Un estudio de LY2127399 en participantes con lupus eritematoso sistémico
18 de junio de 2018 actualizado por: Eli Lilly and Company
Estudio de fase 3, multicéntrico, aleatorizado, doble ciego, controlado con placebo para evaluar la eficacia y seguridad de LY2127399 subcutáneo en pacientes con lupus eritematoso sistémico (LES)
El propósito de este estudio de LES es evaluar la eficacia, seguridad y tolerabilidad de dos dosis diferentes de LY2127399 administradas además de la terapia de atención estándar en participantes con LES activo.
Descripción general del estudio
Estado
Terminado
Intervención / Tratamiento
Tipo de estudio
Intervencionista
Inscripción (Actual)
1124
Fase
- Fase 3
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Ubicaciones de estudio
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Malvern East, Australia, 3145
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New South Wales
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St Leonards, New South Wales, Australia, 2065
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Queensland
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Cairns, Queensland, Australia, 4870
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Maroochydore, Queensland, Australia, 4558
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Victoria
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Clayton, Victoria, Australia, 3168
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Heidelberg, Victoria, Australia, 3081
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Campinas, Brasil, 13015-011
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Goiania, Brasil, 74110-120
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Juiz De Fora, Brasil, 36010-570
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Porto Alegre, Brasil, 91350-200
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Salvador, Brasil, 40050-410
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São Paulo, Brasil, 04039-901
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Ontario
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Hamilton, Ontario, Canadá, L8N 3Z5
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Quebec
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Trois-Rivieres, Quebec, Canadá, G8Z 1Y2
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Cuenca, Ecuador, EC010150
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Guayaquil, Ecuador, 90110321
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Quito, Ecuador, 17
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Barcelona, España, 08035
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Bilbao, España, 48013
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La Coruña, España, 15006
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Las Palmas De Gran Canaria, España, 35010
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Madrid, España, 28040
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Málaga, España, 29010
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Santiago De Compostela, España, 15706
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Sevilla, España, 41071
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Vigo, España, 36200
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Alabama
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Anniston, Alabama, Estados Unidos, 36207
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Birmingham, Alabama, Estados Unidos, 35216
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Arizona
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Gilbert, Arizona, Estados Unidos, 85234
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Scottsdale, Arizona, Estados Unidos, 85258
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Tempe, Arizona, Estados Unidos, 85282
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Arkansas
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Malvern, Arkansas, Estados Unidos, 72104
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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California
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Covina, California, Estados Unidos, 91723
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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El Cajon, California, Estados Unidos, 92020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Escondido, California, Estados Unidos, 92027
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La Mesa, California, Estados Unidos, 91941
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Lakewood, California, Estados Unidos, 90712
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Los Alamitos, California, Estados Unidos, 90720
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Los Angeles, California, Estados Unidos, 90095
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Pasadena, California, Estados Unidos, 91107
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Riverside, California, Estados Unidos, 92506
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San Diego, California, Estados Unidos, 92108
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San Gabriel, California, Estados Unidos, 91776
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Santa Barbara, California, Estados Unidos, 93108
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Van Nuys, California, Estados Unidos, 91405
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Westlake Village, California, Estados Unidos, 91361
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Whittier, California, Estados Unidos, 90606
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Colorado
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Aurora, Colorado, Estados Unidos, 80045
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District of Columbia
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Washington, District of Columbia, Estados Unidos, 20060
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Florida
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Aventura, Florida, Estados Unidos, 33180
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DeBary, Florida, Estados Unidos, 32713
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Miami, Florida, Estados Unidos, 33175
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Naples, Florida, Estados Unidos, 34102
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New Port Richey, Florida, Estados Unidos, 34652
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Ormond Beach, Florida, Estados Unidos, 32174
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Pensacola, Florida, Estados Unidos, 32514
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Pinellas Park, Florida, Estados Unidos, 33781
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Plantation, Florida, Estados Unidos, 33324
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South Miami, Florida, Estados Unidos, 33143
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Tampa, Florida, Estados Unidos, 33603
