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Juçara (Euterpe Edulis Martius) Supplementation Effect in Muscle Protection, Performance and Soreness in Lower Limbs After Exercise-Induced Muscle Damage

7 maggio 2026 aggiornato da: Fábio Juner Lanferdini, Universidade Federal de Santa Maria

Juçara (Euterpe Edulis Martius) Supplementation Effect in Muscle Protection, Performance and Soreness in Lower Limbs After Exercise-Induced Muscle Damage: A Six-Week Randomized, Triple-Blind, Placebo-Controlled Clinical Trial

The purpose of this study is to find out if taking a natural supplement made from the Juçara fruit (a Brazilian berry rich in antioxidants called anthocyanins) can help the body recover faster after damage caused by exercise. Researchers want to see if Juçara can reduce muscle soreness and help muscles regain their strength and quality more quickly compared to a placebo (a "dummy" pill with no active ingredients).

What happens during the study? The study included 24 healthy, active men. It was a "crossover" study, meaning every participant tried both the Juçara supplement and the placebo at different times.

Supplement Phase: Participants took 12 capsules a day for 7 days.

Muscle Damage Test: To cause temporary muscle damage, participants performed a specific jumping protocol (100 maximal jumps).

Recovery Monitoring: Researchers tracked the participants for 72 hours after the jumps to measure:

How high they could jump (strength/performance).

Muscle soreness (using a pain scale).

Muscle "quality" and stiffness (using ultrasound imaging).

Wait Period: After the first phase, participants waited 14 days (washout) before switching to the other supplement to repeat the process.

Panoramica dello studio

Stato

Completato

Condizioni

Juçara Supplementatios After Muscle Damage

Intervento / Trattamento

Tipo di studio

Interventistico

Iscrizione (Effettivo)

Fase

Non applicabile

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Luoghi di studio

Brasile
- Rio Grande do Sul
  - Santa Maria, Rio Grande do Sul, Brasile, 97105900
    - Centro de Educação Física e Desportos

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

Adulto

Accetta volontari sani

Descrizione

Inclusion Criteria:

Males
Aged 18-40 years
Physically active, defined as performing at least three exercise sessions per week according to IPAQ questionnaire
No history at lower-limb within the previous six months
No medical restrictions for maximal exercise testing
No allergy to red fruits
No physical, cognitive and/or psychological limitations affecting the execution or understanding of the protocol
No history of lower-limb surgery
No use nutritional supplements within 30 days prior to study initiation
Abstention from caffeine, cacao, yerba mate tea, and soft drinks during the study protocol.

Exclusion Criteria:

Individuals younger than 18 or older than 40 years
Not physically active, defined as performing fewer than three exercise sessions per week according to IPAQ questionnaire
Presence of history at lower-limb injury within the previous six months
Presence of medical restrictions for maximal exercise testing
Known allergy to red fruits
Presence of physical, cognitive and/or psychological limitations affecting the execution or understanding of the protocol
History of lower-limb surgery
Use of nutritional supplements within 30 days prior to study initiation
Inability to abstain from caffeine, cacao, yerba mate tea, and soft drinks during the study protocol

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

Scopo principale: Altro
Assegnazione: Randomizzato
Modello interventistico: Assegnazione incrociata
Mascheramento: Quadruplicare

