Multi-Ingredient Supplementation in Professional Football Players (TCP-Soccer)
Dose-Dependent Effects of Multi-Ingredient Supplementation on Physical Performance, Recovery, and Cognitive Function in Professional Football Players
調査の概要
状態
詳細な説明
The planned study will be a randomized, double-blind, placebo-controlled trial designed as a continuation and extension of previous research on multi-ingredient supplementation in professional football players. The primary aim will be to investigate the dose-dependent effects of phosphatidylserine combined with taurine and caffeine under standardized football-specific training conditions and acute cognitive-fatigue conditions.
Approximately 80 professional male football players competing at national level will be randomly assigned to four groups: placebo, taurine + caffeine, taurine + caffeine + phosphatidylserine 300 mg, and taurine + caffeine + phosphatidylserine 600 mg. Importantly, caffeine and taurine doses will remain identical across all active supplementation groups in order to enable a more precise evaluation of the independent effects of phosphatidylserine.
Participants will complete a 14-day supplementation protocol and undergo baseline and post-intervention assessments including 30 m sprint performance, reaction time, cognitive-fatigue responses, football-specific GPS monitoring, fatigue-related performance decline, recovery-related variables, sleep monitoring, and autonomic nervous system activity assessment.
The study is expected to provide novel insights into the role of phosphatidylserine in football-specific performance, cognitive fatigue resistance, recovery, and neurophysiological responses in elite football players.
研究の種類
入学 (実際)
段階
- 適用できない
連絡先と場所
参加基準
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
説明
Inclusion Criteria:
-
Inclusion Criteria:
- Professional male football players aged 18-35 years
- Regular participation in team training and competitive matches
- Clinically healthy status confirmed prior to participation
- Written informed consent provided
Exclusion Criteria:
- Current musculoskeletal injury or illness
- Chronic metabolic, cardiovascular, or neurological disease
- Regular medication use
- Current use of dietary supplements or ergogenic aids
- Smoking or excessive alcohol consumption
- Known hypersensitivity to any study supplement ingredient
Exclusion Criteria:
-
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：他の
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：トリプル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
プラセボコンパレーター：P
Participants will receive visually identical placebo capsules for 14 days.
|
Placebo capsules administered daily during the 14-day intervention period
|
|
実験的：TC
Participants will receive taurine (1500 mg/day) and caffeine (200 mg/day) supplementation for 14 days.
|
Taurine supplementation administered daily during the 14-day intervention period.
Caffeine supplementation administered daily during the 14-day intervention period.
|
|
実験的：TCP-300
Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (300 mg/day) supplementation for 14 days.
|
Taurine supplementation administered daily during the 14-day intervention period.
Caffeine supplementation administered daily during the 14-day intervention period.
Phosphatidylserine supplementation administered daily during the 14-day intervention period.
|
|
実験的：TCP-600
Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (600 mg/day) supplementation for 14 days.
|
Taurine supplementation administered daily during the 14-day intervention period.
Caffeine supplementation administered daily during the 14-day intervention period.
Phosphatidylserine supplementation administered daily during the 14-day intervention period.
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
30 m sprint time
時間枠：Baseline and after 14 days of supplementation
|
Time required to complete a 30 m sprint, measured using electronic timing gates. The best result from three maximal sprint trials will be used for analysis. Unit of Measure: seconds |
Baseline and after 14 days of supplementation
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Visual reaction time
時間枠：Baseline and after 14 days of supplementation
|
Mean response time to a visual stimulus, measured using a validated visual reaction time test.
|
Baseline and after 14 days of supplementation
|
|
Auditory reaction time
時間枠：Baseline and after 14 days of supplementation
|
Mean response time to an auditory stimulus, measured using a computerized auditory reaction time test.