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Vero Beach, Florida, Estados Unidos, 32960
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Georgia
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Atlanta, Georgia, Estados Unidos, 30303
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Duluth, Georgia, Estados Unidos, 30096
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Lithonia, Georgia, Estados Unidos, 30038
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Idaho
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Meridian, Idaho, Estados Unidos, 83642
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Illinois
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Chicago, Illinois, Estados Unidos, 60612
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Rockford, Illinois, Estados Unidos, 61107
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Indiana
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Fort Wayne, Indiana, Estados Unidos, 46804
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Granger, Indiana, Estados Unidos, 46530
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Indianapolis, Indiana, Estados Unidos, 46202
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Louisiana
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Monroe, Louisiana, Estados Unidos, 71203
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Maine
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Portland, Maine, Estados Unidos, 04102
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Maryland
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Cumberland, Maryland, Estados Unidos, 21502
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Michigan
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Saint Clair Shores, Michigan, Estados Unidos, 48081
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Minnesota
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Duluth, Minnesota, Estados Unidos, 55805
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Mississippi
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Hattiesburg, Mississippi, Estados Unidos, 39402
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Missouri
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Saint Louis, Missouri, Estados Unidos, 63117
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Nevada
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Las Vegas, Nevada, Estados Unidos, 89128
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New Hampshire
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Nashua, New Hampshire, Estados Unidos, 03060
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New Jersey
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Freehold, New Jersey, Estados Unidos, 07728
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Voorhees, New Jersey, Estados Unidos, 08043
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New Mexico
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Las Cruces, New Mexico, Estados Unidos, 88011
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New York
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Albany, New York, Estados Unidos, 12206
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Brooklyn, New York, Estados Unidos, 11201
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Manhasset, New York, Estados Unidos, 11030
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New York, New York, Estados Unidos, 10021
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New York, New York, Estados Unidos, 10016
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Plainview, New York, Estados Unidos, 11803
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Roslyn, New York, Estados Unidos, 11576
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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North Carolina
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Chapel Hill, North Carolina, Estados Unidos, 27599
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Charlotte, North Carolina, Estados Unidos, 28204
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Raleigh, North Carolina, Estados Unidos, 27617
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Rocky Mount, North Carolina, Estados Unidos, 27804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ohio
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Cincinnati, Ohio, Estados Unidos, 45219
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Cleveland, Ohio, Estados Unidos, 44109
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Toledo, Ohio, Estados Unidos, 43606
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Oklahoma
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Oklahoma City, Oklahoma, Estados Unidos, 73104
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pennsylvania
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Duncansville, Pennsylvania, Estados Unidos, 16635
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Wyomissing, Pennsylvania, Estados Unidos, 19610
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South Carolina
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Charleston, South Carolina, Estados Unidos, 29425
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tennessee
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Cookeville, Tennessee, Estados Unidos, 38501
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Knoxville, Tennessee, Estados Unidos, 37909
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Memphis, Tennessee, Estados Unidos, 38163
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Nashville, Tennessee, Estados Unidos, 37203
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Texas
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Amarillo, Texas, Estados Unidos, 79124
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Austin, Texas, Estados Unidos, 78745
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Nassau Bay, Texas, Estados Unidos, 77058
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Round Rock, Texas, Estados Unidos, 78665
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San Antonio, Texas, Estados Unidos, 78232
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Victoria, Texas, Estados Unidos, 77901
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Utah
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Saint George, Utah, Estados Unidos, 84790
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Washington
-
Seattle, Washington, Estados Unidos, 98104
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Spokane, Washington, Estados Unidos, 99204
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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West Virginia
-
Clarksburg, West Virginia, Estados Unidos, 26301
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Chelyabinsk, Federación Rusa, 454076
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ekaterinburg, Federación Rusa, 620012
