Blood Flow Restriction and Aerobic Exercise in Iron Deficiency Anemia (BFR-IDA)
2026年7月8日 更新者：noha sameh、Cairo University
Impact of Blood Flow Restriction on Hematological Factors in Anemic Young Females
Preventing iron deficiency anemia is essential for strengthening adolescent health and ensuring their full development.
Strategies such as improving nutrition, expanding the availability of iron-fortified products, implementing pharmacological prevention, and raising awareness play a crucial role in addressing this issue.
調査の概要
詳細な説明
Anemia is a global public health problem affecting both developing and developed countries at all ages, with major consequences for human health as well as social and economic burden. Iron deficiency affects more than 2 billion people world wide, and iron deficiency anemia (IDA) remains to be the top cause of anemia.
For decades, blood flow restriction (BFR), originating from Japan, has become one of the most popular techniques in physiotherapy. To perform the BFR technique, a controlled tourniquet is performed, generating a gradual mechanical pressure just below it, affecting blood flow (both arterial and venous) and generating a hypoxia in the restricted area. For the realization of the tourniquet, mechanical cuffs are used, which are inflated and regulate the pressure generated in the compression zone, although nylon or elastic cuffs are also used for the realization of the tourniquet.
研究の種類
介入
入学 (推定)
50
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究連絡先
- 名前：noha sameh donia, assisstant lecturer
- 電話番号：01275600448
- メール：nohasameh92.ns@gmail.com
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
いいえ
説明
Inclusion Criteria:
- Hb more than 8 and less than 12 in females.
- Age: 19-25 year.
- BMI ranging from 25 to 29.9 kg/m2.
- No existing inflammatory conditions including rheumatoid arthritis disorders of the lower extremities.
- Physical activity level less than 150 min per week
Exclusion Criteria:
- unstable hypertension, venous thromboembolism, hypercoagulable states, varicose veins, pregnancy, and hemophilia.
- inherited or acquired red cell disorders (haemoglobinopathies).
- acute or chronic infections (malaria, tuberculosis, HIV),.
- severe anemia (Hb <8 g/dL).
- History of cardiovascular diseases.
- Nutritional anemia (B12/folate)
- Pregnancy.
- Peripheral arterial disease.
- Intermittent claudication.
- Non smokers
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
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実験的：Aerobic Exercise + Blood Flow Restriction
25 female will receive blood flow restriction with low intensity aerobic exercise participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h.
They experienced 3 session/week and each session include 5-10 minutes warming up and five training sets (each lasting 2 min) with a 1 min rest period between each exercise session and ended with 5-10 minutes cooling down A pressure of between 140 and 200 mmHg was applied using a sphygmomanometer cuff placed at the thigh of the BFR group.
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Twenty five females will be subjected to supervised blood flow restriction combined with aerobic exercise program.
participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h.
They experienced 3 session/week and each session include 5-10 minutes .A pressure of between 140 and 200 mmHg was applied using a sphygmomanometer cuff placed at the thigh of the BFR group.
The pressure of the cuff was increased until the participants adapted to the restriction stimulus during the early phase of training, and this pressure was maintained used during the training protocol.
The strap pressure was increased by 10 mmHg per week, such that it reached 200 mmHg by the end of 12th week.
The pressure on the thigh strap was abruptly released after five completions of the exercise set.
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アクティブコンパレータ：Aerobic Exercise
25 subject participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h.
They experienced 3 session/week and each session include 5-10 minutes warming up and five training sets (each lasting 2 min) with a 1 min rest period between each exercise session and ended with 5-10 minutes cooling down.
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participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h.
They experienced 3 session/week and each session include 5-10 minutes warming up and five training sets (each lasting 2 min) with a 1 min rest period between each exercise session and ended with 5-10 minutes cooling down.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
時間枠 |
|---|---|
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haemoglobin concentration
時間枠：Baseline and 12 weeks
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Baseline and 12 weeks
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Serum ferritin level
時間枠：Baseline and at 12 weeks
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Baseline and at 12 weeks
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Haematocrit
時間枠：Baseline and at 12 weeks
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Baseline and at 12 weeks
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Red blood cell (RBC) count
時間枠：baseline and at 12 week
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baseline and at 12 week
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Mean corpuscular volume (MCV)
時間枠：baseline and at 12 week
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baseline and at 12 week
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Mean corpuscular haemoglobin (MCH)
時間枠：baseline and at 12 week
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baseline and at 12 week
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二次結果の測定
結果測定 |
時間枠 |
|---|---|
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Functional capacity assessed using the Incremental Shuttle Walk Test (ISWT)
時間枠：baseline and at 12 week
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baseline and at 12 week
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Quality of life assessed using the SF-36 questionnaire
時間枠：baseline and at 12 week
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baseline and at 12 week
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Estimated maximal oxygen consumption (VO₂max) derived from the ISWT
時間枠：baseline and at 12 week
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baseline and at 12 week
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
スポンサー
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (推定)
2026年7月25日
一次修了 (推定)
2026年10月30日
研究の完了 (推定)
2026年11月5日
試験登録日
最初に提出
2026年7月2日
QC基準を満たした最初の提出物
2026年7月8日
最初の投稿 (実際)
2026年7月14日
学習記録の更新
投稿された最後の更新 (実際)
2026年7月14日
QC基準を満たした最後の更新が送信されました
2026年7月8日
最終確認日
2026年7月1日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- P.T.REC/012/006440 (その他の識別子：faculty of physical therapy cairo University ethical Committee)
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
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