acute coronary syndrome project. Am J Med Sci. 2022 Nov;364(5):565-574. doi: 10.1016/j.amjms.2021.10.034. Epub 2022 Jun 2.
- Yang JQ, Ran P, Li J, Zhong Q, Smith SC Jr, Wang Y, Fonarow GC, Qiu J, Morgan L, Wei XB, Chen XB, Huang JL, Hao YC, Zhou YL, Siu CW, Zhao D, Chen JY, Yu DQ. A Risk Stratification Scheme for In-Hospital Cardiogenic Shock in Patients With Acute Myocardial Infarction. Front Cardiovasc Med. 2022 Mar 4;9:793497. doi: 10.3389/fcvm.2022.793497. eCollection 2022.
- Zhou M, Zhang J, Liu J, Smith SC Jr, Ma C, Ge J, Huo Y, Fonarow GC, Liu J, Hao Y, Gao F, Sun Y, Morgan L, Yang N, Hu G, Zeng Y, Han Y, Zhao D; CCC-ACS Investigators. Proton Pump Inhibitors and In-Hospital Gastrointestinal Bleeding in Patients With Acute Coronary Syndrome Receiving Dual Antiplatelet Therapy. Mayo Clin Proc. 2022 Apr;97(4):682-692. doi: 10.1016/j.mayocp.2021.11.037. Epub 2022 Feb 12.
- Wang X, Zhao G, Zhou M, Ma C, Ge J, Huo Y, Smith SC Jr, Fonarow GC, Hao Y, Liu J, Morgan L, Gong W, Yan Y, Liu J, Zhao D, Han Y, Nie S. Trends in Bleeding Events Among Patients With Acute Coronary Syndrome in China, 2015 to 2019: Insights From the CCC-ACS Project. Front Cardiovasc Med. 2021 Dec 13;8:769165. doi: 10.3389/fcvm.2021.769165. eCollection 2021.
- Yang Q, Sun D, Pei C, Zeng Y, Wang Z, Li Z, Hao Y, Song X, Li Y, Liu G, Tang Y, Smith SC, Han Y, Huo Y, Ge J, Ma C, Fonarow GC, Morgan L, Liu J, Liu J, Zhou M, Zhao D, Zhou Y, Zhou X; CCC-ACS Investigators. LDL cholesterol levels and in-hospital bleeding in patients on high-intensity antithrombotic therapy: findings from the CCC-ACS project. Eur Heart J. 2021 Aug 31;42(33):3175-3186. doi: 10.1093/eurheartj/ehab418.
- Yang L, Ye N, Wang G, Bian W, Xu F, Zhao D, Liu J, Hao Y, Liu J, Yang N, Cheng H; CCC-ACS. The association between atrial fibrillation and in-hospital outcomes in chronic kidney disease patients with acute coronary syndrome: findings from the improving care for cardiovascular disease in China-acute coronary syndrome (CCC-ACS) project. BMC Cardiovasc Disord. 2021 Jul 17;21(1):345. doi: 10.1186/s12872-021-02125-z.
- Ran P, Yang JQ, Li J, Li G, Wang Y, Qiu J, Zhong Q, Wang Y, Wei XB, Huang JL, Siu CW, Zhou YL, Zhao D, Yu DQ, Chen JY. A risk score to predict in-hospital mortality in patients with acute coronary syndrome at early medical contact: results from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS) Project. Ann Transl Med. 2021 Jan;9(2):167. doi: 10.21037/atm-21-31.
- Zhao X, Kang Y, Wang X, Yang X, Ai G, Liu Y, Xu P, Zhang J, Gu C, Zhang Y, Hao Y, Zhao D, Han Y; CCC investigators. Clinical significance of glycated hemoglobin in acute coronary syndrome patients from the CCC-ACS project : Findings from a multicenter retrospective observational study. Herz. 2021 Sep;46(Suppl 2):287-294. doi: 10.1007/s00059-020-04999-9. Epub 2020 Nov 24.
- Hu G, Zhou M, Liu J, Smith SC Jr, Ma C, Ge J, Huo Y, Fonarow GC, Hao Y, Liu J, Taubert KA, Morgan L, Yang N, Zeng Y, Han Y, Zhao D; CCC-ACS Investigators. Smoking and Provision of Smoking Cessation Interventions among Inpatients with Acute Coronary Syndrome in China: Findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome Project. Glob Heart. 2020 Oct 23;15(1):72. doi: 10.5334/gh.784.
- Ye N, Yang L, Wang G, Bian W, Xu F, Ma C, Zhao D, Liu J, Hao Y, Liu J, Yang N, Cheng H; CCC-ACS. Admission fasting plasma glucose is associated with in-hospital outcomes in patients with acute coronary syndrome and diabetes: findings from the improving Care for Cardiovascular Disease in China - Acute Coronary Syndrome (CCC-ACS) project. BMC Cardiovasc Disord. 2020 Aug 20;20(1):380. doi: 10.1186/s12872-020-01662-3. Erratum In: BMC Cardiovasc Disord. 2021 Jul 22;21(1):349.
Hjælpsomme links
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart
1. november 2014
Primær færdiggørelse (Faktiske)
1. december 2020
Studieafslutning (Faktiske)
1. december 2020
Datoer for studieregistrering
Først indsendt
29. november 2014
Først indsendt, der opfyldte QC-kriterier
29. november 2014
Først opslået (Skøn)
3. december 2014
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
27. januar 2021
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
26. januar 2021
Sidst verificeret
1. januar 2021
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- CCC-ACS-2014
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .
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