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kazan, Federación Rusa, 420097
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kemerovo, Federación Rusa, 650099
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Moscow, Federación Rusa, 125101
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Orenburg, Federación Rusa, 460018
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Saint Petersburg, Federación Rusa, 197089
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tomsk, Federación Rusa, 634063
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Yaroslavl, Federación Rusa, 150023
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Orleans, Francia, 45000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Strasbourg, Francia, 67091
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Budapest, Hungría, 1027
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Debrecen, Hungría, 4032
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gyor, Hungría, 9023
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gyula, Hungría, 5700
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Szeged, Hungría, 6720
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bangalore, India, 560043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gujarat, India, 380015
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Haryana, India, 122001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hyderabaad, India, 500082
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kormangala, India, 560034
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pune, India, 411007
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Trivandrum, India, 695011
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Haifa, Israel, 34362
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kfar Saba, Israel, 44281
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Petah Tikva, Israel, 49100
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tel Hashomer, Israel, 52651
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Zerifin, Israel, 70300
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Riga, Letonia, LV-1002
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kota Kinabalu, Malasia, 88586
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kuala Lumpur, Malasia, 59100
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Guadalajara, México, 44650
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Merida, México, 97130
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Mexico City, México, 06090
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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San Luis, México, 78240
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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San Luis Potosi, México, 78200
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tijuana, México, 22010
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hamilton, Nueva Zelanda, 3204
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Otahuhu, Nueva Zelanda, 1640
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Takapuna, Nueva Zelanda, 622
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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London, Reino Unido, SE1 7EH
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Cambridgeshire
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Cambridge, Cambridgeshire, Reino Unido, CB2 0QQ
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Dorset
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Poole, Dorset, Reino Unido, BH15 2JB
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Greater London
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London, Greater London, Reino Unido, E11 1NR
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kent
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Maidstone, Kent, Reino Unido, ME16 9QQ
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Lancashire
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Wigan, Lancashire, Reino Unido, WN6 0LW
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Brasov, Rumania, 500283
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bucharest, Rumania, 020475
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Cluj-Napoca, Rumania, 400006
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Galati, Rumania, 800587
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Iasi, Rumania, 700656
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Targu Mures, Rumania, 540136
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Belgrade, Serbia, 11000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kragujevac, Serbia, 34000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Niska Banja, Serbia, 18205
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Novi Sad, Serbia, 21000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Cape Town, Sudáfrica, 7925
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Durban, Sudáfrica, 4001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Stellenbosch, Sudáfrica, 7600
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Changhua, Taiwán, 500
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hualien, Taiwán, 970
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kaohsiung, Taiwán, 833
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Taichung, Taiwán, 40705
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Taichung City, Taiwán, 40201
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Taipei, Taiwán, 10630
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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La Marsa, Túnez, 2070
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Monastir, Túnez, 5000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Sfax, Túnez, 3029
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Sousse, Túnez, 4000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tunis, Túnez, 1008
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tunis Monfleury, Túnez, 1008
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
18 años y mayores (ADULTO, MAYOR_ADULTO)
Acepta Voluntarios Saludables
No
Géneros elegibles para el estudio
Todos
Descripción
Criterios de inclusión:
- Diagnóstico clínico de LES según lo definido por los criterios del American College of Rheumatology (ACR)
- Tener anticuerpos antinucleares (ANA) positivos
- Aceptar no quedar embarazada durante el transcurso del ensayo
- Tener una puntuación de cribado SELENA-SLEDAI ≥6. (El participante debe exhibir activamente todos los síntomas calificados en la evaluación SELENA-SLEDAI el día de la evaluación).
Criterio de exclusión:
- Tiene enfermedad renal lúpica grave activa
- Tiene enfermedad activa del Sistema Nervioso Central o neurológica periférica
- Haber recibido inmunoglobulina intravenosa (IVIg) dentro de los 180 días posteriores a la aleatorización
- Tiene una infección activa o reciente dentro de los 30 días posteriores a la detección
- Haber tenido una infección grave dentro de los 90 días posteriores a la aleatorización.
