Metabolic Syndrome and Non-alcoholic Fatty Liver During Pregnancy
Investigation on the Frequency and Obstetric Significance of Metabolic Syndrome and Non-alcoholic Fatty Liver During Pregnancy
調査の概要
詳細な説明
In cases in which metabolic syndrome and non-alcoholic fatty liver are risk factors of obstetric complications, such as gestational diabetes (GDM) or preeclampsia (PE), we are able to offer systematic clinical results from determining the independent risk factor and developing a predictable model. Recently, obstetric complications, especially GDM and PE, have increased due to the growth of elder pregnancy. In addition, as liver dysfunction has been known to be an independent risk factor of diabetes, cardiovascular disease, high blood pressure and renal dysfunction, its clinical importance has risen. Metabolic syndromes, such as obesity, hypertension, type II diabetes and abnormal lipid profile, have been known for its importance in development of non-alcoholic fatty liver disease. Considering abnormal liver function being an independent risk factor of diabetes, cardiovascular disease, high blood pressure and renal dysfunction in normal adult patients, we are able to predict that liver dysfunction might be a high risk factor of obstetric complications in pregnant women. In previous studies, the frequency of liver dysfunction in normal pregnant women was obtained.
The purpose of this current study was to investigate the prevalence of metabolic syndrome, abnormal liver function and non-alcoholic fatty liver in early pregnancy and the related risks of obstetric complications.
研究の種類
入学 (予想される)
連絡先と場所
研究場所
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Incheon、大韓民国、402859
- 募集
- Seoul Women's Hospital
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コンタクト:
- Ja Nam Koo, M.D
- 電話番号:010-8355-2180
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Seoul、大韓民国、110744
- 募集
- Seoul National University Hospital
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コンタクト:
- Joong Shin Park, MD PhD
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コンタクト:
- Sun Min Kim, MD
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Seoul、大韓民国、156707
- 募集
- Seoul Metropolitan Goverment Seoul National University Boramae Medical Center
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コンタクト:
- Seung Mi Lee, M.D, Ph.D.
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参加基準
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Outpatient clinic patients of Seoul National University Hospital, Seoul Metropolitan Government Boramae Medical Center, Incheon Seoul Woman Hospital
- Agree with this study
- Do not drink excess amount of alcohol for recent 2 years
Exclusion Criteria:
- Do not agree with this study
- Do not perform blood tests
- Have underlying hepatobiliary diseases
- Take medications which can cause liver abnormalities
研究計画
研究はどのように設計されていますか?
デザインの詳細
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Compare prevalence of obstetric complications between non-alcoholic fatty liver and normal pregnant women
時間枠:From date of enrollment until the date of delivery, assessed up to 35wks
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Obstetrical complications include gestational diabetes, preeclampsia, etc Non-alcoholic fatty liver diagnosed by using liver ultrasound result of 1st trimester and blood test (AST, APT)
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From date of enrollment until the date of delivery, assessed up to 35wks
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協力者と研究者
捜査官
- 主任研究者:Joong Shin Park, MD PhD、Seoul National University Hospital
出版物と役立つリンク
研究記録日
主要日程の研究
研究開始
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
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