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The Effects of Yoga Practice on Exercise Capacity, Arterial Stiffness, Respiratory Function, Peripheral Muscle Strength, Posture and Quality of Life in Children With Cystic Fibrosis

5 de noviembre de 2026 actualizado por: Naciye Vardar-Yagli, Hacettepe University

The aim of this study is to investigate the effects of exercise training applied through telerehabilitation on exercise capacity, peripheral and respiratory muscle strength, arterial stiffness, posture and quality of life in children with cystic fibrosis.

Descripción general del estudio

Estado

Reclutamiento

Condiciones

Intervención / Tratamiento

Descripción detallada

The most common problems in patients with cystic fibrosis (CF) are increased bronchial secretions, reduced exercise tolerance and shortness of breath.

Exercise capacity is limited due to muscle dysfunction, inflammation and progressive respiratory disease. Cardiovascular complications are one of the long-term complications of CF. Increased arterial stiffness is an indicator of elevated cardiovascular risk. It has been shown that patients with CF have increased arterial stiffness compared to their healthy peers.

Exercise training has a positive effect on exercise capacity, respiratory function and quality of life in patients with CF. Studies have shown that exercise training applied using the telerehabilitation method increases exercise capacity and improves peripheral muscle function in patients with CF. Peripheral muscle function, functional capacity, arterial stiffness and posture have been assessed in patients with CF. Furthermore, studies have been performed on patients with CF involving exercise training via telerehabilitation.In addition, various studies have shown that yoga and aerobic exercise training have positive effects on arterial stiffness. Although there are only a few studies involving patients with CF who practise yoga, no study has been found that assesses the effects of yoga practise via telerehabilitation on exercise capacity, peripheral and respiratory muscle function, and arterial stiffness.The purpose of this study is to examine the effects of exercise training using telerehabilitation on exercise capacity, peripheral and respiratory muscle strength, arterial stiffness, posture and quality of life in children with CF.

Children were randomly assigned to three groups: The first group will receive online aerobic exercise training and yoga sessions. The second group will receive only aerobic exercise training.The third group will be informed about the importance of physical activity and will be given recommendations for physical activity. Participants' respiratory function, exercise capacity, arterial stiffness parameters, peripheral muscle function, posture and quality of life questionnaire will be evaluated initially and following an 8-week exercise programme.

Tipo de estudio

Intervencionista

Inscripción (Estimado)

36

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Estudio Contacto

  • Nombre: Naciye Vardar-Yagli, PhD
  • Número de teléfono: +903123051576 ext 129
  • Correo electrónico: naciyevardar@yahoo.com

Ubicaciones de estudio

  • Turquía (Türkiye)
      • Ankara, Turquía (Türkiye), 06100
        • Reclutamiento
        • Hacettepe University
        • Contacto:

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

8 años a 18 años (Niño, Adulto)

Acepta Voluntarios Saludables

No

Géneros elegibles para el estudio

Todos

Descripción

Inclusion Criteria:

  • Patients aged 8-18 years with a diagnosis of cystic fibrosis (CF)
  • Access to online exercise training
  • Percent predicted of forced expiratory volume at one second (FEV1) > 40% in pulmonary function test

Exclusion Criteria:

  • Being diagnosed with acute pulmonary exacerbation at the time of study and /or within the last month.
  • Being physically or perceptually competent to exercise
  • Patients with allergic bronchopulmonary aspergillosis who were treated with systemic steroid therapy

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Tratamiento
  • Asignación: Aleatorizado
  • Modelo Intervencionista: Asignación paralela
  • Enmascaramiento: Único

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Experimental: Combined Group

aerobic exercise training and yoga sessions in patients with cystic fibrosis
Otro: aerobic exercises + yoga

Patients will be performed online in groups of 3-4 participants supervised aerobic exercises and yoga sessions. Aerobic exercises will be applied for 8 weeks, for 30-45 minutes, at 65-75% of the maximum heart rate, 3 days a week, on the days when yoga sessions are not performed. The yoga sessions will consist of 30-40-minute sessions, with three sessions per week for eight weeks. The yoga sessions will consist of three core components - asana (postures), pranayama (breathing) and meditation (focus).
Experimental: aerobic group

only aerobic exercises in patients with cystic fibrosis
Otro: aerobic exercises

Patients will be performed online in groups of 3-4 participants supervised only aerobic exercises Aerobic exercises will be applied for 8 weeks, for 30-45 minutes, at 65-75% of the maximum heart rate, 3 days a week.
Experimental: control group

physical activity recommendations in patients with cystic fibrosis
Otro: Physical activity recommendations

Patients will be informed of the benefits of physical activity and appropriate physical activity recommendations will be provided.

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
six minute walk test
Periodo de tiempo: before the exercise training

the distance reached in the six-minute walk test
before the exercise training
six minute walk test
Periodo de tiempo: eigth week

the distance reached in the six-minute walk test
eigth week

Medidas de resultado secundarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Arterial stiffness
Periodo de tiempo: before the exercise training

Arterial stiffness will be assessed non-invasively using the Mobil-O-GRAPH (I.E.M., Stolberg, Germany).
before the exercise training
Arterial stiffness
Periodo de tiempo: eight week

Arterial stiffness will be assessed non-invasively using the Mobil-O-GRAPH (I.E.M., Stolberg, Germany).
eight week
Respiratory muscle strength
Periodo de tiempo: before the exercise training

Respiratory muscle strength will be evaluated using mouth pressure device
before the exercise training
Respiratory muscle strength
Periodo de tiempo: eight week

Respiratory muscle strength will be evaluated using mouth pressure device
eight week
respiratory muscle endurance
Periodo de tiempo: before the exercise training

Respiratory muscle endurance will be assessed using constant load test
before the exercise training
respiratory muscle endurance
Periodo de tiempo: eight week

Respiratory muscle endurance will be assessed using constant load test
eight week
Pulmonary functions-FVC
Periodo de tiempo: before the exercise training

Forced vital capacity (FVC)
before the exercise training
Pulmonary functions-FVC
Periodo de tiempo: eight week

Forced vital capacity (FVC)
eight week
Pulmonary functions-FEV1
Periodo de tiempo: before the exercise training

Forced expiratory volume in the first second (FEV1)
before the exercise training
Pulmonary functions-FEV1
Periodo de tiempo: eigth week

Forced expiratory volume in the first second (FEV1)
eigth week
Pulmonary functions-FEV1/FVC
Periodo de tiempo: before the exercise training

FEV1/ FVC
before the exercise training
Pulmonary functions-FEV1/FVC
Periodo de tiempo: eight week

FEV1/ FVC
eight week
Pulmonary functions-FEF25-75
Periodo de tiempo: before the exercise training

Forced mid-expiratory flow (FEF25-75)
before the exercise training
Pulmonary functions-FEF25-75
Periodo de tiempo: eigth week

Forced mid-expiratory flow (FEF25-75)
eigth week
Peripheral muscle strength
Periodo de tiempo: before the exercise training

Peripheral muscle strength will be assessed using dynamometer
before the exercise training
Peripheral muscle strength
Periodo de tiempo: eigth week

Peripheral muscle strength will be assessed using dynamometer
eigth week
1 minute sit to stand test (STS) repetitions
Periodo de tiempo: before the exercise training

number of sit to stand for one minute is recorded
before the exercise training
1 minute sit to stand test (STS) repetitions
Periodo de tiempo: eight week

number of sit to stand for one minute is recorded
eight week
posture
Periodo de tiempo: before the exercise training

Posture will be assessed using Corbin Postural Assessment scale. Lateral and posterior views will be assessed (0 = absent,1 = mild, 2 = moderate, 3 = severe) and posture score will be determined as excellent(0-2), very good (3-4), good (5-7), fair (8-11)and poor (>12).
before the exercise training
posture
Periodo de tiempo: eigth week

Posture will be assessed using Corbin Postural Assessment scale. Lateral and posterior views will be assessed (0 = absent,1 = mild, 2 = moderate, 3 = severe) and posture score will be determined as excellent(0-2), very good (3-4), good (5-7), fair (8-11)and poor (>12).
eigth week
Quality of life assessment
Periodo de tiempo: before the exercise training

Quality of life will be assessed using the Cystic Fibrosis Questionnaire-Revised .The Cystic Fibrosis Questionnaire-Revised is a disease-specific health-related quality of life measure for children, adolescents with cystic fibrosis (CF). The questionnaire evaluate physical functioning, emotional functioning, social functioning, body image, eating disorders, treatment,respiratory symptoms and digestive symptoms. Score range is 0-100. Higher scores indicating higher health-related qualityof life.
before the exercise training
Quality of life assessment
Periodo de tiempo: eigth week

Quality of life will be assessed using the Cystic Fibrosis Questionnaire-Revised .The Cystic Fibrosis Questionnaire-Revised is a disease-specific health-related quality of life measure for children, adolescents with cystic fibrosis (CF). The questionnaire evaluate physical functioning, emotional functioning, social functioning, body image, eating disorders, treatment,respiratory symptoms and digestive symptoms. Score range is 0-100. Higher scores indicating higher health-related quality of life.
eigth week

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Patrocinador

Hacettepe University

Investigadores

  • Investigador principal: Naciye Vardar-Yagli, PhD, Hacettepe University

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio (Actual)

10 de julio de 2025

Finalización primaria (Estimado)

1 de julio de 2027

Finalización del estudio (Estimado)

1 de julio de 2027

Fechas de registro del estudio

Enviado por primera vez

5 de noviembre de 2026

Primero enviado que cumplió con los criterios de control de calidad

5 de noviembre de 2026

Publicado por primera vez (Actual)

12 de noviembre de 2026

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

12 de noviembre de 2026

Última actualización enviada que cumplió con los criterios de control de calidad

5 de noviembre de 2026

Última verificación

1 de octubre de 2026

Más información

Términos relacionados con este estudio

Palabras clave

Términos MeSH relevantes adicionales

Otros números de identificación del estudio

  • FTREK25/92

Plan de datos de participantes individuales (IPD)

¿Planea compartir datos de participantes individuales (IPD)?

NO

Información sobre medicamentos y dispositivos, documentos del estudio

Estudia un producto farmacéutico regulado por la FDA de EE. UU.

No

Estudia un producto de dispositivo regulado por la FDA de EE. UU.

No

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

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