- Tener evidencia o dar positivo para Hepatitis B
- Tiene hepatitis C
- ¿Son positivos para el virus de la inmunodeficiencia humana (VIH)?
- Tener evidencia de tuberculosis activa o latente (TB)
- Presencia de anomalías de laboratorio significativas en el cribado
- Haber tenido una neoplasia maligna en los últimos 5 años, excepto carcinoma de cuello uterino in situ o de células basales o células epiteliales escamosas de la piel que se resecaron por completo sin recurrencia en los 3 años anteriores a la aleatorización
- Ha recibido más de 40 mg de prednisona o equivalente en los últimos 30 días
- Ha cambiado su dosis de medicamento antipalúdico en los últimos 30 días
- Ha cambiado su dosis de medicamento inmunosupresor en los últimos 90 días
- Haber recibido previamente rituximab
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: TRATAMIENTO
- Asignación: ALEATORIZADO
- Modelo Intervencionista: PARALELO
- Enmascaramiento: CUADRUPLICAR
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
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PLACEBO_COMPARADOR: Placebo
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Administrado mediante inyección subcutánea durante 52 semanas.
También se administrará una dosis de carga correspondiente en la primera dosis.
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EXPERIMENTAL: LY2127399 cada 2 semanas
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120 mg administrados mediante inyección subcutánea durante 52 semanas.
Se administrará una dosis de carga de 240 mg como primera dosis del fármaco del estudio.
|
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EXPERIMENTAL: LY2127399 cada 4 semanas
Durante el Período de tratamiento, con fines ciegos, los participantes alternarán inyecciones de LY2127399 e inyecciones de placebo cada 2 semanas.
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Administrado mediante inyección subcutánea durante 52 semanas.
120 mg administrados mediante inyección subcutánea durante 52 semanas.
Se administrará una dosis de carga de 240 mg como primera dosis del fármaco del estudio.
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Porcentaje de participantes que lograron una respuesta del índice de respuesta SLE en la semana 52
Periodo de tiempo: 52 semanas
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Porcentaje de participantes con una reducción de ≥ 5 puntos desde el inicio en la puntuación SELENA SLEDAI y sin empeoramiento (aumento de < 0,30 puntos desde el inicio) en la PGA, y sin una nueva puntuación del dominio de órganos BILAG A o 2 nuevas puntuaciones del dominio de órganos BILAG B en comparación con el inicio . SELENA SLEDAI se calcula a partir de 24 descriptores individuales en 9 sistemas de órganos; 0 indica enfermedad inactiva y la puntuación teórica máxima es 105; las puntuaciones > 20 son raras. PGA es una escala analógica visual que se puntúa de 0 a 3 (0=ninguno, 1=leve, 2=moderado, 3=grave). BILAG utiliza una puntuación única para cada uno de los 9 dominios de órganos; el rango es de grave (A) a sin enfermedad (E). Los participantes que no pudieron cumplir con los requisitos de medicamentos concomitantes permitidos se consideraron no respondedores, al igual que los participantes que abandonaron o a los que les faltaban los datos de la Semana 52. |
52 semanas
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Cambio desde el inicio hasta las 52 semanas en el nivel de anti-ácido desoxirribonucleico de doble cadena (Anti-dsDNA)
Periodo de tiempo: Línea de base, 52 semanas
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El anti-ácido desoxirribonucleico de doble cadena (anti-dsDNA) es un analito de laboratorio que se utiliza para ayudar en el diagnóstico de LES.
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Línea de base, 52 semanas
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Cambio desde el inicio hasta el punto final de 52 semanas en la puntuación del índice de actividad de la enfermedad del lupus eritematoso sistémico (SLEDAI2K)
Periodo de tiempo: Línea de base, 52 semanas
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La puntuación del SLE Disease Activity Index 2000 (SLEDAI-2K) es un índice ponderado y acumulativo de la actividad de la enfermedad del lupus.
