Study About Lymphocytes Change During Menstrual Cycle in Women of Child-bearing Age
The investigators are going to select the normal child-bearing period women as the study subjects and draw their peripheral blood to observe and analyze the change of quantity and percentage of lymphocyte subsets along with the change of menstrual cycle.
Recording their BMI\menstrual history\and childbearing history, the investigators would select 300 healthy women in 6 different age groups which are aged 20-24, aged 25-29, aged 30-34, aged35-39, aged 40-44 and aged 45-49, then draw 1-2 ml blood form their peripheral vein (adding EDTA for anti-coagulation). The investigators are going to perform routine examination on the blood samples and detect T\B\NK lymphocyte through flow cytometry (FCM), thus calculating the absolute number of every species of lymphocyte. The investigators make assessment for the cellular immune function of the women during child-bearing period via comparing distinction in percentage and absolute number of every lymphocyte subset among reproductive-age women in different ages.
Aperçu de l'étude
Statut
Les conditions
Type d'étude
Inscription (Anticipé)
Contacts et emplacements
Lieux d'étude
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Shanghai, Chine, 200051
- Recrutement
- Shanghai first Maternity and Infant health hospital, Tong Ji University
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Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
Méthode d'échantillonnage
Population étudiée
La description
Inclusion Criteria:
- Women aged 20-49;
- Having a regular menstrual cycle of which the menstrual period is between day 3-7, and the period between day 25-35;
- Excluding internal and surgical disease (after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine routine).
Exclusion Criteria:
- Having experienced severe allergies, trauma history and/or operation history within 3 months;
- With a history of mental illness and/or family history of mental illness;
- Limb disabled;
- Taking medicine within one month;
- Suffering major events or having mood swings.
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
Cohortes et interventions
Groupe / Cohorte |
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observational group
Observational Study about Lymphocytes Change during Menstrual Cycle in Women of Child-bearing Age
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Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Délai |
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the percentage of lymphocyte subsets
Délai: through study completion, an average of 1 year
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through study completion, an average of 1 year
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Collaborateurs et enquêteurs
Les enquêteurs
- Chaise d'étude: Tao Duan, Shanghai first maternity and infant hospital
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude
Achèvement primaire (Réel)
Achèvement de l'étude (Anticipé)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Estimation)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Autres numéros d'identification d'étude
- ShanghaiFMIH-RI
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