A 14-Day Study of Racivir When Used in Combination in HIV-Infected Males

Inclusion Criteria

Subjects may be eligible to participate if they:

• Are males with HIV infection with a positive HIV antibody test
• Have an HIV-RNA copy number of ≥ 5000 copies/ml (Roche assay)
• Have CD4+ cell counts ≥ 50 cells/ml
• Are 18-45 years of age, inclusive
• Have a body mass index (BMI) ≥ 18 kg/m2
• Are antiretroviral nucleoside reverse transcriptase inhibitor-naive
• Have read and understand the informed consent,and is able and willing to comply with study procedures

Exclusion Criteria

Subjects may not participate if they:

• Have clinically significant ECG abnormalities
• Have clinically significant abnormalities in any safety laboratory parameters
• Have an ALT value ≥ 3xUNL
• Have previously participated in this trial
• Have participated in another trial of an investigational drug within the last 3 months or are currently participating in another trial of an investigational drug
• Have a history of chronic alcohol or drug abuse within the last 6 months
• Have a positive urine drug screening
• Have a positive alcohol breath test
• Have any medical or psychiatric condition, which in the opinion of the investigator would jeopardize or compromise the subject's ability to participate in this trial
• Have a known hypersensitivity to any components of the trial medication or comparative drugs as stated in this protocol