Numero di armi

Armi e interventi

Gruppo di partecipanti / Arm	Intervento / Trattamento
Sperimentale: Juçara group The sample consisted of 24 healthy, physically active men with any kind of experience in any physical exercise modality. Eligibility criteria were as follows: (1) male, aged 18-40 years; (2) physically active, defined as performing at least three exercise sessions per week according to IPAQ questionnaire; (3) no history at lower-limb within the previous six months; (4) no medical restrictions for maximal exercise testing; (5) no allergy to red fruits; (6) no physical, cognitive and/or psychological limitations affecting the execution or understanding of the protocol; (7) no history of lower-limb surgery; (8) no use nutritional supplements within 30 days prior to study initiation; and (9) abstention from caffeine, cacao, yerba mate tea, and soft drinks during the study protocol.	Integratore alimentare: Juçara Total of 11 separate occasions under the Juçara condition. A familiarization session of CMJ and EIMD protocol (10 sets of CMJ repetitions with 1-minute rest between sets) was performed, followed by a 14-day washout period. During this visit, volunteers' descriptive data were assessed. On day 1 of this condition (72h pre EIMD), body mass was obtained, and participants received the supplementation (Juçara) to be consumed for 7 days (one capsule every 12 h). On day 2, the CSA from QUAD and HAMS, elastography from vastus lateralis (VL) and biceps femoris long head (BFlh) of the dominant limb, and the CMJ performance were assessed. After that, participants performed the EIMD protocol. Follow-up assessments were conducted at 24 h (day 3), 48 h (day 4), and 72 h (day 5) post-EIMD, repeating the same measurements. A 14-day washout period separated the two interventions.
Comparatore placebo: Placebo Group The sample consisted of 24 healthy, physically active men with any kind of experience in any physical exercise modality. Eligibility criteria were as follows: (1) male, aged 18-40 years; (2) physically active, defined as performing at least three exercise sessions per week according to IPAQ questionnaire; (3) no history at lower-limb within the previous six months; (4) no medical restrictions for maximal exercise testing; (5) no allergy to red fruits; (6) no physical, cognitive and/or psychological limitations affecting the execution or understanding of the protocol; (7) no history of lower-limb surgery; (8) no use nutritional supplements within 30 days prior to study initiation; and (9) abstention from caffeine, cacao, yerba mate tea, and soft drinks during the study protocol.	Integratore alimentare: Placebo group Total of 11 separate occasions under the placebo condition. A familiarization session of CMJ and EIMD protocol (10 sets of CMJ repetitions with 1-minute rest between sets) was performed, followed by a 14-day washout period. During this visit, volunteers' descriptive data were assessed. On day 1 of this condition (72h pre EIMD), body mass was obtained, and participants received the supplementation (placebo) to be consumed for 7 days (one capsule every 12 h). On day 2, the CSA from QUAD and HAMS, elastography from vastus lateralis (VL) and biceps femoris long head (BFlh) of the dominant limb, and the CMJ performance were assessed. After that, participants performed the EIMD protocol. Follow-up assessments were conducted at 24 h (day 3), 48 h (day 4), and 72 h (day 5) post-EIMD, repeating the same measurements. A 14-day washout period separated the two interventions.

Gruppo di partecipanti / Arm

Intervento / Trattamento

Sperimentale: Juçara group

The sample consisted of 24 healthy, physically active men with any kind of experience in any physical exercise modality. Eligibility criteria were as follows: (1) male, aged 18-40 years; (2) physically active, defined as performing at least three exercise sessions per week according to IPAQ questionnaire; (3) no history at lower-limb within the previous six months; (4) no medical restrictions for maximal exercise testing; (5) no allergy to red fruits; (6) no physical, cognitive and/or psychological limitations affecting the execution or understanding of the protocol; (7) no history of lower-limb surgery; (8) no use nutritional supplements within 30 days prior to study initiation; and (9) abstention from caffeine, cacao, yerba mate tea, and soft drinks during the study protocol.

Integratore alimentare: Juçara

Total of 11 separate occasions under the Juçara condition. A familiarization session of CMJ and EIMD protocol (10 sets of CMJ repetitions with 1-minute rest between sets) was performed, followed by a 14-day washout period. During this visit, volunteers' descriptive data were assessed. On day 1 of this condition (72h pre EIMD), body mass was obtained, and participants received the supplementation (Juçara) to be consumed for 7 days (one capsule every 12 h). On day 2, the CSA from QUAD and HAMS, elastography from vastus lateralis (VL) and biceps femoris long head (BFlh) of the dominant limb, and the CMJ performance were assessed. After that, participants performed the EIMD protocol. Follow-up assessments were conducted at 24 h (day 3), 48 h (day 4), and 72 h (day 5) post-EIMD, repeating the same measurements. A 14-day washout period separated the two interventions.

Comparatore placebo: Placebo Group

Integratore alimentare: Placebo group

Total of 11 separate occasions under the placebo condition. A familiarization session of CMJ and EIMD protocol (10 sets of CMJ repetitions with 1-minute rest between sets) was performed, followed by a 14-day washout period. During this visit, volunteers' descriptive data were assessed. On day 1 of this condition (72h pre EIMD), body mass was obtained, and participants received the supplementation (placebo) to be consumed for 7 days (one capsule every 12 h). On day 2, the CSA from QUAD and HAMS, elastography from vastus lateralis (VL) and biceps femoris long head (BFlh) of the dominant limb, and the CMJ performance were assessed. After that, participants performed the EIMD protocol. Follow-up assessments were conducted at 24 h (day 3), 48 h (day 4), and 72 h (day 5) post-EIMD, repeating the same measurements. A 14-day washout period separated the two interventions.

