- ICH GCP
- Registr klinických studií v USA
- Klinická studie NCT01671358
Comparison of Bacterial Contamination Rates Between Isolation and Non-isolation Rooms
Comparison of Contamination Rates of Medication Storage Cabinets Between Isolation and Non-isolation Rooms With Methicillin-resistant Staphylococcus Aureus (MRSA)
Přehled studie
Postavení
Detailní popis
Studies show high touch areas maybe contaminated with organisms such as Methicillin-resistant Staphylococcus aureus(MRSA) and vancomycin-resistant enterococci. MRSA can live on hospital surfaces for 9-14 days. Patients in rooms that were previously MRSA isolation rooms are at higher risk for developing a hospital-acquired infection.
This study is to determine if medication cabinets located outside of MRSA isolation rooms and their contents, particularly medications and the pharmacy delivery folders are at a higher risk of having MRSA colonization on them. This study will use conventional methods to determine if MRSA colonization is present and compare results between non-isolation and isolation rooms. This will evaluate if alternate measures for the reduction of MRSA colonization are needed for the MRSA isolation rooms in regards to medication delivery and storage.
Typ studie
Zápis (Aktuální)
Kontakty a umístění
Studijní místa
-
-
West Virginia
-
Morgantown, West Virginia, Spojené státy, 26506
- West Virginia University Hospitals
-
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Kritéria účasti
Kritéria způsobilosti
Věk způsobilý ke studiu
- Dítě
- Dospělý
- Starší dospělý
Přijímá zdravé dobrovolníky
Pohlaví způsobilá ke studiu
Metoda odběru vzorků
Studijní populace
Popis
Inclusion Criteria:
- Patient rooms with isolation status for MRSA
- Patient rooms without isolation status for MRSA for 14 days
Exclusion Criteria:
- Rooms without medication cabinets directly outside the room
Studijní plán
Jak je studie koncipována?
Detaily designu
Kohorty a intervence
Skupina / kohorta |
---|
Isolation Rooms for MRSA
Rooms that currently have a patient in them that are in isolation status due to MRSA
|
Non-isolation rooms
Rooms that have not been occupied by a patient in isolation due to MRSA for 14 days
|
Co je měření studie?
Primární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
---|---|---|
Presence of MRSA colonization
Časové okno: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
Individual colonies will be removed from the plate with an inoculation loop, then streaked onto a second sheep blood agar plate.
The second plates will be incubated for 48 hours.
The colonies will then be run through standard identification tests to determine if the colonies are MRSA or not.
A comparison will be made between non-isolation and isolation rooms.
|
Hospital stay, an expected average of 14 days
|
Sekundární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
---|---|---|
Quantification of MRSA colonization
Časové okno: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
A comparison between the sites of swabbing will be performed.
|
Hospital stay, an expected average of 14 days
|
Další výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
---|---|---|
Presence of other bacterial colonization
Časové okno: Hospital stay, an expected average of 14 days
|
Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication).
A Semi-quantitative sampling technique will be used to collect the samples.
A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas.
The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants.
The plates will be incubated for 48 hours.
The number of quadrants with growth will be identified.
Individual colonies will be removed from the plate with an inoculation loop, then streaked onto a second sheep blood agar plate.
The second plates will be incubated for 48 hours.
The colonies will be categorized as gram negative, gram positive catalase negative, Gram positive coagulase negative Staphylococcus species or methicillin-sensitive Staphylococcus aureus.
This will serve as a baseline epidemiology of the hospital and generate other possible hypotheses.
|
Hospital stay, an expected average of 14 days
|
Correlation between MRSA and active infection or colonization of patient
Časové okno: Hospital stay, an expected average of 14 days
|
The patient from the same time frame in the rooms sampled and positive for MRSA colonization will be reviewed to determine if they had active infection or were previously colonized.
|
Hospital stay, an expected average of 14 days
|
Correlation between colonization of other positive organisms and active infection or colonization of patient
Časové okno: Hospital stay, an expected average of 14 days
|
The patient from the same time frame in the rooms sampled and positive for non-MRSA colonization will be reviewed to determine if they had active infection or were previously colonized.
|
Hospital stay, an expected average of 14 days
|
Spolupracovníci a vyšetřovatelé
Sponzor
Publikace a užitečné odkazy
Obecné publikace
- Bures S, Fishbain JT, Uyehara CF, Parker JM, Berg BW. Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit. Am J Infect Control. 2000 Dec;28(6):465-71. doi: 10.1067/mic.2000.107267.
- Sexton T, Clarke P, O'Neill E, Dillane T, Humphreys H. Environmental reservoirs of methicillin-resistant Staphylococcus aureus in isolation rooms: correlation with patient isolates and implications for hospital hygiene. J Hosp Infect. 2006 Feb;62(2):187-94. doi: 10.1016/j.jhin.2005.07.017. Epub 2005 Nov 14.
- Oie S, Hosokawa I, Kamiya A. Contamination of room door handles by methicillin-sensitive/methicillin-resistant Staphylococcus aureus. J Hosp Infect. 2002 Jun;51(2):140-3. doi: 10.1053/jhin.2002.1221.
- Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med. 2006 Oct 9;166(18):1945-51. doi: 10.1001/archinte.166.18.1945.
- Huang R, Mehta S, Weed D, Price CS. Methicillin-resistant Staphylococcus aureus survival on hospital fomites. Infect Control Hosp Epidemiol. 2006 Nov;27(11):1267-9. doi: 10.1086/507965. Epub 2006 Sep 28.
Termíny studijních záznamů
Hlavní termíny studia
Začátek studia
Primární dokončení (Aktuální)
Dokončení studie (Aktuální)
Termíny zápisu do studia
První předloženo
První předloženo, které splnilo kritéria kontroly kvality
První zveřejněno (Odhad)
Aktualizace studijních záznamů
Poslední zveřejněná aktualizace (Odhad)
Odeslaná poslední aktualizace, která splnila kritéria kontroly kvality
Naposledy ověřeno
Více informací
Termíny související s touto studií
Klíčová slova
Další relevantní podmínky MeSH
Další identifikační čísla studie
- WVU-00010
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