|
Baseline and after 14 days of supplementation
|
|
Total distance covered
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
Total distance covered during the standardized football-specific training session, measured using a 10-Hz GPS tracking system. Unit of Measure: meters |
After 14 days of supplementation, during the standardized football-specific training session
|
|
Relative distance
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
Distance covered per minute during the standardized football-specific training session, measured using a 10-Hz GPS tracking system. Unit of Measure: meters per minute |
After 14 days of supplementation, during the standardized football-specific training session
|
|
High-speed running distance
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
Description: Distance covered at running speeds above 19.8 km/h during the standardized football-specific training session, measured using a 10-Hz GPS tracking system. Unit of Measure: meters |
After 14 days of supplementation, during the standardized football-specific training session
|
|
Number of sprints
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
Total number of sprint efforts performed during the standardized football-specific training session. Sprinting will be defined as running speed above 25.0 km/h and measured using a 10-Hz GPS tracking system. Unit of Measure: number of sprints |
After 14 days of supplementation, during the standardized football-specific training session
|
|
Player Load
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
External training load during the standardized football-specific training session, measured using triaxial accelerometry integrated with the GPS tracking system. Unit of Measure: arbitrary units |
After 14 days of supplementation, during the standardized football-specific training session
|
|
Heart rate variability RMSSD
時間枠：Daily during the 14-day supplementation period
|
Resting heart rate variability assessed in the morning using the root mean square of successive differences between normal heartbeats.
HRV will be measured using a heart rate sensor or wearable device under standardized resting conditions.
Unit of Measure: milliseconds
|
Daily during the 14-day supplementation period
|
|
Sleep duration
時間枠：Daily during the 14-day supplementation period
|
Total sleep duration assessed using wearable sleep monitoring.
Unit of Measure: hours
|
Daily during the 14-day supplementation period
|
|
Sleep efficiency
時間枠：Daily during the 14-day supplementation period
|
Percentage of time in bed spent asleep, assessed using wearable sleep monitoring. Unit of Measure: percent |
Daily during the 14-day supplementation period
|
|
Subjective fatigue
時間枠：Daily during the 14-day supplementation period
|
Subjective fatigue assessed using the fatigue item of the Hooper Index questionnaire on a 1-7 scale, where higher values indicate greater fatigue.
Unit of Measure: score on a scale
|
Daily during the 14-day supplementation period
|
|
Muscle soreness
時間枠：Daily during the 14-day supplementation period
|
Perceived lower-limb muscle soreness assessed using a 0-10 delayed onset muscle soreness scale, where higher values indicate greater soreness. Unit of Measure: score on a scale |
Daily during the 14-day supplementation period
|
|
Stroop task reaction time
時間枠：Baseline and after 14 days of supplementation
|
Mean response time during a modified computerized Stroop task assessing cognitive fatigue, inhibitory control, sustained attention, and information processing speed.
Unit of Measure: seconds
|
Baseline and after 14 days of supplementation
|
|
Stroop task accuracy
時間枠：Baseline and after 14 days of supplementation
|
Percentage of correct responses during a modified computerized Stroop task.
Unit of Measure: percent
|
Baseline and after 14 days of supplementation
|
|
Stroop task error rate
時間枠：Baseline and after 14 days of supplementation
|
Number of incorrect responses during a modified computerized Stroop task.
Unit of Measure: number of errors
|
Baseline and after 14 days of supplementation
|
|
Perceived mental fatigue
時間枠：Baseline and after 14 days of supplementation
|
Subjective perceived mental fatigue assessed using a 0-10 visual analogue scale, where higher values indicate greater perceived mental fatigue.
Unit of Measure: score on a 0-10 scale
|
Baseline and after 14 days of supplementation
|
|
Change in sprint count between first and second half
時間枠：After 14 days of supplementation, during the standardized football-specific training session
|
Percentage decline in the number of sprints between the first and second half of the standardized football-specific training session. Sprint change will be calculated as: [(second half value - first half value) / first half value] × 100. Unit of Measure: percent |
After 14 days of supplementation, during the standardized football-specific training session
|
協力者と研究者
捜査官
- 主任研究者：Krzysztof Maciej MIZERA, PhD、1. Vizja University in Warsaw, Faculty of Medical Sciences and Health Sciences, 01-143 Warsaw, Poland
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- MIZERA-FOOTBALL-2026
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
IPD プランの説明
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。