Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls
20 agosto 2026 aggiornato da: fatih bali, Istanbul Medipol University Hospital
A Multidimensional Physical Profile of Cervicogenic Headache: A Cross-Sectional Comparison With Nonspecific Neck Pain and Healthy Controls
The goal of this observational study is to compare physical findings across three adult groups. Cervicogenic headache (CGH) is a headache linked to a problem in the neck. Neck pain may affect posture, muscle function, grip strength, and sensitivity to pressure. Researchers do not know whether CGH has a distinct pattern of these findings.
The main questions are:
- Do posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity differ among the groups?
- Are any differences more closely associated with CGH than with neck pain?
Researchers will compare adults ages 25 through 60. One group will include people with CGH lasting at least three months. Another group will include people with neck pain lasting at least six months. People in the neck pain group will have no headaches. Healthy participants will have no neck pain or headaches.
Researchers will not provide treatment or change participants' usual care. Each participant will complete one study visit lasting about 15 minutes. Participants will:
- Answer short questions about their health and pain
- Stand while researchers measure their head and neck posture
- Squeeze a device that measures grip strength
- Complete brief tests of neck muscle stiffness and elasticity
- Tell researchers when applied pressure first becomes painful
Researchers will compare results across the three groups. The findings may guide future CGH assessment and treatment research.
Panoramica dello studio
Stato
Reclutamento
Condizioni
Tipo di studio
Osservativo
Iscrizione (Stimato)
135
Contatti e Sedi
Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.
Contatto studio
- Nome: Fatih Bali, PhD.
- Numero di telefono: +905323937689
- Email: fatihbali@hotmail.com
Luoghi di studio
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Sefaköy
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Istanbul, Sefaköy, Turchia (Türkiye), 34433
- Reclutamento
- Medipol Sefaköy Üniversite Hastanesi
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Contatto:
- Fatih Bali, PhD.
- Numero di telefono: +905323937689
- Email: fatihbali@hotmail.com
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Contatto:
- Email: fatihbali@hotmail.com
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Criteri di partecipazione
I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.
Criteri di ammissibilità
Età idonea allo studio
- Adulto
Accetta volontari sani
Sì
Metodo di campionamento
Campione non probabilistico
Popolazione di studio
The study population consists of adults aged 25-60 years recruited at the study site in Istanbul, Türkiye.
Participants are classified into three groups according to predefined clinical criteria.
The cervicogenic headache group includes individuals diagnosed by a physician according to the International Classification of Headache Disorders, 3rd edition.
The chronic nonspecific neck pain group includes individuals with neck pain lasting at least 6 months and no headache.
The healthy control group includes individuals without neck pain or headache.
Participants receive no study intervention and complete one questionnaire-based and instrument-based assessment session.
Descrizione
- Inclusion Criteria:
- Aged 25 to 60 years
- Able to provide written informed consent
- Meeting the criteria for one of the following groups:
- Cervicogenic headache: physician diagnosis according to the International Classification of Headache Disorders, 3rd edition, with symptoms lasting at least 3 months
- Chronic nonspecific neck pain: neck pain lasting at least 6 months without headache
- Healthy control: no neck pain or headache
Exclusion Criteria:
- Receipt of physiotherapy for headache or neck pain during the previous 6 months
- Diagnosis of a headache disorder other than cervicogenic headache, including migraine or tension-type headache, or a diagnosis of trigeminal neuralgia
- History of cervical spine surgery or significant cervical trauma
- Current or previous diagnosis of a tumor or cancer
- Serious cardiovascular, cerebrovascular, hematological, metabolic, neurological, or psychiatric disorder
- Rheumatoid arthritis
- Congenital cervical abnormality
- Cervical spondylolisthesis or cervical instability
- Active infection
- Temporomandibular joint dysfunction
- Dizziness or visual disturbance accompanying headache
- Any clinical red flag suggesting serious cervical pathology
- Pregnancy or breastfeeding
- Upper-extremity injury, surgery, or another condition affecting handgrip strength
- Serious musculoskeletal disorder affecting cervical posture or muscle measurements
- Inability to complete the questionnaire-based or instrument-based assessments
Piano di studio
Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.
Come è strutturato lo studio?
Dettagli di progettazione
Coorti e interventi
Gruppo / Coorte |
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Cervicogenic Headache Group
Adults aged 25-60 years with cervicogenic headache diagnosed by a physician according to the International Classification of Headache Disorders, 3rd edition (ICHD-3), and symptoms lasting at least 3 months.
Participants undergo one questionnaire-based and instrument-based assessment session.
No intervention is assigned.
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Chronic Nonspescific Neck Pain Group
Adults aged 25-60 years with chronic nonspecific neck pain lasting at least 6 months and no headache.
