MEG and Aphantasia (MEGAPHANTASIA)
Cerebral Oscillations During Covert Actions in Aphantasia
Covert actions are cognitive processes that involves the motor system. They include motor imagery, movement preparation, action observation or action language. They imply mental simulations, based on activations of neural networks, involved in specific operations such as perceiving or acting. These mental phenomena have intrigued and still intrigue philosophers, psychologists, and neuroscientists, as they are complex and introspective processes, which play a major role in human cognition.
To decipher similarities and differences between these types of covert actions, the investigators will focus on persons living with aphantasia, which is a neurocognitive specificity present in a small proportion of the population (5 to 8%). Aphantasia is characterized by the alteration or the absence of explicit mental representations.
This population offers an ideal testbed to disentangle the involvement of cognitive and motor processes in different forms of covert actions.
By means of magnetoencephalography, this study aims to identify and compare brain patterns and their temporal dynamics in alpha and beta bands during covert actions in two groups of healthy volunteers: aphantasics and non-aphantasics (i.e., having a non-altered imagery capacity).
If covert actions indeed share brain networks, the investigators expect aphantasics to present reduced neural and behavioral activation during the explicit (i.e., motor imagery) and implicit (movement preparation, action language and action observation) forms of covert actions.
調査の概要
状態
条件
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前：Florent LEBON, PhD
- 電話番号：+336 450 445 26
- メール：florent.lebon@univ-lyon1.fr
研究場所
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Bron、フランス
- CERMEP
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コンタクト：
- Yves ROSSETTI, Professor
- 電話番号：+334.78.86.50.21
- メール：yves.rossetti@inserm.fr
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主任研究者：
- Yves ROSSETTI, Professor
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-
参加基準
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
説明
Inclusion Criteria:
- Aged 18 to 60 years
- Willing to actively participate in the study
- Having signed an informed consent form to participate in the study
Inclusion Failure Criteria:
Identification of individuals with and without aphantasia based on responses to a questionnaire validated in the literature: Vividness of Movement Imagery Questionnaire, second version (VMIQ-2):
Scores required for inclusion in the aphantasic group
- VMIQ-2: internal visual imagery score = 55-60
- VMIQ-2: kinesthetic imagery score = 55-60
Scores required for inclusion in the non-aphantasic group
- VMIQ-2: internal visual imagery score = 20-36
- VMIQ-2: kinesthetic imagery score = 20-36
Exclusion Criteria:
- Neurological or psychiatric disorders
- History of neurological or psychiatric disorders
- Sleep disorders that may affect data variability or quality, or participant cooperation and retention, as assessed by the principal investigator or co-investigator during the inclusion interview
- Volunteers presenting standard contraindications to MEG and MRI examinations:
- Presence of incompatible metal in the body (pacemaker, implanted pump including insulin pump, neurostimulator, cochlear implants or other hearing devices, metallic prosthesis, intracerebral/surgical aneurysm clips, implantable defibrillator, ferromagnetic foreign bodies in the eyes or brain in the upper body, ventriculoperitoneal shunt valves, dental braces or steel posts in root canals, ferromagnetic foreign bodies in the upper body)
- Claustrophobia
- Pregnant or breastfeeding women
- Individuals under guardianship, curatorship, or legal protection
- Individuals deprived of liberty
- Individuals undergoing psychiatric care
- Individuals admitted to a health or social institution for reasons other than clinical research
- Individuals not affiliated with a social security system or not beneficiaries of such a system
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：非ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的：Aphantasics
Healthy individuals with altered mental imagery (score between 55 and 60 for each modality at the vividness of motor imagery questionnaire - second version)
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Before MEG and MRI, measure of vividness for internal visual imagery, external visual imagery and kinesthetic imagery (for 12 actions).
Within a single session, measure of brain oscillations during four types of covert actions (motor imagery, action observation, action language and movement preparation).
Anatomical MRI, performed once
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アクティブコンパレータ：Non-aphantasics
Healthy individuals with non-altered mental imagery (score between 20 and 36 for each modality at the vividness of motor imagery questionnaire - second version)
|
Before MEG and MRI, measure of vividness for internal visual imagery, external visual imagery and kinesthetic imagery (for 12 actions).
Within a single session, measure of brain oscillations during four types of covert actions (motor imagery, action observation, action language and movement preparation).
Anatomical MRI, performed once
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Whole-brain power of beta band (Tesla2)
時間枠：During MEG recording
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Power of beta band with whole brain analysis during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Whole-brain power of alpha band (Tesla2)
時間枠：During MEG recording
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Power of alpha band with whole brain analysis during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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Power of beta band (Tesla2) in the primary motor cortex
時間枠：During MEG recording
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Power of beta band in M1 during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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Power of alpha band (Tesla2) in the primary motor cortex
時間枠：During MEG recording
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Power of alpha band in M1 during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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協力者と研究者
スポンサー
捜査官
- 主任研究者：Yves ROSSETTI, Professor、Hospices Civils de Lyon
- スタディディレクター：Florent LEBON, PhD、Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM UR7424)
研究記録日
主要日程の研究
研究開始 (推定)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
キーワード
その他の研究ID番号
- 69HCL26_0176
- 2026-A01303-48 (その他の識別子：ID-RCB)
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