Comparison of Bacterial Contamination Rates Between Isolation and Non-isolation Rooms
1 juin 2015 mis à jour par: Michael Sweet, West Virginia University
Comparison of Contamination Rates of Medication Storage Cabinets Between Isolation and Non-isolation Rooms With Methicillin-resistant Staphylococcus Aureus (MRSA)
This study is to determine if medication cabinets located outside of isolation rooms in hospitals and their contents, particularly medications and the delivery folders are at a higher risk of having harmful bacteria on them.
Aperçu de l'étude
Statut
Complété
Les conditions
Description détaillée
Studies show high touch areas maybe contaminated with organisms such as Methicillin-resistant Staphylococcus aureus(MRSA) and vancomycin-resistant enterococci. MRSA can live on hospital surfaces for 9-14 days. Patients in rooms that were previously MRSA isolation rooms are at higher risk for developing a hospital-acquired infection.
This study is to determine if medication cabinets located outside of MRSA isolation rooms and their contents, particularly medications and the pharmacy delivery folders are at a higher risk of having MRSA colonization on them. This study will use conventional methods to determine if MRSA colonization is present and compare results between non-isolation and isolation rooms. This will evaluate if alternate measures for the reduction of MRSA colonization are needed for the MRSA isolation rooms in regards to medication delivery and storage.
Type d'étude
Observationnel
Inscription (Réel)
400
Contacts et emplacements
Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.
Lieux d'étude
-
-
West Virginia
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Morgantown, West Virginia, États-Unis, 26506
- West Virginia University Hospitals
-
-
Critères de participation
Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.
Critère d'éligibilité
Âges éligibles pour étudier
- Enfant
- Adulte
- Adulte plus âgé
Accepte les volontaires sains
Oui
Sexes éligibles pour l'étude
Tout
Méthode d'échantillonnage
Échantillon de probabilité
Population étudiée
Inaptients at an academic medical center
La description
Inclusion Criteria:
- Patient rooms with isolation status for MRSA
- Patient rooms without isolation status for MRSA for 14 days
Exclusion Criteria:
- Rooms without medication cabinets directly outside the room
Plan d'étude
Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.
Comment l'étude est-elle conçue ?
Détails de conception
Cohortes et interventions
Groupe / Cohorte |
|---|
|
Isolation Rooms for MRSA
Rooms that currently have a patient in them that are in isolation status due to MRSA
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Non-isolation rooms
Rooms that have not been occupied by a patient in isolation due to MRSA for 14 days
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Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Presence of MRSA colonization
Délai: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
Individual colonies will be removed from the plate with an inoculation loop, then streaked onto a second sheep blood agar plate.
The second plates will be incubated for 48 hours.
The colonies will then be run through standard identification tests to determine if the colonies are MRSA or not.
A comparison will be made between non-isolation and isolation rooms.
|
Hospital stay, an expected average of 14 days
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Quantification of MRSA colonization
Délai: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
A comparison between the sites of swabbing will be performed.
|
Hospital stay, an expected average of 14 days
|
Autres mesures de résultats
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Presence of other bacterial colonization
Délai: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
Individual colonies will be removed from the plate with an inoculation loop, then streaked onto a second sheep blood agar plate.
The second plates will be incubated for 48 hours.
The colonies will be categorized as gram negative, gram positive catalase negative, Gram positive coagulase negative Staphylococcus species or methicillin-sensitive Staphylococcus aureus.
This will serve as a baseline epidemiology of the hospital and generate other possible hypotheses.
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Hospital stay, an expected average of 14 days
|
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Correlation between MRSA and active infection or colonization of patient
Délai: Hospital stay, an expected average of 14 days
|
The patient from the same time frame in the rooms sampled and positive for MRSA colonization will be reviewed to determine if they had active infection or were previously colonized.
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Hospital stay, an expected average of 14 days
|
|
Correlation between colonization of other positive organisms and active infection or colonization of patient
Délai: Hospital stay, an expected average of 14 days
|
The patient from the same time frame in the rooms sampled and positive for non-MRSA colonization will be reviewed to determine if they had active infection or were previously colonized.
|
Hospital stay, an expected average of 14 days
|
Collaborateurs et enquêteurs
C'est ici que vous trouverez les personnes et les organisations impliquées dans cette étude.
Parrainer
Publications et liens utiles
La personne responsable de la saisie des informations sur l'étude fournit volontairement ces publications. Il peut s'agir de tout ce qui concerne l'étude.
Publications générales
- Bures S, Fishbain JT, Uyehara CF, Parker JM, Berg BW. Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit. Am J Infect Control. 2000 Dec;28(6):465-71. doi: 10.1067/mic.2000.107267.
- Sexton T, Clarke P, O'Neill E, Dillane T, Humphreys H. Environmental reservoirs of methicillin-resistant Staphylococcus aureus in isolation rooms: correlation with patient isolates and implications for hospital hygiene. J Hosp Infect. 2006 Feb;62(2):187-94. doi: 10.1016/j.jhin.2005.07.017. Epub 2005 Nov 14.
- Oie S, Hosokawa I, Kamiya A. Contamination of room door handles by methicillin-sensitive/methicillin-resistant Staphylococcus aureus. J Hosp Infect. 2002 Jun;51(2):140-3. doi: 10.1053/jhin.2002.1221.
- Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med. 2006 Oct 9;166(18):1945-51. doi: 10.1001/archinte.166.18.1945.
- Huang R, Mehta S, Weed D, Price CS. Methicillin-resistant Staphylococcus aureus survival on hospital fomites. Infect Control Hosp Epidemiol. 2006 Nov;27(11):1267-9. doi: 10.1086/507965. Epub 2006 Sep 28.
Dates d'enregistrement des études
Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.
Dates principales de l'étude
Début de l'étude
1 août 2012
Achèvement primaire (Réel)
1 juin 2013
Achèvement de l'étude (Réel)
1 juin 2013
Dates d'inscription aux études
Première soumission
16 août 2012
Première soumission répondant aux critères de contrôle qualité
20 août 2012
Première publication (Estimation)
23 août 2012
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Estimation)
2 juin 2015
Dernière mise à jour soumise répondant aux critères de contrôle qualité
1 juin 2015
Dernière vérification
1 juin 2015
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- WVU-00010
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