Participants undergo one questionnaire-based and instrument-based assessment session.
No intervention is assigned.
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Healthy Control Group
Adults aged 25-60 years with no neck pain or headaches.
Participants undergo one questionnaire-based and instrument-based assessment session.
No intervention is assigned.
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Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
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Bilateral Upper Trapezius Muscle Stiffness
Lasso di tempo: During the single assessment session at enrollment
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Upper trapezius muscle stiffness will be assessed bilaterally using the MyotonPRO device.
Three consecutive measurements will be obtained at the midpoint between the C7 spinous process and the lateral border of the acromion.
The mean of the three measurements will be used.
Stiffness will be expressed in newtons per meter (N/m), with higher values indicating greater stiffness.
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During the single assessment session at enrollment
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Bilateral Upper Trapezius Logarithmic Decrement
Lasso di tempo: During the single assessment session at enrollment
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Upper trapezius logarithmic decrement will be assessed bilaterally using the MyotonPRO device at the same standardized measurement site.
Three consecutive measurements will be obtained on each side, and their mean will be used.
Logarithmic decrement is a dimensionless inverse indicator of tissue elasticity, with lower values indicating greater elasticity.
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During the single assessment session at enrollment
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Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
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Bilateral Handgrip Strength
Lasso di tempo: During the single assessment session at enrollment
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Bilateral handgrip strength will be measured using a Jamar Hydraulic Hand Dynamometer set to the second handle position.
Participants will perform three maximal contractions with each hand in a standardized seated position.
The highest value for each hand will be recorded in kilograms, with higher values indicating greater handgrip strength.
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During the single assessment session at enrollment
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Bilateral Upper Trapezius Pressure Pain Threshold
Lasso di tempo: During the single assessment session at enrollment
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Pressure pain threshold will be measured bilaterally over the upper trapezius using a handheld pressure algometer with a 1-cm² probe.
The measurement site will be the midpoint between the C7 spinous process and the lateral border of the acromion.
Pressure will gradually increase until the participant first reports pain.
Values will be recorded in kg/cm², with higher values indicating a higher pressure pain threshold.
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During the single assessment session at enrollment
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Bilateral Suboccipital Pressure Pain Threshold
Lasso di tempo: During the single assessment session at enrollment
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Pressure pain threshold will be measured bilaterally over the suboccipital region using a handheld pressure algometer with a 1-cm² probe.
The measurement site will be located 2 cm lateral to the C2 spinous process.
Pressure will gradually increase until the participant first reports pain.
Values will be recorded in kg/cm², with higher values indicating a higher pressure pain threshold.
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During the single assessment session at enrollment
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Tragus-to-Wall Distance
Lasso di tempo: During the single assessment session at enrollment
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Tragus-to-wall distance will be measured in millimeters using a tape measure.
Participants will stand with their heels, sacrum, and thoracic spine resting comfortably against a wall while maintaining a natural head position.
The distance between the wall and the tragus will be recorded.
Greater distances indicate greater forward positioning of the head.
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During the single assessment session at enrollment
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Craniovertebral Angle
Lasso di tempo: During the single assessment session at enrollment
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The craniovertebral angle will be measured in degrees using a universal goniometer.
The fulcrum will be positioned over the lateral projection of the C7 spinous process.
The stationary arm will remain parallel to the floor, and the movable arm will point toward the tragus.
Three measurements will be obtained, and their mean will be used.
Smaller angles indicate greater forward head posture.
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During the single assessment session at enrollment
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Collaboratori e investigatori
Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.
Collaboratori
Studiare le date dei record
Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.
Studia le date principali
Inizio studio (Effettivo)
21 aprile 2026
Completamento primario (Stimato)
1 ottobre 2026
Completamento dello studio (Stimato)
1 ottobre 2026
Date di iscrizione allo studio
Primo inviato
17 agosto 2026
Primo inviato che soddisfa i criteri di controllo qualità
17 agosto 2026
Primo Inserito (Effettivo)
20 agosto 2026
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
21 agosto 2026
Ultimo aggiornamento inviato che soddisfa i criteri QC
20 agosto 2026
Ultimo verificato
1 agosto 2026
Maggiori informazioni
Termini relativi a questo studio
Parole chiave
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- E-10840098-50.04-2858
Piano per i dati dei singoli partecipanti (IPD)
Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?
NO
Descrizione del piano IPD
Individual participant data will not be shared.
Study findings will be reported only in aggregate form through scientific publications and presentations.
Informazioni su farmaci e dispositivi, documenti di studio
Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti
No
Studia un dispositivo regolamentato dalla FDA degli Stati Uniti
No
Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .