Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Impact of Force Control of Hip Abductor Muscles on Postural Control in Middle-aged and Older Adults and Individuals With Parkinson's Disease
調査の概要
詳細な説明
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations. Previous studies have mainly focused on sagittal plane balance and have identified the important roles of ankle plantar flexors and knee extensors; however, the contribution of hip abductor muscles-key muscles for frontal plane stability-remains unclear, particularly in terms of their force production and control abilities. Therefore, this study aims to investigate hip abductor muscle force production and force control, and to examine whether these factors are associated with postural control, gait, and balance performance in individuals across different ages and those with PD. Healthy young, middle-aged, and older adults will be recruited from the community, and individuals with PD will be recruited from the Department of Neurology. Healthy participants must be in good health, able to walk independently, demonstrate normal cognitive function, and provide informed consent, while those with neurological, cardiovascular, musculoskeletal, or other conditions affecting motor performance will be excluded. For individuals with PD, inclusion criteria will be a clinical diagnosis of idiopathic PD, Hoehn and Yahr stages 1 to 3, stable anti-PD medication use, and the ability to follow instructions and walk at least 10 m. Exclusion criteria will include psychiatric, immune, integumentary, or musculoskeletal disorders, neurological conditions other than PD, lower extremity pain, uncontrolled cardiovascular disease, or inability to provide informed consent. All participants will undergo a one-time assessment, including maximal voluntary isometric contraction, force steadiness, postural control, and gait performance.
Surface electromyography will be used to assess neuromuscular function, postural control will be evaluated using a force plate under multiple standing conditions, and gait parameters will be measured at both comfortable and fast walking speeds. Statistical analyses will be conducted using ANOVA to examine group differences.
研究の種類
入学 (推定)
連絡先と場所
研究連絡先
- 名前：Chu-Ling Yen
- 電話番号：3059 886-3-2118800
- メール：clyen@mail.cgu.edu.tw
研究場所
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-
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Taoyuan、台湾
- 募集
- Chang Gung Memorial Hospital
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コンタクト：
- Chu-Ling Yen
- 電話番号：3059 886-3-2118800
- メール：clyen@mail.cgu.edu.tw
-
Taoyuan、台湾
- 募集
- Chang Gung University
-
コンタクト：
- Chu-Ling Yen
- 電話番号：3059 886-3-2118800
- メール：clyen@mail.cgu.edu.tw
-
-
参加基準
適格基準
就学可能な年齢
- 大人
- 高齢者
健康ボランティアの受け入れ
サンプリング方法
調査対象母集団
説明
Healthy people
Inclusion Criteria:
- 20 to 39 years (young), 40 to 59 years (young), and 60-85 years (old)
- generally in good health
- able to walk 10 m independently
- able to follow all instructions
Exclusion Criteria:
- neurologic, psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
- any pain over the lower extremities
- uncontrolled cardiovascular diseases
- unable to provide informed consent.
PD
Inclusion Criteria:
- clinical diagnosis of idiopathic PD
- Hoehn and Yahr stages 1 to 3
- stable anti-PD medications
- able to walk 10 m independently
- able to follow all instructions
Exclusion Criteria:
- psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
- neurological conditions other than PD
- any pain over the lower extremities
- uncontrolled cardiovascular diseases
- unable to provide informed consent.
研究計画
研究はどのように設計されていますか？
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
|---|---|
|
Healthy people
General healthy adults
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We compare the young, middle-aged, and old groups
We compare the healthy group and PD group.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Maximal force
時間枠：Baseline
|
The maximal force of lower extremity muscles
|
Baseline
|
|
Rate of torque development
時間枠：Baseline
|
The ability to rapidly generate muscle force
|
Baseline
|
|
Force steadiness
時間枠：Baseline
|
The ability to maintain a constant force output during a submaximal contraction
|
Baseline
|
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Walking speed
時間枠：Baseline
|
The time taken by participants to walk a standardized distance
|
Baseline
|
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Step Length
時間枠：Baseline
|
The linear distance between the two ankles, typically expressed in centimeter(cm).
|
Baseline
|
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Cadence
時間枠：Baseline
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The number of steps taken per minute (SPM)
|
Baseline
|
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Single Support Time
時間枠：Baseline
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The duration within the gait cycle when only one foot is in contact with the ground, typically measured in seconds or as a percentage of the total gait cycle.
|
Baseline
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Double Support Time
時間枠：Baseline
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The portion of the gait cycle where both feet are in contact with the ground, indicating the transition phase between steps, expressed as a percentage of the gait cycle or in seconds.
|
Baseline
|
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Swing Time
時間枠：Baseline
|
The portion of the gait cycle where the foot is not in contact with the ground, moving forward to the next step.
It is usually expressed as a percentage of the total gait cycle or in seconds.
|
Baseline
|
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Timed Up-and-Go Test
時間枠：Baseline
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Tthe time an individual takes to stand up from a chair, walk 3 meters, turn around, walk back, and sit down.
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Baseline
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Four Square Step Test
時間枠：Baseline
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Participants will be required to perform four square step test by changing directions while stepping forward, sideway, and backward over a low obstacle as fast as possible.
|
Baseline
|
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Center of Pressure (COP) Velocity in Balance Tasks
時間枠：Baseline
|
The speed at which the COP moves, calculated over the duration of the balance task.
Higher velocities may reflect more dynamic balance adjustments or instability.
Unit：millimeter per second(mm/s)
|
Baseline
|
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Center of Pressure (COP) Area in Balance Tasks
時間枠：Baseline
|
The area covered by the COP trajectory during the balance task, providing an estimate of the sway envelope.
A larger area might indicate poorer balance control.
Unit：square millimeter(mm^2)
|
Baseline
|
協力者と研究者
捜査官
- 主任研究者：Chu-Ling Yen、Chang Gung University
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
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