SLEDAI-2K se calcula a partir de 24 descriptores individuales en 9 sistemas de órganos; 0 indica enfermedad inactiva y la puntuación teórica máxima es 105.
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Línea de base, 52 semanas
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Tiempo hasta el primer brote severo de LES (SFI)
Periodo de tiempo: Línea de base hasta las 52 semanas
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El SFI utiliza la puntuación del índice de actividad de la enfermedad de SELENA-SLEDAI, escenarios de actividad de la enfermedad, cambios de tratamiento y PGA para definir brotes leves/moderados y graves. El índice tiene en cuenta el cambio absoluto en las puntuaciones totales, los síntomas nuevos o que empeoran y los aumentos en el uso de corticosteroides o la hospitalización debido a la actividad de la enfermedad. El tiempo hasta el primer brote grave de LES (SFI) (en días) se calcula como: (Fecha de inicio del primer brote grave de LES (SFI) - Fecha de aleatorización + 1). |
Línea de base hasta las 52 semanas
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Cambio desde el punto de referencia hasta el punto final de 52 semanas en las puntuaciones del Inventario Breve de Fatiga (BFI)
Periodo de tiempo: Línea de base, 52 semanas
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Una escala informada por los participantes que mide la gravedad de la fatiga en función de la peor fatiga experimentada durante las últimas 24 horas.
Los puntajes de gravedad variaron de 0 (sin fatiga) a 10 (fatiga tan severa como puedas imaginar).
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Línea de base, 52 semanas
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Tiempo hasta el primer nuevo grupo de evaluación de lupus de las Islas Británicas (BILAG A) o 2 brotes nuevos de BILAG B SLE
Periodo de tiempo: Línea de base hasta las 52 semanas
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El instrumento del Grupo de Evaluación del Lupus de las Islas Británicas (BILAG) evalúa la actividad global de la enfermedad en 9 dominios de sistemas de órganos. Los brotes de BILAG se evalúan para cada uno de los 9 dominios de órganos utilizando las reglas del índice de brotes de BILAG2004; A es un brote severo y B es un brote moderado. El tiempo hasta el primer brote de BILAG A o dos brotes de BILAG B (en días) se calcula como: (Fecha de inicio del primer brote de BILAG A o dos brotes de BILAG B - Fecha de aleatorización + 1). Los dos brotes de BILAG B deben ocurrir en diferentes dominios en la misma visita. |
Línea de base hasta las 52 semanas
|
|
Porcentaje de participantes con un aumento en la dosis de corticosteroides a las 52 semanas
Periodo de tiempo: 52 semanas
|
Un aumento en los corticosteroides en una visita se definió como un cambio desde el inicio superior a 2,5 mg/día en la dosis de prednisona o equivalente usando la dosis diaria promedio de corticosteroides tomada desde la visita programada anterior.
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52 semanas
|
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Cambio desde el inicio hasta el punto final de 52 semanas en la puntuación de actividad de la enfermedad de SELENA-SLEDAI
Periodo de tiempo: Línea de base, 52 semanas
|
Evaluación nacional de la seguridad de los estrógenos en el lupus eritematoso: la puntuación del Índice de actividad de la enfermedad del LES (SELENA-SLEDAI) es un índice ponderado y acumulativo de la actividad de la enfermedad del lupus.
SELENA-SLEDAI se calcula a partir de 24 descriptores individuales en 9 sistemas de órganos; 0 indica enfermedad inactiva y la puntuación teórica máxima es 105.
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Línea de base, 52 semanas
|
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Porcentaje de participantes capaces de disminuir la dosis de prednisona o equivalente sin aumento en la actividad de la enfermedad en la semana 52
Periodo de tiempo: 52 semanas
|
Un participante logra efectos de ahorro de corticosteroides (enfermedad inactiva) si ha cumplido con los siguientes criterios durante las semanas 24 a 52; capaz de disminuir su dosis de prednisona o equivalente a 7,5 mg/día o menos, tiene enfermedad quiescente (puntaje BILAG C o mejor en los nueve sistemas), y no hay brotes de BILAG A o B en los tres meses anteriores, sin un aumento en ninguno de los dos antipalúdicos o inmunosupresores en o antes de la visita.
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52 semanas
|
|
Cambio desde el inicio hasta el final de la semana 52 en la evaluación global del médico (PGA)
Periodo de tiempo: Línea de base, 52 semanas
|
PGA es una evaluación de un solo elemento calificada por un médico del nivel actual de actividad de la enfermedad del participante medido en una escala analítica visual continua de 100 milímetros (mm) con puntos de referencia de 0, 1, 2 y 3 de izquierda a derecha correspondiente a no, leve actividad de la enfermedad de LES moderada, moderada y grave.
Las puntuaciones se presentan de 0 a 100.
Sin empeoramiento definido como un aumento de ≤ 0,30 puntos desde el inicio.
|
Línea de base, 52 semanas
|
|
Cambio desde el inicio hasta las puntuaciones de dominio de la calidad de vida del lupus (LupusQOL) al final de la semana 52
Periodo de tiempo: Línea de base, 52 semanas
|
El LupusQoL es un cuestionario de autoinforme de 34 elementos, específico de la enfermedad, diseñado para medir la calidad de vida relacionada con la salud (HRQoL) de los participantes con LES dentro de 8 dominios. Las respuestas se basan en una escala Likert de 5 puntos donde 0 ( todo el tiempo) a 4 (nunca).
Se informa una puntuación de LupusQoL para cada dominio en una escala de 0 a 100, donde los valores más altos indican una mejor CVRS.
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Línea de base, 52 semanas
|
|
Porcentaje de participantes sin empeoramiento en la puntuación de la evaluación global del médico (PGA) a las 52 semanas
Periodo de tiempo: 52 semanas
|
La Evaluación global del médico (PGA, por sus siglas en inglés) es una evaluación calificada por un médico de un solo elemento del nivel actual de actividad de la enfermedad del participante medido en una escala analítica visual continua de 100 mm con puntos de referencia de 0, 1, 2 y 3 de izquierda a derecha correspondientes a no actividad de la enfermedad de LES leve, moderada y grave.
Las puntuaciones se presentan de 0 a 100. Sin empeoramiento definido como un aumento de ≤ 0,30 puntos desde el valor inicial.
|
52 semanas
|
|
Número de participantes sin puntajes nuevos de actividad de la enfermedad en BILAG A y no más de uno en BILAG B en comparación con el valor inicial
Periodo de tiempo: Línea de base hasta las 52 semanas
|
El instrumento del Grupo de Evaluación del Lupus de las Islas Británicas (BILAG) evalúa la actividad global de la enfermedad en 9 dominios de sistemas de órganos.
Los brotes de BILAG se evalúan para cada uno de los 9 dominios de órganos utilizando las reglas del índice de brotes de BILAG2004; A es un brote severo y B es un brote moderado.
|
Línea de base hasta las 52 semanas
|
|
Porcentaje de participantes que lograron una respuesta según lo medido por SRI modificado sin BILAG A o no más de 1 brote de dominio de órgano BILAG B a las 52 semanas
Periodo de tiempo: 52 semanas
|
Porcentaje de participantes con una reducción de ≥ 5 puntos desde el inicio en la puntuación SELENA SLEDAI, y sin empeoramiento (aumento de < 0,30 puntos desde el inicio) en PGA, y sin BILAG A nuevo o no más de 1 nuevo brote de dominio de órgano BILAG B en comparación con el inicio . (Resultado primario modificado para usar brote de BILAG en lugar de puntuación de enfermedad de BILAG) SELENA SLEDAI se calcula a partir de 24 descriptores individuales en 9 sistemas de órganos; 0 indica enfermedad inactiva y la puntuación teórica máxima es 105. PGA es una escala analógica visual que se puntúa de 0 a 3 (0=ninguno, 1=leve, 2=moderado, 3=grave). El brote de BILAG se evalúa para cada uno de los 9 dominios de órganos; A es un brote severo y B es un brote moderado. Los participantes que no pudieron cumplir con los requisitos de medicamentos concomitantes permitidos se consideraron no respondedores, al igual que los participantes que abandonaron o a los que les faltaban los datos de la Semana 52. |
52 semanas
|
Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Publicaciones y enlaces útiles
La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.