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato	Misura Descrizione	Lasso di tempo
Countermovement Jump Height Lasso di tempo: From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.	Countermovement Jump (CMJ) hieght will be measured to assess using two force plates (AMTI OR6-6-2000; 1000 Hz). Measurements will be obtained at Baseline (Pre), and at 24, 48, and 72 hours following the exercise induced muscle damage (EIMD) protocol. Data will be expressed in centimeters (cm). Jump height will be calculated using take-off velocity and projectile motion principles.	From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.
Contermovement jump power Lasso di tempo: From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.	Countermovement Jump (CMJ) power will be evaluated using two force plates (AMTI OR6-6-2000; 1000 Hz). Peak power will be calculated based on the jump flight time or force-time curve. Assessments will be performed at Baseline (Pre), 24h, 48h, and 72h post exercise induced muscle damage. Data will be expressed in Watts (W). Power during the concentric phase (i.e., the propulsive phase; interval between the onset of propulsion and take-off) will be calculated by multiplying force by velocity.	From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.
Quadriceps and hamstrings Echointensity Lasso di tempo: From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.	Quadriceps and Hamstrings muscle echointensity will be assessed using ultrasonography to evaluate muscle damage. Images will be analyzed through gray-scale histogram analysis using ImageJ software. Assessments will be performed at Baseline (Pre-exercise), and at 24 hours, 48 hours, and 72 hours following the exercise-induced muscle damage (EIMD) protocol. Data will be expressed in arbitrary units (AU).	From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.
Quadriceps and Hamstrings Cross-Sectional Area Lasso di tempo: From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol	Muscle Cross-Sectional Area from Quadriceps and Hamstrings will be assessed using an ultrasound with extended field of view mode at 50% of limb length. Quadriceps and Hamstrings Cros-Sectional areas will be expressed in cm².	From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol
Vastus Lateralis and Biceps Femoris Long Head stiffness Lasso di tempo: From pre Exercise Muscle Damage Protocol to Post-72h Exercise Induced Muscle Damage protocol.	Vastus Lateralis and Biceps Femoris Long Head muscle stiffness will be assessed using Shear Wave Elastography mode from an ultrasound. Muscle stiffness will be expressed in kilopascal (kPa).	From pre Exercise Muscle Damage Protocol to Post-72h Exercise Induced Muscle Damage protocol.
Quadriceps and Hamstrings muscle soreness Lasso di tempo: From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.	Muscle soreness of the quadriceps will be assessed using a Visual Analogue Scale (VAS). Measurements will be obtained at Baseline (Pre-exercise), Immediately Post-exercise, 24 hours, 48 hours, and 72 hours following the Exercise Induced Muscle Damage (EIMD) protocol. Data will be expressed on a scale from 0 (no soreness) to 30 centimeters (worst possible soreness).	From pre Exercise Induced Muscle Damage protocol to Post-72h Exercise Induced Muscle Damage protocol.

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

Universidade Federal de Santa Maria

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Effettivo)

3 giugno 2024

Completamento primario (Effettivo)

3 ottobre 2024

Completamento dello studio (Effettivo)

2 dicembre 2024

Date di iscrizione allo studio

Primo inviato

30 aprile 2026

Primo inviato che soddisfa i criteri di controllo qualità

7 maggio 2026

Primo Inserito (Effettivo)

13 maggio 2026

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)

13 maggio 2026

Ultimo aggiornamento inviato che soddisfa i criteri QC

7 maggio 2026

Ultimo verificato

1 maggio 2026

Maggiori informazioni

Termini relativi a questo studio

Parole chiave

Altri numeri di identificazione dello studio

6.753.984
UFSM (Altro identificatore: UFSM)

Informazioni su farmaci e dispositivi, documenti di studio

Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti

Studia un dispositivo regolamentato dalla FDA degli Stati Uniti

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

Juçara (Euterpe Edulis Martius) Supplementation Effect in Muscle Protection, Performance and Soreness in Lower Limbs After Exercise-Induced Muscle Damage