MEG and Aphantasia (MEGAPHANTASIA)
Cerebral Oscillations During Covert Actions in Aphantasia
Covert actions are cognitive processes that involves the motor system. They include motor imagery, movement preparation, action observation or action language. They imply mental simulations, based on activations of neural networks, involved in specific operations such as perceiving or acting. These mental phenomena have intrigued and still intrigue philosophers, psychologists, and neuroscientists, as they are complex and introspective processes, which play a major role in human cognition.
To decipher similarities and differences between these types of covert actions, the investigators will focus on persons living with aphantasia, which is a neurocognitive specificity present in a small proportion of the population (5 to 8%). Aphantasia is characterized by the alteration or the absence of explicit mental representations.
This population offers an ideal testbed to disentangle the involvement of cognitive and motor processes in different forms of covert actions.
By means of magnetoencephalography, this study aims to identify and compare brain patterns and their temporal dynamics in alpha and beta bands during covert actions in two groups of healthy volunteers: aphantasics and non-aphantasics (i.e., having a non-altered imagery capacity).
If covert actions indeed share brain networks, the investigators expect aphantasics to present reduced neural and behavioral activation during the explicit (i.e., motor imagery) and implicit (movement preparation, action language and action observation) forms of covert actions.
연구 개요
상태
정황
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 연락처
- 이름: Florent LEBON, PhD
- 전화번호: +336 450 445 26
- 이메일: florent.lebon@univ-lyon1.fr
연구 장소
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Bron, 프랑스
- CERMEP
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연락하다:
- Yves ROSSETTI, Professor
- 전화번호: +334.78.86.50.21
- 이메일: yves.rossetti@inserm.fr
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수석 연구원:
- Yves ROSSETTI, Professor
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참여기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Aged 18 to 60 years
- Willing to actively participate in the study
- Having signed an informed consent form to participate in the study
Inclusion Failure Criteria:
Identification of individuals with and without aphantasia based on responses to a questionnaire validated in the literature: Vividness of Movement Imagery Questionnaire, second version (VMIQ-2):
Scores required for inclusion in the aphantasic group
- VMIQ-2: internal visual imagery score = 55-60
- VMIQ-2: kinesthetic imagery score = 55-60
Scores required for inclusion in the non-aphantasic group
- VMIQ-2: internal visual imagery score = 20-36
- VMIQ-2: kinesthetic imagery score = 20-36
Exclusion Criteria:
- Neurological or psychiatric disorders
- History of neurological or psychiatric disorders
- Sleep disorders that may affect data variability or quality, or participant cooperation and retention, as assessed by the principal investigator or co-investigator during the inclusion interview
- Volunteers presenting standard contraindications to MEG and MRI examinations:
- Presence of incompatible metal in the body (pacemaker, implanted pump including insulin pump, neurostimulator, cochlear implants or other hearing devices, metallic prosthesis, intracerebral/surgical aneurysm clips, implantable defibrillator, ferromagnetic foreign bodies in the eyes or brain in the upper body, ventriculoperitoneal shunt valves, dental braces or steel posts in root canals, ferromagnetic foreign bodies in the upper body)
- Claustrophobia
- Pregnant or breastfeeding women
- Individuals under guardianship, curatorship, or legal protection
- Individuals deprived of liberty
- Individuals undergoing psychiatric care
- Individuals admitted to a health or social institution for reasons other than clinical research
- Individuals not affiliated with a social security system or not beneficiaries of such a system
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위화되지 않음
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: Aphantasics
Healthy individuals with altered mental imagery (score between 55 and 60 for each modality at the vividness of motor imagery questionnaire - second version)
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Before MEG and MRI, measure of vividness for internal visual imagery, external visual imagery and kinesthetic imagery (for 12 actions).
Within a single session, measure of brain oscillations during four types of covert actions (motor imagery, action observation, action language and movement preparation).
Anatomical MRI, performed once
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활성 비교기: Non-aphantasics
Healthy individuals with non-altered mental imagery (score between 20 and 36 for each modality at the vividness of motor imagery questionnaire - second version)
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Before MEG and MRI, measure of vividness for internal visual imagery, external visual imagery and kinesthetic imagery (for 12 actions).
Within a single session, measure of brain oscillations during four types of covert actions (motor imagery, action observation, action language and movement preparation).
Anatomical MRI, performed once
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Whole-brain power of beta band (Tesla2)
기간: During MEG recording
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Power of beta band with whole brain analysis during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Whole-brain power of alpha band (Tesla2)
기간: During MEG recording
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Power of alpha band with whole brain analysis during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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Power of beta band (Tesla2) in the primary motor cortex
기간: During MEG recording
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Power of beta band in M1 during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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Power of alpha band (Tesla2) in the primary motor cortex
기간: During MEG recording
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Power of alpha band in M1 during each of the four covert actions (motor imagery, action observation, movement preparation and action language).
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During MEG recording
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공동 작업자 및 조사자
수사관
- 수석 연구원: Yves ROSSETTI, Professor, Hospices Civils de Lyon
- 연구 책임자: Florent LEBON, PhD, Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM UR7424)
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- 69HCL26_0176
- 2026-A01303-48 (기타 식별자: ID-RCB)
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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