Publicaciones Generales
- Hannon CW, McCourt C, Lima HC, Chen S, Bennett C. Interventions for cutaneous disease in systemic lupus erythematosus. Cochrane Database Syst Rev. 2021 Mar 9;3(3):CD007478. doi: 10.1002/14651858.CD007478.pub2.
- Toro-Dominguez D, Martorell-Marugan J, Martinez-Bueno M, Lopez-Dominguez R, Carnero-Montoro E, Barturen G, Goldman D, Petri M, Carmona-Saez P, Alarcon-Riquelme ME. Scoring personalized molecular portraits identify Systemic Lupus Erythematosus subtypes and predict individualized drug responses, symptomatology and disease progression. Brief Bioinform. 2022 Sep 20;23(5):bbac332. doi: 10.1093/bib/bbac332.
- Li Y, Higgs RE, Hoffman RW, Dow ER, Liu X, Petri M, Wallace DJ, Dorner T, Eastwood BJ, Miller BB, Liu Y. A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus. PLoS One. 2019 Dec 2;14(12):e0225651. doi: 10.1371/journal.pone.0225651. eCollection 2019.
- Kalunian KC, Urowitz MB, Isenberg D, Merrill JT, Petri M, Furie RA, Morgan-Cox MA, Taha R, Watts S, Silk M, Linnik MD. Clinical trial parameters that influence outcomes in lupus trials that use the systemic lupus erythematosus responder index. Rheumatology (Oxford). 2018 Jan 1;57(1):125-133. doi: 10.1093/rheumatology/kex368.
- Rovin BH, Dooley MA, Radhakrishnan J, Ginzler EM, Forrester TD, Anderson PW. The impact of tabalumab on the kidney in systemic lupus erythematosus: results from two phase 3 randomized, clinical trials. Lupus. 2016 Dec;25(14):1597-1601. doi: 10.1177/0961203316650734. Epub 2016 May 24.
- Hoffman RW, Merrill JT, Alarcon-Riquelme MM, Petri M, Dow ER, Nantz E, Nisenbaum LK, Schroeder KM, Komocsar WJ, Perumal NB, Linnik MD, Airey DC, Liu Y, Rocha GV, Higgs RE. Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab. Arthritis Rheumatol. 2017 Mar;69(3):643-654. doi: 10.1002/art.39950.
- Merrill JT, van Vollenhoven RF, Buyon JP, Furie RA, Stohl W, Morgan-Cox M, Dickson C, Anderson PW, Lee C, Berclaz PY, Dorner T. Efficacy and safety of subcutaneous tabalumab, a monoclonal antibody to B-cell activating factor, in patients with systemic lupus erythematosus: results from ILLUMINATE-2, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study. Ann Rheum Dis. 2016 Feb;75(2):332-40. doi: 10.1136/annrheumdis-2015-207654. Epub 2015 Aug 20.
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio
1 de enero de 2011
Finalización primaria (ACTUAL)
1 de agosto de 2014
Finalización del estudio (ACTUAL)
1 de marzo de 2015
Fechas de registro del estudio
Enviado por primera vez
17 de septiembre de 2010
Primero enviado que cumplió con los criterios de control de calidad
17 de septiembre de 2010
Publicado por primera vez (ESTIMAR)
20 de septiembre de 2010
Actualizaciones de registros de estudio
Última actualización publicada (ACTUAL)
17 de julio de 2018
Última actualización enviada que cumplió con los criterios de control de calidad
18 de junio de 2018
Última verificación
1 de junio de 2018
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- 13653
- H9B-MC-BCDT (OTRO: Eli Lilly and Company)
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .